Search Results - "Kurakula, Mallesh"

In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma by Kurakula, Mallesh, Naveen, N Raghavendra

“…The goal of this study is to develop optimized chitosan-coated Simvastatin (SIM) nanoparticles (NPs) loaded in an in situ gel (ISG) formulation via a…”
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Effect of Cationic Lipid Nanoparticle Loaded siRNA with Stearylamine against Chikungunya Virus by Jeengar, Manish Kumar, Kurakula, Mallesh, Patil, Poonam, More, Ashwini, Sistla, Ramakrishna, Parashar, Deepti

“…Chikungunya is an infectious disease caused by mosquito-transmitted chikungunya virus (CHIKV). It was reported that NS1 and E2 siRNAs administration…”
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Preparation, Optimization and Evaluation of Chitosan-Based Avanafil Nanocomplex Utilizing Antioxidants for Enhanced Neuroprotective Effect on PC12 Cells by Kurakula, Mallesh, Naveen N., Raghavendra, Patel, Bhaumik, Manne, Ravi, Patel, Devang B.

“…(1) Introduction: in recent decades, interdisciplinary research on the utilization of natural products as “active moiety carriers” was focused on due to their…”
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Co-Delivery of Atorvastatin Nanocrystals in PLGA based in situ Gel for Anti-Hyperlipidemic Efficacy by Kurakula, Mallesh, Ahmed, Tarek A

“…The objective was to develop chitosan atorvastatin (ATR) nanocrystals loaded into Poly (lactic-co-glycolic) acid (PLGA) injectable in situ gel (ISG) system…”
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Chitosan as Functional Biomaterial for Designing Delivery Systems in Cardiac Therapies by Patel, Bhaumik, Manne, Ravi, Patel, Devang B, Gorityala, Shashank, Palaniappan, Arunkumar, Kurakula, Mallesh

“…Cardiovascular diseases are a leading cause of mortality across the globe, and transplant surgeries are not always successful since it is not always possible…”
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Development, optimization, and evaluation of a nanostructured lipid carrier of sesame oil loaded with miconazole for the treatment of oral candidiasis by Hosny, Khaled M., Sindi, Amal M., Ali, Sarah, Alharbi, Waleed S., Hajjaj, Maher S., Bukhary, Haitham A., Badr, Moutaz Y., Mushtaq, Rayan Y., Murshid, Samar S. A., Almehmady, Alshaimaa M., Bakhaidar, Rana B., Alfayez, Eman, Kurakula, Mallesh

“…Candida albicans is the fungus responsible for oral candidiasis, a prevalent disease. The development of antifungal-based delivery systems has always been a…”
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Pharmacological Exploration of Phenolic Compound: Raspberry Ketone—Update 2020 by Rao, Shailaja, Kurakula, Mallesh, Mamidipalli, Nagarjuna, Tiyyagura, Papireddy, Patel, Bhaumik, Manne, Ravi

“…Raspberry ketone (RK) is an aromatic phenolic compound naturally occurring in red raspberries, kiwifruit, peaches, and apples and reported for its potential…”
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Synthesis and Characterization of 2-Decenoic Acid Modified Chitosan for Infection Prevention and Tissue Engineering by Wells, Carlos Montez, Coleman, Emily Carol, Yeasmin, Rabeta, Harrison, Zoe Lynn, Kurakula, Mallesh, Baker, Daniel L, Bumgardner, Joel David, Fujiwara, Tomoko, Jennings, Jessica Amber

“…Chitosan nanofiber membranes are recognized as functional antimicrobial materials, as they can effectively provide a barrier that guides tissue growth and…”
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Recent Trends in Assessment of Cellulose Derivatives in Designing Novel and Nanoparticulate-Based Drug Delivery Systems for Improvement of Oral Health by Hosny, Khaled M, Alkhalidi, Hala M, Alharbi, Waleed S, Md, Shadab, Sindi, Amal M, Ali, Sarah A, Bakhaidar, Rana B, Almehmady, Alshaimaa M, Alfayez, Eman, Kurakula, Mallesh

“…Natural polymers are revolutionizing current pharmaceutical dosage forms design as excipient and gained huge importance because of significant influence in…”
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Strontium and selenium doped bioceramics incorporated polyacrylamide-carboxymethylcellulose hydrogel scaffolds: mimicking key features of bone regeneration by Sarin, Nonita, Kurakula, Mallesh, Singh, K.J., Kumar, Anuj, Singh, Davinder, Arora, Saroj

“…Polyacrylamide-carboxymethylcellulose hydrogels lack mechanical strength, uncontrolled rate of degradation, and poor osteogenic properties which can be…”
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Enhancement of antifungal activity and transdermal delivery of 5-flucytosine via tailored spanlastic nanovesicles: statistical optimization, in-vitro characterization, and in-vivo biodistribution study by Safhi, Awaji Y, Naveen, Nimbagal Raghavendra, Rolla, Krishna Jayanth, Bhavani, Penmetsa Durga, Kurakula, Mallesh, Hosny, Khaled M, Abualsunun, Walaa A, Alissa, Mohammed, Alsalhi, Abdullah, Alahmadi, Amerh Aiad, Zoghebi, Khalid, Halwaani, Abdulrahman Sindam, Ibrahim K, Rasha

“…This current study aimed to load 5-flucytosine (5-FCY) into spanlastic nanovesicles (SPLNs) to make the drug more efficient as an antifungal and also to load…”
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Development of omega-3 loxoprofen-loaded nanoemulsion to limit the side effect associated with NSAIDs in treatment of tooth pain by Hosny, Khaled M., Sindi, Amal M., Alkhalidi, Hala M., Kurakula, Mallesh, Hassan, Amira H., Bakhaidar, Rana B., Abualsunun, Walaa A., Almehmady, Alshaimaa M., Khames, Ahmed, Rizg, Waleed Y., Khallaf, Rasha A., Alruwaili, Nabil K., Alhakamy, Nabil A.

