Search Results - "Kurahashi, Ryoma"

MicroRNA‐204‐5p: A novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma by Kurahashi, Ryoma, Kadomatsu, Tsuyoshi, Baba, Masaya, Hara, Chiaki, Itoh, Hitoshi, Miyata, Keishi, Endo, Motoyoshi, Morinaga, Jun, Terada, Kazutoyo, Araki, Kimi, Eto, Masatoshi, Schmidt, Laura S., Kamba, Tomomi, Linehan, W. Marston, Oike, Yuichi

“…Xp11.2 translocation renal cell carcinoma (Xp11 tRCC) is a rare sporadic pediatric kidney cancer caused by constitutively active TFE3 fusion proteins. Tumors…”
Get full text

TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma by Itoh, Hitoshi, Kadomatsu, Tsuyoshi, Tanoue, Hironori, Yugami, Masaki, Miyata, Keishi, Endo, Motoyoshi, Morinaga, Jun, Kobayashi, Eisuke, Miyamoto, Takeshi, Kurahashi, Ryoma, Terada, Kazutoyo, Mizuta, Hiroshi, Oike, Yuichi

“…The tumor microenvironment promotes epigenetic changes in tumor cells associated with tumor aggressiveness. Here we report that in primary tumor cells,…”
Get full text

Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity by Horiguchi, Haruki, Kadomatsu, Tsuyoshi, Kurahashi, Ryoma, Hara, Chiaki, Miyata, Keishi, Baba, Masaya, Osumi, Hironobu, Terada, Kazutoyo, Araki, Kimi, Takai, Toshiyuki, Kamba, Tomomi, Linehan, W Marston, Moroishi, Toshiro, Oike, Yuichi

“…Angiopoietin-like protein 2 (ANGPTL2) is a secreted glycoprotein homologous to angiopoietins. Previous studies suggest that tumor cell-derived ANGPTL2 has…”
Get full text

TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease by Baba, Masaya, Furuya, Mitsuko, Motoshima, Takanobu, Lang, Martin, Funasaki, Shintaro, Ma, Wenjuan, Sun, Hong-Wei, Hasumi, Hisashi, Huang, Ying, Kato, Ikuma, Kadomatsu, Tsuyoshi, Satou, Yorifumi, Morris, Nicole, Karim, Baktiar O, Ileva, Lilia, Kalen, Joseph D, Wilan Krisna, Luh Ade, Hasumi, Yukiko, Sugiyama, Aiko, Kurahashi, Ryoma, Nishimoto, Koshiro, Oyama, Masafumi, Nagashima, Yoji, Kuroda, Naoto, Araki, Kimi, Eto, Masatoshi, Yao, Masahiro, Kamba, Tomomi, Suda, Toshio, Oike, Yuichi, Schmidt, Laura S, Linehan, W Marston

“…Renal cell carcinoma (RCC) associated with Xp11.2 translocation (TFE3-RCC) has been recently defined as a distinct subset of RCC classified by characteristic…”
Get full text

Clinical Impact of Detecting Low-Frequency Variants in Cell-Free DNA on Treatment of Castration-Resistant Prostate Cancer by Mizuno, Kei, Sumiyoshi, Takayuki, Okegawa, Takatsugu, Terada, Naoki, Ishitoya, Satoshi, Miyazaki, Yu, Kojima, Takahiro, Katayama, Hiromichi, Fujimoto, Naohiro, Hatakeyama, Shingo, Shiota, Masaki, Yoshimura, Koji, Matsui, Yoshiyuki, Narita, Shintaro, Matsumoto, Hiroaki, Kurahashi, Ryoma, Kanno, Hidenori, Ito, Katsuhiro, Kimura, Hiroko, Kamiyama, Yuki, Sunada, Takuro, Goto, Takayuki, Kobayashi, Takashi, Yamada, Hitoshi, Tsuchiya, Norihiko, Kamba, Tomomi, Matsuyama, Hideyasu, Habuchi, Tomonori, Eto, Masatoshi, Ohyama, Chikara, Ito, Akihiro, Nishiyama, Hiroyuki, Okuno, Hiroshi, Kamoto, Toshiyuki, Fujimoto, Akihiro, Ogawa, Osamu, Akamatsu, Shusuke

