Search Results - "Kupai, Krisztina"
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1
Experimental Diabetes Mellitus in Different Animal Models
Published in Journal of diabetes research (01-01-2016)“…Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology and target identification and in the…”
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2
Bone Loss in Diabetes Mellitus: Diaporosis
Published in International journal of molecular sciences (02-07-2024)“…The objective of this review is to examine the connection between osteoporosis and diabetes, compare the underlying causes of osteoporosis in various forms of…”
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3
Investigation of H2S Donor Treatment on Neutrophil Extracellular Traps in Experimental Colitis
Published in International journal of molecular sciences (01-12-2021)“…Inflammatory bowel diseases (IBD) are chronic, immune-mediated disorders, which affect the gastrointestinal tract with intermittent ulceration. It is…”
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4
Role of physical activity and cardiorespiratory fitness in metabolically healthy obesity: a narrative review
Published in BMJ Open Sport & Exercise Medicine (05-12-2022)“…Obesity has been associated with a multitude of metabolic disorders, often clustering with risk factors of cardiovascular disease and type 2 diabetes mellitus,…”
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5
Novel Potentials of the DPP-4 Inhibitor Sitagliptin against Ischemia-Reperfusion (I/R) Injury in Rat Ex-Vivo Heart Model
Published in International journal of molecular sciences (18-10-2018)“…Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of oral anti-diabetic drugs, implicated in pleiotropic secondary cardioprotective effects. The aim of the…”
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6
Lessons on the Sigma-1 Receptor in TNBS-Induced Rat Colitis: Modulation of the UCHL-1, IL-6 Pathway
Published in International journal of molecular sciences (05-06-2020)“…Inflammatory Bowel Disease (IBD) is an autoimmune ailment of the gastrointestinal (GI) tract, which is characterized by enhanced activation of proinflammatory…”
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7
A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and "Medical Cannabinoids"
Published in International journal of molecular sciences (20-11-2020)“…Endocannabinoids and their receptors are present in the cardiovascular system; however, their actions under different pathological conditions remain…”
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8
New Metabolic Influencer on Oxytocin Release: The Ghrelin
Published in Molecules (Basel, Switzerland) (18-02-2019)“…The hypothalamic⁻pituitary axis by secreting neuropeptides plays a key role in metabolic homeostasis. In light of the metabolic regulation, oxytocin is a…”
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9
Recent Progress in the Diagnosis and Management of Type 2 Diabetes Mellitus in the Era of COVID-19 and Single Cell Multi-Omics Technologies
Published in Life (Basel, Switzerland) (08-08-2022)“…Type 2 diabetes mellitus (T2DM) is one of the world's leading causes of death and life-threatening conditions. Therefore, we review the complex vicious circle…”
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10
Cholesterol diet leads to attenuation of ischemic preconditioning-induced cardiac protection: the role of connexin 43
Published in American journal of physiology. Heart and circulatory physiology (01-05-2011)“…Cardioprotection by ischemic preconditioning (IP) was abolished in connexin 43 (Cx43)-deficient mice due to loss of Cx43 located in mitochondria rather than at…”
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11
Paclitaxel Protects against Isoproterenol-Induced Damage in Rat Myocardium: Its Heme-Oxygenase Mediated Role in Cardiovascular Research
Published in Antioxidants (20-05-2023)“…(1) Background: In cardiovascular applications, paclitaxel inhibits smooth muscle cell proliferation and migration and significantly reduces the occurrence of…”
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12
Sigma-1 Receptor Engages an Anti-Inflammatory and Antioxidant Feedback Loop Mediated by Peroxiredoxin in Experimental Colitis
Published in Antioxidants (01-11-2020)“…Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory condition of the gastrointestinal…”
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13
Potential Implications of Rimonabant on Age-Related Oxidative Stress and Inflammation
Published in Antioxidants (14-01-2022)“…Over the last decades, growing interest has turned to preventive and therapeutic approaches for achieving successful aging. Oxidative stress and inflammation…”
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14
Spotlight on a New Heme Oxygenase Pathway: Testosterone-Induced Shifts in Cardiac Oxidant/Antioxidant Status
Published in Antioxidants (07-08-2019)“…A low testosterone level contributes to the development of oxidative damages; however, the cardiovascular effects of exogenous hormone therapy are not well…”
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15
H2S confers colonoprotection against TNBS-induced colitis by HO-1 upregulation in rats
Published in Inflammopharmacology (01-04-2018)“…Hydrogen sulfide (H 2 S) is an endogenous mediator that contributes to many important physiological processes including vasodilation and vascular smooth muscle…”
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16
Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection
Published in Frontiers in pharmacology (05-04-2018)“…The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted…”
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17
Distinct Approaches of Raloxifene: Its Far-Reaching Beneficial Effects Implicating the HO-System
Published in Biomolecules (Basel, Switzerland) (28-02-2020)“…Selective estrogen receptor modulators (SERMs) were discovered in the mid-1900s in connection with estrogen-related pathological conditions. They were…”
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18
Dietary red palm oil supplementation reduces myocardial infarct size in an isolated perfused rat heart model
Published in Lipids in health and disease (18-06-2010)“…Recent studies have shown that dietary red palm oil (RPO) supplementation improves functional recovery following ischaemia/reperfusion in isolated hearts. The…”
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19
Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats
Published in Lipids in health and disease (20-06-2011)“…The effect of red palm oil (RPO) supplementation on infarct size after ischaemia/reperfusion in a cholesterol enriched diet-induced hyperlipidemic animal model…”
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20
MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart
Published in Journal of molecular and cellular cardiology (01-09-2013)“…Abstract Diet-induced hypercholesterolemia leads to oxidative/nitrative stress and subsequent myocardial dysfunction. However, the regulatory role of microRNAs…”
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