Search Results - "Kuphal, Silke"

AP-1/c-Jun transcription factors: Regulation and function in malignant melanoma by Kappelmann, Melanie, Bosserhoff, Anja, Kuphal, Silke

“…Malignant melanoma is an aggressive form of skin cancer with an increasing incidence worldwide. One way to address the pathology of the disease is through…”
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Loss of Gene Information: Discrepancies between RNA Sequencing, cDNA Microarray, and qRT-PCR by Rachinger, Nicole, Fischer, Stefan, Böhme, Ines, Linck-Paulus, Lisa, Kuphal, Silke, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K.

“…Molecular analyses of normal and diseased cells give insight into changes in gene expression and help in understanding the background of pathophysiological…”
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Recent progress in understanding the pathology of malignant melanoma by Kuphal, Silke, Bosserhoff, Anja

“…Recently, several important findings on melanoma development and progression have accelerated progress towards a molecular understanding of melanoma biology…”
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NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma by Devitt, Lucia, Westphal, Dana, Pieger, Katharina, Schneider, Nadja, Bosserhoff, Anja Katrin, Kuphal, Silke

“…Melanoma is a highly heterogeneous cancer, in which frequent changes in activation of signaling pathways lead to a high adaptability to ever changing tumor…”
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Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence by Kluge, Viola, Kappelmann-Fenzl, Melanie, Fischer, Stefan, Zimmermann, Tom, Pommer, Michaela, Kuphal, Silke, Bosserhoff, Anja-Katrin

“…Oncogene-induced senescence (OIS) is an important process that suppresses tumor development, but the molecular mechanisms of OIS are still under investigation…”
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Loss of miR-101-3p in melanoma stabilizes genomic integrity, leading to cell death prevention by Lämmerhirt, Lisa, Kappelmann-Fenzl, Melanie, Fischer, Stefan, Meier, Paula, Staebler, Sebastian, Kuphal, Silke, Bosserhoff, Anja-Katrin

“…Malignant melanoma remains the most lethal form of skin cancer, exhibiting poor prognosis after forming distant metastasis. Owing to their potential…”
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Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma by Massoumi, Ramin, Kuphal, Silke, Hellerbrand, Claus, Haas, Bodo, Wild, Peter, Spruss, Thilo, Pfeifer, Alexander, Fässler, Reinhard, Bosserhoff, Anja K

“…High malignancy and early metastasis are hallmarks of melanoma. Here, we report that the transcription factor Snail1 inhibits expression of the tumor…”
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Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma by Kuphal, Silke, Wallner, Susanne, Bosserhoff, Anja K.

“…Leukemia inhibitory factor (LIF) signaling regulates cellular processes to maintain the self-renewal and pluripotency of embryonic stem (ES) cells. Independent…”
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Role of melanoma inhibitory activity in melanocyte senescence by Feuerer, Lena, Lamm, Susanne, Henz, Ingmar, Kappelmann‐Fenzl, Melanie, Haferkamp, Sebastian, Meierjohann, Svenja, Hellerbrand, Claus, Kuphal, Silke, Bosserhoff, Anja Katrin

“…The protein melanoma inhibitory activity (MIA) is known to be expressed in melanoma and to support melanoma progression. Interestingly, previous studies also…”
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Amphiregulin Regulates Melanocytic Senescence by Pommer, Michaela, Kuphal, Silke, Bosserhoff, Anja K

“…Oncogene-induced senescence (OIS) is a decisive process to suppress tumor development, but the molecular details of OIS are still under investigation. Using an…”
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Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation by Blau, Lior, Knirsh, Revital, Ben-Dror, Iris, Oren, Sivan, Kuphal, Silke, Hau, Peter, Proescholdt, Martin, Bosserhoff, Anja-Katrin, Vardimon, Lily

“…Although the protooncogene c-Jun plays a critical role in cell proliferation, cell death, and malignant transformation, DNA microarray screens have identified…”
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HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma by Heppt, Markus V, Wessely, Anja, Hornig, Eva, Kammerbauer, Claudia, Graf, Saskia A, Besch, Robert, French, Lars E, Matthies, Alexander, Kuphal, Silke, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K, Berking, Carola

“…The neural crest transcription factor BRN3A is essential for the proliferation and survival of melanoma cells. It is frequently expressed in melanoma but not…”
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Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma by Lämmerhirt, Lisa, Kappelmann-Fenzl, Melanie, Fischer, Stefan, Pommer, Michaela, Zimmermann, Tom, Kluge, Viola, Matthies, Alexander, Kuphal, Silke, Bosserhoff, Anja Katrin

“…Modifications in nuclear structures of cells are implicated in several diseases including cancer. They result in changes in nuclear activity, structural…”
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Nucleosome Remodeler SNF2L Suppresses Cell Proliferation and Migration and Attenuates Wnt Signaling by Eckey, Maren, Kuphal, Silke, Straub, Tobias, Rümmele, Petra, Kremmer, Elisabeth, Bosserhoff, Anja K, Becker, Peter B

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Alpha-Synuclein and Its Role in Melanocytes by Rachinger, Nicole, Mittag, Nora, Böhme-Schäfer, Ines, Xiang, Wei, Kuphal, Silke, Bosserhoff, Anja K.

“…Pigmentation is an important process in skin physiology and skin diseases and presumably also plays a role in Parkinson’s disease (PD). In PD, alpha-Synuclein…”
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Melanoblasts in culture as an in vitro system to determine molecular changes in melanoma by Bosserhoff, Anja Katrin, Ellmann, Lisa, Kuphal, Silke

“…:  Many consolidated findings have revealed that cancer formation resembles events of embryonic development. In particular, the network of transcription…”
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A single flavoprotein, AppA, integrates both redox and light signals in Rhodobacter sphaeroides by Braatsch, Stephan, Gomelsky, Mark, Kuphal, Silke, Klug, Gabriele

“…Summary Anoxygenic photosynthetic proteobacteria exhibit various light responses, including changing levels of expression of photosynthesis genes. However, the…”
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BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells by Ellmann, Lisa, Joshi, Manjunath B, Resink, Therese J, Bosserhoff, Anja K, Kuphal, Silke

“…T-cadherin (cadherin 13, H-cadherin, gene name CDH13) has been proposed to act as a tumor-suppressor gene as its expression is significantly diminished in…”
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Loss of nephronectin promotes tumor progression in malignant melanoma by Kuphal, Silke, Wallner, Susanne, Bosserhoff, Anja K.

“…Nephronectin (POEM) was originally identified as a factor involved in tissue morphogenesis. POEM has several characteristics of a matrix protein including an…”
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Selenium-binding protein 1 is down-regulated in malignant melanoma by Schott, Mandy, de Jel, Miriam M., Engelmann, Julia C., Renner, Philipp, Geissler, Edward K., Bosserhoff, Anja K., Kuphal, Silke

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