Search Results - "Kupferwasser, Deborah"

Predictors of seropositivity to SARS-CoV-2 among employees at a large urban medical center by Kupferwasser, Deborah, Flores, Evelyn A, Merino, Prudencio, Tran, Donna Phan, Liu, Honghu, Huang, Yilan, Bolaris, Michael, Nguyen, Megan H, Gonzales, Mildred, Da Silva, Wellington, Astorga-Cook, Leslie, Abueg, Angel, Mason, Holli, Miller, Loren G

“…Before SARS-CoV-2 vaccination availability, medical center employees were at high risk of COVID-19. However, risk factors for SARS-CoV-2 infection in medical…”
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Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection by Yeaman, Michael R, Filler, Scott G, Chaili, Siyang, Barr, Kevin, Wang, Huiyuan, Kupferwasser, Deborah, Hennessey, Jr, John P, Fu, Yue, Schmidt, Clint S, Edwards, Jr, John E, Xiong, Yan Q, Ibrahim, Ashraf S

“…Significance Staphylococcus aureus is an opportunistic pathogen of the normal human flora. It is among the most frequent causes of cutaneous abscesses, leading…”
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Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus by Chan, Liana C, Chaili, Siyang, Filler, Scott G, Barr, Kevin, Wang, Huiyuan, Kupferwasser, Deborah, Edwards, Jr, John E, Xiong, Yan Q, Ibrahim, Ashraf S, Miller, Lloyd S, Schmidt, Clint S, Hennessey, Jr, John P, Yeaman, Michael R

“…Staphylococcus aureus is the leading cause of skin and skin structure infections (SSSI) in humans. Moreover, the high frequency of recurring SSSI due to S…”
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Selective Reciprocity in Antimicrobial Activity versus Cytotoxicity of hBD-2 and Crotamine by Yount, Nannette Y., Kupferwasser, Deborah, Spisni, Alberto, Dutz, Stephen M., Ramjan, Zachary H., Sharma, Shantanu, Waring, Alan J., Yeaman, Michael R., Kaback, H. Ronald

“…Recent discoveries suggest cysteine-stabilized toxins and antimicrobial peptides have structure-activity parallels derived by common ancestry. Here, human…”
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Longitudinal analysis of SARS-CoV-2 infection and vaccination in the LA-SPARTA cohort reveals increased risk of infection in vaccinated Hispanic participants by Jenkins, Meagan M, Phan Tran, Donna, Flores, Evelyn A, Kupferwasser, Deborah, Pickering, Harry, Zheng, Ying, Gjertson, David W, Ross, Ted M, Schaenman, Joanna M, Miller, Loren G, Yeaman, Michael R, Reed, Elaine F

“…SARS-CoV-2 is the etiologic agent of coronavirus disease 2019 (COVID-19). Questions remain regarding correlates of risk and immune protection against COVID-19…”
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Effectiveness of empiric carbapenem versus non-carbapenem therapy for extended-spectrum β-lactamase producing Enterobacterales infections in non-intensive care unit patients: a real-world investigation in a hospital with high-prevalence of extended-spectrum β-lactamase producing Enterobacterales by Kang, Amy Y, Elkomos, Mary, Pham, Danny, Guerrero, Michelle, Kupferwasser, Deborah, Miller, Loren G

“…To investigate whether empiric carbapenem therapy, compared to empiric non-carbapenem therapy, was associated with improved clinical outcomes among…”
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Characterization of COVID-19 Vaccine Hesitancy Among Essential Workforce Members of a Large Safety Net Urban Medical Center by Kupferwasser, Deborah, Flores, Evelyn A., Merino, Prudencio, Phan Tran, Donna, Bolaris, Michael, Gonzales, Mildred, Nguyen, Megan H., Balo, Arlene, Abueg, Angel, Da Silva, Wellington, Astorga-Cook, Leslie, Liu, Honghu, Mason, Holli, Freund, Deborah, Nightingale, Judi, Orr, Jay, Xie, Bin, Miller, Loren G.

“…Objectives: Vaccine hesitancy among essential workers remains a significant public health challenge. We examined psychological constructs of perceived…”
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Modular determinants of antimicrobial activity in platelet factor-4 family kinocidins by Yeaman, Michael R., Yount, Nannette Y., Waring, Alan J., Gank, Kimberly D., Kupferwasser, Deborah, Wiese, Robert, Bayer, Arnold S., Welch, William H.

