Search Results - "Kunzelman, Karyn S"

Multivariable prediction of renal insufficiency developing after cardiac surgery by BROWN, Jeremiah R, COCHRAN, Richard P, WESTBROOK, Benjamin M, DUNTON, Robert F, MALENKA, David J, O'CONNOR, Gerald T, LEAVITT, Bruce J, DACEY, Lawrence J, ROSS, Cathy S, MACKENZIE, Todd A, KUNZELMAN, Karyn S, KRAMER, Robert S, HERNANDEZ, Felix, HELM, Robert E

“…Renal insufficiency after coronary artery bypass graft (CABG) surgery is associated with increased short-term and long-term mortality. We hypothesized that…”
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Long-Term Survival After Cardiac Surgery is Predicted by Estimated Glomerular Filtration Rate by Brown, Jeremiah R., PhD, Cochran, Richard P., MD, MacKenzie, Todd A., PhD, Furnary, Anthony P., MD, Kunzelman, Karyn S., PhD, Ross, Cathy S., MS, Langner, Craig W., MS, MBA, Charlesworth, David C., MD, Leavitt, Bruce J., MD, Dacey, Lawrence J., MD, Helm, Robert E., MD, Braxton, John H., MD, Clough, Robert A., MD, Dunton, Robert F., MD, O'Connor, Gerald T., PhD, DSc

“…Background Estimated glomerular filtration rate (eGFR) before coronary artery bypass graft (CABG) surgery is a key risk factor of in-hospital mortality…”
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Effect of Edge-to-Edge Mitral Valve Repair on Chordal Strain: Fluid-Structure Interaction Simulations by Toma, Milan, Einstein, Daniel R, Kohli, Keshav, Caroll, Sheridan L, Bloodworth, Charles H., IV, Cochran, Richard P, Kunzelman, Karyn S, Yoganathan, Ajit P

“…Edge-to-edge repair for mitral valve regurgitation is being increasingly performed in high-surgical risk patients using minimally invasive mitral clipping…”
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Perioperative increases in serum creatinine are predictive of increased 90-day mortality after coronary artery bypass graft surgery by BROWN, Jeremiah R, COCHRAN, Richard P, LEAVITT, Bruce J, MACKENZIE, Todd A, O'CONNOR, Gerald T, DACEY, Lawrence J, ROSS, Cathy S, KUNZELMAN, Karyn S, DUNTON, Robert F, BRAXTON, John H, CHARLESWORTH, David C, CLOUGH, Robert A, HELM, Robert E

“…Impaired renal function after coronary artery bypass graft (CABG) surgery is a key risk factor for in-hospital mortality. However, perioperative increases in…”
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Re-creation of sinuses is important for sparing the aortic valve: A finite element study by Grande-Allen, K.Jane, Cochran, Richard P., Reinhall, Per G., Kunzelman, Karyn S.

“…Objective: The treatment of choice for aortic valve insufficiency due to root dilatation has become root replacement with aortic valve sparing. However, root…”
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Fluid–Structure Interaction Analysis of Papillary Muscle Forces Using a Comprehensive Mitral Valve Model with 3D Chordal Structure by Toma, Milan, Jensen, Morten Ø., Einstein, Daniel R., Yoganathan, Ajit P., Cochran, Richard P., Kunzelman, Karyn S.

“…Numerical models of native heart valves are being used to study valve biomechanics to aid design and development of repair procedures and replacement devices…”
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Stress variations in the human aortic root and valve : The role of anatomic asymmetry by GRANDE, K. J, COCHRAN, R. P, REINHALL, P. G, KUNZELMAN, K. S

“…The asymmetry of the aortic valve and aortic root may influence their biomechanics, yet was not considered in previous valve models. This study developed an…”
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Fluid–structure interaction and structural analyses using a comprehensive mitral valve model with 3D chordal structure by Toma, Milan, Einstein, Daniel R., Bloodworth, Charles H., Cochran, Richard P., Yoganathan, Ajit P., Kunzelman, Karyn S.