“…Although cell-free DNA (cfDNA) testing is expected to drive cancer precision medicine, little is known about the significance of detecting low-frequency…”
Get full text

Immune‐related adverse events in urothelial cancer patients: Adjustment for immortal time bias by Otsuka, Hikari, Kita, Yuki, Ito, Katsuhiro, Sano, Takeshi, Inokuchi, Junichi, Tomida, Ryotaro, Takahashi, Atsushi, Matsumoto, Kazumasa, Kurahashi, Ryoma, Ozaki, Yu, Uegaki, Masayuki, Maruyama, Satoru, Mukai, Shoichiro, Tsutsumi, Masakazu, Kawahara, Takashi, Segawa, Takehiko, Kitamura, Hiroshi, Morita, Satoshi, Kobayashi, Takashi

“…To investigate the association between the onset, severity, and type of immune‐related adverse events (irAEs) and the efficacy of pembrolizumab in patients…”
Get full text

ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion by Kadomatsu, Tsuyoshi, Hara, Chiaki, Kurahashi, Ryoma, Horiguchi, Haruki, Morinaga, Jun, Miyata, Keishi, Kurano, Sohtaro, Kanemaru, Hisashi, Fukushima, Satoshi, Araki, Kimi, Baba, Masaya, Linehan, W. Marston, Kamba, Tomomi, Oike, Yuichi

“…Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that…”
Get full text

High T-cell infiltration in tumor tissue and younger age predict the response to pembrolizumab in recurrent urothelial cancer by Anami, Toshiki, Komohara, Yoshihiro, Miura, Yuji, Yamanaka, Kotaro, Kurahashi, Ryoma, Segawa, Takuya, Motoshima, Takanobu, Murakami, Yoji, Yatsuda, Junji, Yamaguchi, Takahiro, Sugiyama, Yutaka, Jinnouchi, Yoshiteru, Kamba, Tomomi

“…Targeting the programmed cell death-1 signaling pathway has been approved for the anti-cancer therapy in several cancers including urothelial cancer. To…”
Get full text

Effects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy by Kubota, Masashi, Kawakita, Mutsushi, Yoshida, Satomi, Kimura, Hiroko, Sumiyoshi, Takayuki, Yamasaki, Toshinari, Okumura, Kazuhiro, Yoshimura, Koji, Matsui, Yoshiyuki, Sugiyama, Kyohei, Okuno, Hiroshi, Segawa, Takehiko, Shimizu, Yosuke, Ito, Noriyuki, Onishi, Hiroyuki, Ishitoya, Satoshi, Soda, Takeshi, Yoshida, Toru, Uemura, Yuichi, Iwamura, Hiroshi, Okubo, Kazutoshi, Suzuki, Ryosuke, Fukuzawa, Shigeki, Akao, Toshiya, Kurahashi, Ryoma, Shimatani, Kimihiro, Sekine, Yuya, Negoro, Hiromitsu, Akamatsu, Shusuke, Kamoto, Toshiyuki, Ogawa, Osamu, Kawakami, Koji, Kobayashi, Takashi, Goto, Takayuki

“…This study aimed to assess the effects of thienopyridine-class antiplatelet agents (including ticlopidine, clopidogrel, and prasugrel) on bleeding…”
Get full text

Sicca syndrome during ipilimumab and nivolumab therapy for metastatic renal cell carcinoma by Segawa, Takuya, Motoshima, Takanobu, Yatsuda, Junji, Kurahashi, Ryoma, Fukushima, Yumi, Murakami, Yoji, Yamaguchi, Takahiro, Sugiyama, Yutaka, Yoshida, Ryoji, Nakayama, Hideki, Kamba, Tomomi

