Search Results - "Kuo, Jay J"

The key role of NLRP3 and STING in APOL1-associated podocytopathy by Wu, Junnan, Raman, Archana, Coffey, Nathan J, Sheng, Xin, Wahba, Joseph, Seasock, Matthew J, Ma, Ziyuan, Beckerman, Pazit, Laczkó, Dorottya, Palmer, Matthew B, Kopp, Jeffrey B, Kuo, Jay J, Pullen, Steven S, Boustany-Kari, Carine M, Linkermann, Andreas, Susztak, Katalin

“…Coding variants in apolipoprotein L1 (APOL1), termed G1 and G2, can explain most excess kidney disease risk in African Americans; however, the molecular…”
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In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease by Lin, Brian Leei, Matera, Damian, Doerner, Julia F., Zheng, Nan, del Camino, Donato, Mishra, Sumita, Bian, Hong, Zeveleva, Svetlana, Zhen, Xiaoguang, Blair, Nathaniel T., Chong, Jayhong A., Hessler, David P., Bedja, Djahida, Zhu, Guangshuo, Muller, Grace K., Ranek, Mark J., Pantages, Lynn, McFarland, Mary, Netherton, Matthew R., Berry, Angela, Wong, Diane, Rast, Georg, Qian, Hu Sheng, Weldon, Steven M., Kuo, Jay J., Sauer, Achim, Sarko, Chris, Moran, Magdalene M., Kass, David A., Pullen, Steven S.

“…Transient receptor potential canonical type 6 (TRPC6) is a non-selective receptor-operated cation channel that regulates reactive fibrosis and growth…”
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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis by Muto, Yoshiharu, Dixon, Eryn E., Yoshimura, Yasuhiro, Wu, Haojia, Omachi, Kohei, Ledru, Nicolas, Wilson, Parker C., King, Andrew J., Eric Olson, N., Gunawan, Marvin G., Kuo, Jay J., Cox, Jennifer H., Miner, Jeffrey H., Seliger, Stephen L., Woodward, Owen M., Welling, Paul A., Watnick, Terry J., Humphreys, Benjamin D.

“…Autosomal dominant polycystic kidney disease (ADPKD) is the leading genetic cause of end stage renal disease characterized by progressive expansion of kidney…”
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Role of Hypothalamic Melanocortin 3/4-Receptors in Mediating Chronic Cardiovascular, Renal, and Metabolic Actions of Leptin by da Silva, Alexandre A, Kuo, Jay J, Hall, John E

“…The present study examined whether blockade of melanocortin receptors subtypes 3 and 4 (MC3/4-R) inhibits chronic cardiovascular and dietary responses to…”
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Chronic Cardiovascular and Renal Actions of Leptin: Role of Adrenergic Activity by Carlyle, Megan, Jones, Oscar B, Kuo, Jay J, Hall, John E

“…ABSTRACT—This study was designed to determine the role of changes in adrenergic activity in mediating the chronic cardiovascular, renal, and metabolic actions…”
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Hypothalamic Melanocortin Receptors and Chronic Regulation of Arterial Pressure and Renal Function by Kuo, Jay J, Silva, Alexandre A, Hall, John E

“…ABSTRACT—This study examined control of cardiovascular and renal function during chronic melanocortin-3/4 receptor (MC3/4-R) activation or inhibition. Arterial…”
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Obesity-associated hypertension and kidney disease by Hall, John E, Kuo, Jay J, da Silva, Alexandre A, de Paula, Rogerio B, Liu, Jiankang, Tallam, Lakshmi

“…PURPOSE OF REVIEWThe worldwide prevalence of obesity and its associated metabolic and cardiovascular disorders has risen dramatically during the past two…”
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Inhibition of NO Synthesis Enhances Chronic Cardiovascular and Renal Actions of Leptin by Kuo, Jay J, Jones, Oscar B, Hall, John E

“…Acute studies suggest that leptin has pressor and depressor actions, including stimulation of sympathetic activity as well as increased release of NO from the…”
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Role of Adrenergic Activity in Pressor Responses to Chronic Melanocortin Receptor Activation by Kuo, Jay J, da Silva, Alexandre A, Tallam, Lakshmi S, Hall, John E

“…ABSTRACT—Acute studies have shown that MC3/4-R stimulation increases sympathetic activity, but the role of adrenergic activation in mediating the…”
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Impact of the obesity epidemic on hypertension and renal disease by Hall, John E, Jones, Daniel W, Kuo, Jay J, da Silva, Alexandre, Tallam, Lakshmi S, Liu, Jiankang

“…Excess weight gain is a major cause of increased blood pressure in most patients with essential hypertension, and also greatly increases the risk for renal…”
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Is obesity a major cause of chronic kidney disease? by Hall, John E, Henegar, Jeffrey R, Dwyer, Terry M, Liu, Jiankang, Da Silva, Alexandre A, Kuo, Jay J, Tallam, Lakshmi

“…Excess weight gain is a major risk factor for essential hypertension and for end-stage renal disease (ESRD). Obesity raises blood pressure by increasing renal…”
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Does Obesity Induce Resistance to the Long-Term Cardiovascular and Metabolic Actions of Melanocortin 3/4 Receptor Activation? by da Silva, Alexandre A, Kuo, Jay J, Tallam, Lakshmi S, Liu, Jiankang, Hall, John E

“…Previous studies suggest that blockade of melanocortin 3 and 4 receptors (MC3/4-R) markedly attenuates the chronic hypertensive effects of leptin. Although…”
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Role of Endothelin-1 in Blood Pressure Regulation in a Rat Model of Visceral Obesity and Hypertension by da Silva, Alexandre A, Kuo, Jay J, Tallam, Lakshmi S, Hall, John E

“…ABSTRACT—Endothelial dysfunction has been suggested to play an important role in the development of obesity-induced hypertension. Because endothelin release…”
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Cardiovascular, Renal, and Metabolic Responses to Chronic Central Administration of Agouti-Related Peptide by Tallam, Lakshmi S, Kuo, Jay J, da Silva, Alexandre A, Hall, John E

“…Although excess hypothalamic agouti-related peptide (AGRP), an endogenous antagonist of the melanocortin 3/4 receptor, causes hyperphagia and obesity, its role…”
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Chronic cardiovascular and renal actions of leptin during hyperinsulinemia by Kuo, Jay J, Jones, O Barrett, Hall, John E

“…Hyperinsulinemia and hyperleptinemia occur concurrently in obese subjects, and both have been suggested to mediate increased blood pressure associated with…”
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Role of Nitric Oxide in Modulating the Chronic Cardiovascular and Renal Actions of Leptin by Kuo, Jay J, Jones, Oscar B, Hall, John E

“…Abstract only 64 Acute studies suggest that leptin has pressor and depressor actions, including stimulation of sympathetic activity as well as increased…”
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INCREASED KALLIKREIN ACTIVITY IN THE RABBIT RENAL VASCULATURE DURING LOW SODIUM INTAKE by Kuo, Jay J., Zimmerman, Ben G.

“…SUMMARY 1. Vascular tissue has been shown to possess a kallikrein ‐kinin system that may participate in the kinin‐mediated increase in renal sodium excretion…”
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Prolog to : discretization and solution of elliptic PDEs : a digital signal processing approach by WATSON, G. F, JAY KUO, C.-C. J, LEVY, B. C

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