“…Summary Over the years, three‐dimensional models of the mitral valve have generally been organized around a simplified anatomy. Leaflets have been typically…”
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Mechanisms of aortic valve incompetence: finite element modeling of aortic root dilatation by Grande, K.Jane, Cochran, Richard P, Reinhall, Per G, Kunzelman, Karyn S

“…Background. Idiopathic root dilatation often results in dysfunction of an otherwise normal aortic valve. To examine the effect of root dilatation on leaflet…”
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The relationship of normal and abnormal microstructural proliferation to the mitral valve closure sound by Einstein, Daniel R, Kunzelman, Karyn S, Reinhall, Per G, Nicosia, Mark A, Cochran, Richard P

“…Many diseases that affect the mitral valve are accompanied by the proliferation or degradation of tissue microstructure. The early acoustic detection of these…”
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Fluid-Structure Interaction Analysis of Ruptured Mitral Chordae Tendineae by Toma, Milan, Bloodworth, Charles H., Pierce, Eric L., Einstein, Daniel R., Cochran, Richard P., Yoganathan, Ajit P., Kunzelman, Karyn S.

“…The chordal structure is a part of mitral valve geometry that has been commonly neglected or simplified in computational modeling due to its complexity…”
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Aortic root and valve relationships: Impact on surgical repair by Kunzelman, Karyn S., Grande, K.Jane, David, Tirone E., Cochran, R.P., Verrier, Edward D.

“…A surgical procedure has recently been described for patients with aortic incompetence caused by annular dilation, but with normal aortic leaflets. The dilated…”
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High-resolution subject-specific mitral valve imaging and modeling: experimental and computational methods by Toma, Milan, Bloodworth, Charles H., Einstein, Daniel R., Pierce, Eric L., Cochran, Richard P., Yoganathan, Ajit P., Kunzelman, Karyn S.

“…The diversity of mitral valve (MV) geometries and multitude of surgical options for correction of MV diseases necessitates the use of computational modeling…”
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Special Mitral Valve Issue by Kunzelman, Karyn S.

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Fluid-structure interactions of the mitral valve and left heart: Comprehensive strategies, past, present and future by Einstein, Daniel R., Del Pin, Facundo, Jiao, Xiangmin, Kuprat, Andrew P., Carson, James P., Kunzelman, Karyn S., Cochran, Richard P., Guccione, Julius M., Ratcliffe, Mark B.

“…The remodeling that occurs after a posterolateral myocardial infarction can alter mitral valve function by creating conformational abnormalities in the mitral…”
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Quantitative Evaluation of Annuloplasty on Mitral Valve Chordae Tendineae Forces to Supplement Surgical Planning Model Development by Siefert, Andrew W., Rabbah, Jean-Pierre M., Pierce, Eric L., Kunzelman, Karyn S., Yoganathan, Ajit P.

“…Computational models of the heart’s mitral valve (MV) exhibit potential for preoperative surgical planning in ischemic mitral regurgitation (IMR). However…”
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Ambulatory intraaortic balloon pump use as bridge to heart transplant by Cochran, Richard P, Starkey, Thomas D, Panos, Anthony L, Kunzelman, Karyn S

“…Background. This study evaluates a modification of an ambulatory intraaortic balloon pump (IABP) technique used in patients with heart failure of ischemic…”
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A coupled fluid-structure finite element model of the aortic valve and root by Nicosia, Mark A, Cochran, Richard P, Einstein, Daniel R, Rutland, Christopher J, Kunzelman, Karyn S

“…The study aim was to develop a three-dimensional coupled fluid-structure finite element model of the aortic valve and root. This model extends previous purely…”
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Non-linear fluid-coupled computational model of the mitral valve by Einstein, Daniel R, Kunzelman, Karyn S, Reinhall, Per G, Nicosia, Mark A, Cochran, Richard P

“…The dynamics of the mitral valve result from the synergy of left heart geometry, local blood flow and tissue integrity. Herein is presented the first coupled…”
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Mechanisms of aortic valve incompetence: Finite-element modeling of Marfan syndrome by Grande-Allen, K.Jane, Cochran, Richard P., Reinhall, Per G., Kunzelman, Karyn S.

“…Objectives: Progressive aortic root dilatation and an increased aortic root elastic modulus have been documented in persons with Marfan syndrome. To examine…”
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