“…Introduction Dry mouth is the main symptom of sicca syndrome, which rarely occurs as an immune‐related adverse event. Here we report a case of sicca syndrome…”
Get full text

Impact of the objective response to and number of cycles of platinum‐based first‐line chemotherapy for metastatic urothelial carcinoma on overall survival of patients treated with pembrolizumab by Kato, Minoru, Kobayashi, Takashi, Matsui, Yoshiyuki, Ito, Katsuhiro, Hikami, Kensuke, Yamada, Takeshi, Ogawa, Kosuke, Nakamura, Kenji, Sassa, Naoto, Yokomizo, Akira, Abe, Takashige, Tsuchihashi, Kazunari, Tatarano, Shuichi, Inokuchi, Junichi, Tomida, Ryotaro, Fujiwara, Maki, Takahashi, Atsushi, Matsumoto, Kazumasa, Shimizu, Kosuke, Araki, Hiromasa, Kurahashi, Ryoma, Ozaki, Yu, Tashiro, Yu, Uegaki, Masayuki, Kojima, Takahiro, Uchida, Junji, Ogawa, Osamu, Nishiyama, Hiroyuki, Kitamura, Hiroshi, Hatakeyama, Shingo, Matsushita, Yuto, Naito, Sei, Shiga, Masanobu, Miyake, Makito, Muro, Yusuke, Nakanishi, Shotaro, Kato, Yoichiro, Shibuya, Tadamasa, Hayashi, Tetsutaro, Yasumoto, Hiroaki, Yoshida, Takashi, Uemura, Motohide, Taoka, Rikiya, Kamiyama, Manabu, Maruyama, Satoru, Mukai, Shoichiro, Tsutsumi, Masakazu, Miki, Jun, Okuno, Tomoya, Yoshio, Yuko, Matsumoto, Hiroaki, Shimazui, Toru, Segawa, Takehiko, Karashima, Takashi, Masui, Kimihiko, Fukuta, Fumimasa, Tashiro, Kojiro, Imai, Kazuto, Suekane, Shigetaka, Nagasawa, Seiji, Higashi, Shin, Fukui, Tomohiro

“…Objectives To investigate the impact of the number of cycles and objective response to chemotherapy on overall survival in patients with metastatic urothelial…”
Get full text

Subcapsular renal hematoma after ureterorenoscopy by Harada, Narumi, Yatsuda, Junji, Kurahashi, Ryoma, Fukushima, Yumi, Segawa, Takuya, Motoshima, Takanobu, Murakami, Yoji, Yamaguchi, Takahiro, Sugiyama, Yutaka, Kamba, Tomomi

“…Introduction Subcapsular renal hematoma after ureterorenoscopy using a holmium yttrium‐aluminum‐garnet laser is a rare complication. We experienced a case of…”
Get full text

Clear cell carcinoma of the seminal vesicle in a young adult by Murakami, Hidetoshi, Motoshima, Takanobu, Kurahashi, Ryoma, Murakami, Yoji, Sugiyama, Yutaka, Yamaguchi, Takahiro, Yatsuda, Junji, Asato, Tsuguharu, Mikami, Yoshiki, Kamba, Tomomi

“…Introduction Most seminal vesicle malignancies are secondary to prostate or bladder cancer. Herein, we report a case of primary clear cell carcinoma of the…”
Get full text

Efficacy of avelumab plus axitinib for advanced renal cell carcinoma as late-line therapy: A case report by Uekawa, Ayano, Kurahashi, Ryoma, Motoshima, Takanobu, Murakami, Yoji, Yatsuda, Junji, Kamba, Tomomi

“…A 46-year-old man developed a right renal tumor with multiple lung and hilar lymph node metastases. Laparoscopic radical nephrectomy was performed, and clear…”
Get full text