“…The majority of newly developed drugs need to be incorporated with delivery systems to maximize their effect and minimize side effects. Nanoemulsions (NEs) are…”
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Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity by Alhakamy, Nabil A, Fahmy, Usama A, Ahmed, Osama A A, Caruso, Giuseppe, Caraci, Filippo, Asfour, Hani Z, Bakhrebah, Muhammed A, N Alomary, Mohammad, Abdulaal, Wesam H, Okbazghi, Solomon Z, Abdel-Naim, Ashraf B, Eid, Basma G, Aldawsari, Hibah M, Kurakula, Mallesh, Mohamed, Amir I

“…This work aimed at improving the targeting and cytotoxicity of simvastatin (SMV) against colon cancer cells. SMV was encapsulated in chitosan polymers,…”
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Response Surface Methodology (RSM) Powered Formulation Development, Optimization and Evaluation of Thiolated Based Mucoadhesive Nanocrystals for Local Delivery of Simvastatin by Bakhaidar, Rana B, Naveen, Nimbagal Raghavendra, Basim, Pratap, Murshid, Samar S, Kurakula, Mallesh, Alamoudi, Abdulmohsin J, Bukhary, Deena M, Jali, Abdulmajeed M, Majrashi, Mohammed A, Alshehri, Sameer, Alissa, Mohammed, Ahmed, Rayan A

“…In oral administration systems, mucoadhesive polymers are crucial for drug localization and target-specific activities. The current work focuses on the…”
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Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation by Hosny, Khaled M., Alhakamy, Nabil A., Almodhwahi, Maeen A., Kurakula, Mallesh, Almehmady, Alshaimaa M., Elgebaly, Samar S.

“…Sildenafil citrate is a drug used throughout the world primarily to treat erectile dysfunction. Several problems with the commercially available product…”
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Development of Novel S-Protective Thiolated-Based Mucoadhesive Tablets for Repaglinide: Pharmacokinetic Study by Alhakamy, Nabil A, Naveen, Nimbagal Raghavendra, Gorityala, Shashank, Kurakula, Mallesh, Hosny, Khaled M, Safhi, Awaji Y, Bukhary, Deena M, Bukhary, Haitham A, Sabei, Fahad Y, Mushtaq, Rayan Y, Murshid, Samar S

“…Mucoadhesive polymers have an essential role in drug localization and target-specific actions in oral delivery systems. The current work aims to develop and…”
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Design and evaluation of magnetic-targeted bilosomal gel for rheumatoid arthritis: flurbiprofen delivery using superparamagnetic iron oxide nanoparticles by Mushtaq, Rayan Y, Naveen, Nimbagal Raghavendra, Rolla, Krishna Jayanth, Al Shmrany, Humood, Alshehri, Sameer, Salawi, Ahmad, Kurakula, Mallesh, Alghamdi, Majed A, Rizg, Waleed Y, Bakhaidar, Rana B, Abualsunun, Walaa A, Hosny, Khaled M, Alamoudi, Abdulmohsin J

“…The study aimed to systematically enhance the fabrication process of flurbiprofen-loaded bilosomes (FSB) using Quality by Design (QbD) principles and Design of…”
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Chitosan based atorvastatin nanocrystals: effect of cationic charge on particle size, formulation stability, and in-vivo efficacy by Kurakula, Mallesh, El-Helw, A M, Sobahi, Tariq R, Abdelaal, Magdy Y

“…Cationic charged chitosan as stabilizer was evaluated in preparation of nanocrystals using probe sonication method. The influence of cationic charge densities…”
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Design and Development of Neomycin Sulfate Gel Loaded with Solid Lipid Nanoparticles for Buccal Mucosal Wound Healing by Hosny, Khaled M., Naveen, N. Raghavendra, Kurakula, Mallesh, Sindi, Amal M., Sabei, Fahad Y., Fatease, Adel Al, Jali, Abdulmajeed M., Alharbi, Waleed S., Mushtaq, Rayan Y., Felemban, Majed, Tayeb, Hossam H., Alfayez, Eman, Rizg, Waleed Y.

“…Drug administration to the wound site is a potential method for wound healing. The drug retention duration should be extended, and drug permeability through…”
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Oral gel loaded with penciclovir-lavender oil nanoemulsion to enhance bioavailability and alleviate pain associated with herpes labialis by Hosny, Khaled M., Sindi, Amal M., Alkhalidi, Hala M., Kurakula, Mallesh, Alruwaili, Nabil K., Alhakamy, Nabil A., Abualsunun, Walaa A., Bakhaidar, Rana B., Bahmdan, Rahaf H., Rizg, Waleed Y., Ali, Sarah A., Abdulaal, Wesam H., Nassar, Majed S., Alsuabeyl, Mohammed S., Alghaith, Adel F., Alshehri, Sultan

“…Herpes labialis, caused by herpes simplex virus type 1, is usually characterized by painful skin or mucosal lesions. Penciclovir (PV) tablets are found to be…”
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