Search Results - "Kuo, Christin S."

Formation of a Neurosensory Organ by Epithelial Cell Slithering by Kuo, Christin S., Krasnow, Mark A.

“…Epithelial cells are normally stably anchored, maintaining their relative positions and association with the basement membrane. Developmental rearrangements…”
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A molecular cell atlas of the human lung from single-cell RNA sequencing by Travaglini, Kyle J., Nabhan, Ahmad N., Penland, Lolita, Sinha, Rahul, Gillich, Astrid, Sit, Rene V., Chang, Stephen, Conley, Stephanie D., Mori, Yasuo, Seita, Jun, Berry, Gerald J., Shrager, Joseph B., Metzger, Ross J., Kuo, Christin S., Neff, Norma, Weissman, Irving L., Quake, Stephen R., Krasnow, Mark A.

“…Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles 1 – 9 , it has been difficult to systematically…”
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Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch by Ouadah, Youcef, Rojas, Enrique R., Riordan, Daniel P., Capostagno, Sarah, Kuo, Christin S., Krasnow, Mark A.

“…Pulmonary neuroendocrine (NE) cells are neurosensory cells sparsely distributed throughout the bronchial epithelium, many in innervated clusters of 20–30…”
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Axon-like protrusions promote small cell lung cancer migration and metastasis by Yang, Dian, Qu, Fangfei, Cai, Hongchen, Chuang, Chen-Hua, Lim, Jing Shan, Jahchan, Nadine, Grüner, Barbara M, S Kuo, Christin, Kong, Christina, Oudin, Madeleine J, Winslow, Monte M, Sage, Julien

“…Metastasis is the main cause of death in cancer patients but remains a poorly understood process. Small cell lung cancer (SCLC) is one of the most lethal and…”
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Neuroendocrinology of the lung revealed by single-cell RNA sequencing by Kuo, Christin S, Darmanis, Spyros, Diaz de Arce, Alex, Liu, Yin, Almanzar, Nicole, Wu, Timothy Ting-Hsuan, Quake, Stephen R, Krasnow, Mark A

“…Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that transmit airway status to the brain via sensory neurons and locally via calcitonin…”
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Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer by Cai, Ling, Liu, Hongyu, Huang, Fang, Fujimoto, Junya, Girard, Luc, Chen, Jun, Li, Yongwen, Zhang, Yu-An, Deb, Dhruba, Stastny, Victor, Pozo, Karine, Kuo, Christin S., Jia, Gaoxiang, Yang, Chendong, Zou, Wei, Alomar, Adeeb, Huffman, Kenneth, Papari-Zareei, Mahboubeh, Yang, Lin, Drapkin, Benjamin, Akbay, Esra A., Shames, David S., Wistuba, Ignacio I., Wang, Tao, Johnson, Jane E., Xiao, Guanghua, DeBerardinis, Ralph J., Minna, John D., Xie, Yang, Gazdar, Adi F.

“…Small cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but a subset of SCLC has been termed “variant” due to the loss of NE…”
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Interstitial macrophages are a focus of viral takeover and inflammation in COVID-19 initiation in human lung by Wu, Timothy Ting-Hsuan, Travaglini, Kyle J, Rustagi, Arjun, Xu, Duo, Zhang, Yue, Andronov, Leonid, Jang, SoRi, Gillich, Astrid, Dehghannasiri, Roozbeh, Martínez-Colón, Giovanny J, Beck, Aimee, Liu, Daniel Dan, Wilk, Aaron J, Morri, Maurizio, Trope, Winston L, Bierman, Rob, Weissman, Irving L, Shrager, Joseph B, Quake, Stephen R, Kuo, Christin S, Salzman, Julia, Moerner, W E, Kim, Peter S, Blish, Catherine A, Krasnow, Mark A

“…Early stages of deadly respiratory diseases including COVID-19 are challenging to elucidate in humans. Here, we define cellular tropism and transcriptomic…”
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Protein Interactions Regulating Vesicle Transport between the Endoplasmic Reticulum and Golgi Apparatus in Mammalian Cells by Hay, Jesse C, Chao, Daniel S, Kuo, Christin S, Scheller, Richard H

“…The proposed cis-Golgi vesicle receptor syntaxin 5 was found in a complex with Golgi-associated SNARE of 28 kDa (GOS-28), rbet1, rsly1, and two novel proteins…”
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Interstitial lung disease in children by Kuo, Christin S, Young, Lisa R

“…There has been tremendous progress in the approach to childhood interstitial lung diseases (chILD), with particular recognition that interstitial lung disease…”
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Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics by Kuo, Christin S, Desai, Tushar J

“…Childhood interstitial lung diseases (ILDs) are a diverse class of disorders affecting the alveolar gas exchange region that lack specific treatments and are…”
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Tissue-specific telomere shortening and degenerative changes in a patient with TINF2 mutation and dyskeratosis congenita by Roake, Caitlin M., Juntilla, Marisa, Agarwal-Hashmi, Rajni, Artandi, Steven, Kuo, Christin S.

“…•We present a case of dyskeratosis congenita (DC) caused by germline TINF2 mutation.•Autopsy samples reveal multisystem telomere shortening.•Pediatric bone…”
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Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs by Hay, Jesse C., Klumperman, Judith, Oorschot, Viola, Steegmaier, Martin, Kuo, Christin S., Scheller, Richard H.

“…ER-to-Golgi transport, and perhaps intraGolgi transport involves a set of interacting soluble N-ethylmaleimide-sensitive factor attachment protein receptor…”
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