Search Results - "Kupcova, Viera"
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Overview of the Pathogenesis, Genetic, and Non-Invasive Clinical, Biochemical, and Scoring Methods in the Assessment of NAFLD
Published in International journal of environmental research and public health (24-09-2019)“…Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. It represents a range of disorders, including simple steatosis,…”
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The Effect of Various Degrees of Renal or Hepatic Impairment on the Pharmacokinetic Properties of Once-Weekly Insulin Icodec
Published in Clinical pharmacokinetics (01-06-2024)“…Background and Objective Icodec is a once-weekly insulin being developed to provide basal insulin coverage in diabetes mellitus. This study evaluated the…”
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3
Chronic hepatitis C virus infection in the Czech Republic and Slovakia: an analysis of patient and virus characteristics
Published in International journal of public health (01-12-2020)“…Objectives The MOSAIC study gathered data on chronic hepatitis C virus (HCV) infection and its treatment in various countries worldwide. Here we summarise…”
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Effect of Renal or Hepatic Impairment on the Pharmacokinetics of Mirabegron
Published in Clinical drug investigation (2013)“…Background and Objectives Mirabegron, a selective β3-adrenoceptor agonist for the treatment of overactive bladder (OAB), is eliminated by renal and metabolic…”
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5
Questionnaire for risk factors of alcoholic and nonalcoholic fatty liver disease
Published in Bratislavské lékarské listy (01-01-2022)“…OBJECTIVESNon-communicable diseases are estimated to account for 90 % of total deaths and 19 % of premature deaths in Slovakia. Major preventable risk factors…”
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Ritonavir-boosted danoprevir-based regimens in treatment-naive and prior null responders with HCV genotype 1 or 4 and compensated cirrhosis
Published in Hepatology international (01-05-2016)“…Background and aim Effective and safe antiviral treatment regimens are needed for patients with chronic hepatitis C (CHC) and cirrhosis. Methods An…”
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Pharmacokinetics, Safety, and Tolerability of Oral Semaglutide in Subjects With Hepatic Impairment
Published in Journal of clinical pharmacology (01-10-2018)“…Semaglutide is a human glucagon‐like peptide‐1 analog that has been co‐formulated with the absorption enhancer, sodium N‐(8‐[2‐hydroxybenzoyl] amino)…”
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The Effect of Hepatic Impairment on the Pharmacokinetics of Intravenously Administered Felcisetrag (TAK‐954)
Published in Journal of clinical pharmacology (01-08-2022)“…Felcisetrag (formerly known as TAK‐954) is a selective serotonin receptor agonist under investigation for use in patients with postoperative gastrointestinal…”
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Insulin Degludec: Pharmacokinetic Properties in Subjects with Hepatic Impairment
Published in Clinical drug investigation (01-02-2014)“…Background and Objective Insulin degludec is a basal insulin with a slow and distinct absorption mechanism resulting in an ultra-long, flat, and stable…”
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Su1502 THE ROLE OF CELL-FREE DNA IN THE PATHOGENESIS OF ACUTE AND CHRONIC LIVER DISEASE
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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Pharmacokinetics and tolerability of semaglutide in people with hepatic impairment
Published in Diabetes, obesity & metabolism (01-04-2018)“…Aims To investigate whether the pharmacokinetic characteristics of semaglutide were altered in people with hepatic impairment, assessed using Child–Pugh…”
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Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients
Published in Antiviral research (01-11-2014)“…•We present the long-term safety and efficacy outcome of patients treated with anti-miR therapy.•No long-term safety issues were observed among…”
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Obesity, elevated levels of fasting plasma glucose and type 2 diabetes are associated with aortic stiffness
Published in Bratislavské lékarské listy (2023)“…Obesity and metabolic syndrome (MetS) are associated with structural and functional vascular abnormalities. MetS and its components may increase arterial…”
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Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis – amelioration by liver transplantation
Published in Journal of hepatology (2002)“…Background/Aims : Modification by advanced glycation renders macromolecules susceptible to elimination in the liver via scavenger receptors. Thus, in advanced…”
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The effect of severe hepatic impairment on the pharmacokinetics and haematological response of C.E.R.A
Published in Current medical research and opinion (01-07-2008)“…ABSTRACT Aim: To examine the effect of severe hepatic impairment (HI) on the pharmacokinetics (PK) and pharmacodynamics (PD) of the continuous erythropoietin…”
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809-P: The Effect of Various Degrees of Hepatic Impairment on the Pharmacokinetic Characteristics of Once-Weekly Insulin Icodec
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Insulin icodec is a novel basal insulin being developed for once-weekly administration. This study investigated if the pharmacokinetic characteristics of…”
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Serum butyrylcholinesterase/HDL-cholesterol ratio and atherogenic index of plasma in patients with fatty liver disease
Published in Vnitřní lékar̆stvĭ (21-04-2021)“…Cardiovascular diseases on an atherosclerotic basis are a serious health problem. Atherosclerosis is a multifactorial pathological process with complex…”
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Comparison of serum hyaluronic acid and N-acetylglucosaminidase activity in patients with chronic hepatitis
Published in Journal of hepatology (01-04-2002)Get full text
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Advanced glykation end products in patients with liver cirrhosis before and after liver transplantation
Published in Journal of hepatology (01-04-2002)Get full text
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Serum hyaluronic acid as a marker of hepatic fibrosis in patients with chronic liver diseases
Published in Journal of hepatology (01-04-2002)Get full text
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