Pembrolizumab for treating advanced urothelial carcinoma in patients with impaired performance status: Analysis of a Japanese nationwide cohort by Ito, Katsuhiro, Kobayashi, Takashi, Kojima, Takahiro, Hikami, Kensuke, Yamada, Takeshi, Ogawa, Kosuke, Nakamura, Kenji, Sassa, Naoto, Yokomizo, Akira, Abe, Takashige, Tsuchihashi, Kazunari, Tatarano, Shuichi, Inokuchi, Junichi, Tomida, Ryotaro, Fujiwara, Maki, Takahashi, Atsushi, Matsumoto, Kazumasa, Shimizu, Kosuke, Araki, Hiromasa, Kurahashi, Ryoma, Osaki, Yu, Tashiro, Yu, Uegaki, Masayuki, Ogawa, Osamu, Kitamura, Hiroshi, Nishiyama, Hiroyuki

“…Background The benefits of pembrolizumab in patients with advanced urothelial carcinoma (UC) and impaired performance status (PS) remain unknown. This study…”
Get full text

t(6; 11) renal cell carcinoma. A case report successfully diagnosed by using fluorescence in situ hybridization by Nishizawa, Hidekazu, Baba, Masaya, Furuya, Mitsuko, Kato, Ikuma, Kurahashi, Ryoma, Honda, Yumi, Mikami, Yoshiki, Nagashima, Yoji, Eto, Masatoshi, Kamba, Tomomi

“…Introduction Definitive diagnosis of translocation renal cell carcinoma is challenging. We herein experienced a case of translocation(6;11) renal cell…”
Get full text

Remarkable antitumor effect of nivolumab in a patient with metastatic renal cell carcinoma previously treated with a peptide‐based vaccine by Kurahashi, Ryoma, Motoshima, Takanobu, Fukushima, Yumi, Murakami, Yoji, Yatsuda, Junji, Yamaguchi, Takahiro, Sugiyama, Yutaka, Fukushima, Satoshi, Komohara, Yoshihiro, Suekane, Shigetaka, Kamba, Tomomi

“…Introduction The safety and efficacy of combination therapy comprising immune checkpoint inhibitors and cancer‐specific peptide vaccines have not yet been…”
Get full text

Successful Management for Refractory Non-Seminomatous Testicular Cancer with Retroperitoneal Lymph Node, Liver, Lung and Brain Metastases : A Case Report by Yamanaka, Kotaro, Yamaguchi, Takahiro, Kurahashi, Ryoma, Motoshima, Takanobu, Murakami, Youji, Yatsuda, Junji, Sugiyama, Yutaka, Nishi, Kazuhiko, Kamba, Tomomi

Get full text

A retrospective study of prognostic factors and prostate-specific antigen dynamics in Japanese patients with metastatic hormone-sensitive prostate cancer who received combined androgen blockade therapy with bicalutamide by Tashiro, Yu, Akamatsu, Shusuke, Ueno, Kentaro, Kamoto, Toshiyuki, Terada, Naoki, Hida, Takuya, Kurahashi, Ryoma, Kamba, Tomomi, Saito, Atsushi, Lee, Takumi, Morita, Satoshi, Kobayashi, Takashi

“…Background This retrospective observational study explored the therapeutic potential of combined androgen blockade (CAB) with bicalutamide (Bic-CAB) as an…”
Get full text

Predictive value of CXCL10 for the occurrence of immune‐related adverse events in patient with renal cell carcinoma by Miura, Yuji, Motoshima, Takanobu, Anami, Toshiki, Yano, Hiromu, Mito, Remi, Pan, Cheng, Urakami, Shinji, Kinowaki, Keiichi, Tsukamoto, Hirotake, Kurahashi, Ryoma, Murakami, Yoji, Yatsuda, Junji, Fujiwara, Yukio, Kamba, Tomomi, Komohara, Yoshihiro

“…Immune checkpoint inhibitors (ICIs) have recently improved the prognosis of various cancers. By contrast, some immune‐related adverse events (irAEs) caused by…”
Get full text