“…Mammalian platelets contain an array of antimicrobial peptides, termed platelet microbicidal proteins (PMPs). Human and rabbit PMPs include known chemokines,…”
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Platelet Antistaphylococcal Responses Occur through P2X₁ and P2Y₁₂ Receptor-Induced Activation and Kinocidin Release by Trier, Darin A, Gank, Kimberly D, Kupferwasser, Deborah, Yount, Nannette Y, French, William J, Michelson, Alan D, Kupferwasser, Leon I, Xiong, Yan Q, Bayer, Arnold S, Yeaman, Michael R

“…Platelets (PLTs) act in antimicrobial host defense by releasing PLT microbicidal proteins (PMPs) or PLT kinocidins (PKs). Receptors mediating staphylocidal…”
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Context mediates antimicrobial efficacy of kinocidin congener peptide RP-1 by Yount, Nannette Y, Cohen, Samuel E, Kupferwasser, Deborah, Waring, Alan J, Ruchala, Piotr, Sharma, Shantanu, Wasserman, Karlman, Jung, Chun-Ling, Yeaman, Michael R

“…Structure-mechanism relationships are key determinants of host defense peptide efficacy. These relationships are influenced by anatomic, physiologic and…”
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390. Sociodemographic Factors Associated With Patients Hospitalized for Coccidioidomycosis in California and Arizona, State Inpatient Database 2005–2011 by Kupferwasser, Deborah, Miller, Loren

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Characterization of COVID-19 Vaccine Hesitancy among Essential Workforce Members of a Large Urban Hospital in Los Angeles, CA by Kupferwasser, Deborah

“…Background: Essential workforce members such as those employed by hospitals were among the first populations to be offered the Emergency Use Authorized…”
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Skin and soft tissue infection incidence before and during the COVID-19 pandemic by Merino, Prudencio, Kupferwasser, Deborah, Flores, Evelyn A., Phan Tran, Donna, Ortega, Abisay, Miller, Loren G.

“…Skin and Soft Tissue Infections (SSTIs) are common bacterial infections. We hypothesized that due to the COVID-19 pandemic, SSTI rates would significantly…”
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Longitudinal analysis of the LA-SPARTA cohort of high-risk individuals after SARS-CoV-2 infection and vaccination by Jenkins, Meagan M, Tran, Donna Phan, Flores, Evelyn A, Kupferwasser, Deborah, Pickering, Harry, Zheng, Ying, Gjertson, David W, Ross, Ted M, Schaenman, Joanna M, Miller, Loren G, Yeaman, Michael R, Reed, Elaine F

“…Abstract Questions remain regarding correlates of risk and immune protection against SARS-CoV-2 infection and vaccination response. Thus, we prospectively…”
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1817. Skin and Soft Tissue Infection Incidence Before and During the COVID-19 Pandemic at A Large Safety Net Healthcare System by Merino, Prudencio, Kupferwasser, Deborah, Flores, Evelyn A, Tran, Donna Phan, Ortega, Abisay, Miller, Loren G

“…Abstract Background Skin and Soft Tissue Infections (SSTIs) are one of the most common bacterial infections that drive persons to seek medical care. We…”
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2905. Development of a Desirability of Outcome Ranking (DOOR) for Skin Infection Clinical Trials by Miller, Loren G, Phan Tran, Donna, Flores, Evelyn A, Liu, Honghu, Weidmer, Beverly A, Kupferwasser, Deborah, Boyle, Mary G, Williams, Pluscedia, Zhou, Linyu, Huang, Yilan, Evans, Scott R, Fritz, Stephanie A

“…Abstract Background Infectious disease clinical trials treatment outcomes have almost exclusively been dichotomized into cure and failure. The novel…”
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387. Predictors of Seropositivity to SARS-CoV-2 Among Workforce Members at a Large Urban Medical Center by Flores, Evelyn A, Kupferwasser, Deborah, Merino, Prudencio, Tran, Donna Phan, Liu, Honghu, Huang, Yilan, Bolaris, Michael, Nguyen, Megan H, Gonzalez, Mildred, Da Silva, Wellington, Astorga-Cook, Leslie, Abueg, Angel, Mason, Holli, Miller, Loren G

“…Abstract Background Prior to SARS-CoV-2 vaccination availability, medical centers workers were at significant COVID-19 (COVID) infection risk. As part of a…”
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Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection by Yeaman, Michael R., Filler, Scott G., Chaili, Siyang, Barr, Kevin, Wang, Huiyuan, Kupferwasser, Deborah, Hennessey, John P., Fu, Yue, Schmidt, Clint S., Edwards, John E., Xiong, Yan Q., Ibrahim, Ashraf S.

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Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus by Kupferwasser, Leon Iri, Yeaman, Michael R, Nast, Cynthia C, Kupferwasser, Deborah, Xiong, Yan-Qiong, Palma, Marco, Cheung, Ambrose L, Bayer, Arnold S

“…Aspirin has been previously shown to reduce the in vivo virulence of Staphylococcus aureus in experimental endocarditis, through antiplatelet and antimicrobial…”
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Structural correlates of antimicrobial efficacy in IL-8 and related human kinocidins by Yount, Nannette Y., Waring, Alan J., Gank, Kimberly D., Welch, William H., Kupferwasser, Deborah, Yeaman, Michael R.

“…Chemokines are small (8–12 kDa) effector proteins that potentiate leukocyte chemonavigation. Beyond this role, certain chemokines have direct antimicrobial…”
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