Search Results - "Kunze, Ruth"

Mutational Analysis of the Nsa2 N-Terminus Reveals Its Essential Role in Ribosomal 60S Subunit Assembly by Paternoga, Helge, Früh, Alexander, Kunze, Ruth, Bradatsch, Bettina, Baßler, Jochen, Hurt, Ed

“…The ribosome assembly factor Nsa2 is part of the Rea1-Rsa4-Nsa2 interconnected relay on nuclear pre-60S particles that is essential for 60S ribosome…”
Get full text

Correction: Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome by Sá-Moura, Bebiana, Kornprobst, Markus, Kharde, Satyavati, Ahmed, Yasar Luqman, Stier, Gunter, Kunze, Ruth, Sinning, Irmgard, Hurt, Ed

“…[This corrects the article DOI: 10.1371/journal.pone.0183272.]…”
Get full text

Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome by Sá-Moura, Bebiana, Kornprobst, Markus, Kharde, Satyavati, Ahmed, Yasar Luqman, Stier, Gunter, Kunze, Ruth, Sinning, Irmgard, Hurt, Ed

“…In eukaryotes, ribosome assembly is a highly complex process that involves more than 200 assembly factors that ensure the folding, modification and processing…”
Get full text

Probing the nucleoporin FG repeat network defines structural and functional features of the nuclear pore complex by Stelter, Philipp, Kunze, Ruth, Fischer, Jessica, Hurt, Ed

“…Unraveling the organization of the FG repeat meshwork that forms the active transport channel of the nuclear pore complex (NPC) is key to understanding the…”
Get full text

Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins by Lutzmann, Malik, Kunze, Ruth, Buerer, Andrea, Aebi, Ueli, Hurt, Ed

“…Now that it is likely that all yeast nucleoporins are known, one of the ultimate goals is the in vitro assembly of the entire nuclear pore complex from its ∼30…”
Get full text

Reconstitution of Nup157 and Nup145N into the Nup84 Complex[boxs] by Lutzmann, Malik, Kunze, Ruth, Stangl, Karin, Stelter, Philipp, Tóth, Katalin Fejes, Böttcher, Bettina, Hurt, Ed

“…About 30 different nucleoporins (Nups) constitute the nuclear pore complex. We have affinity-purified 28 of these nuclear pore proteins and identified new…”
Get full text

Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel by Fischer, Jessica, Teimer, Roman, Amlacher, Stefan, Kunze, Ruth, Hurt, Ed

“…An in vitro –reconstitution approach reveals the interactions between nuclear pore complex modules. Short motifs within linker nucleoporins connect the…”
Get full text

The Efg1–Bud22 dimer associates with the U14 snoRNP contacting the 5′ rRNA domain of an early 90S pre-ribosomal particle by Beine-Golovchuk, Olga, Kallas, Martina, Kunze, Ruth, Griesel, Sabine, Baßler, Jochen

“…Abstract The DEAD-box helicase Dbp4 plays an essential role during the early assembly of the 40S ribosome, which is only poorly understood to date. By applying…”
Get full text

Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration by Cheng, Jingdong, Baßler, Jochen, Fischer, Paulina, Lau, Benjamin, Kellner, Nikola, Kunze, Ruth, Griesel, Sabine, Kallas, Martina, Berninghausen, Otto, Strauss, Daniela, Beckmann, Roland, Hurt, Ed

“…Eukaryotic ribosome biogenesis involves RNA folding and processing that depend on assembly factors and small nucleolar RNAs (snoRNAs). The 90S (SSU-processome)…”
Get full text

Insight into Structure and Assembly of the Nuclear Pore Complex by Utilizing the Genome of a Eukaryotic Thermophile by Amlacher, Stefan, Sarges, Phillip, Flemming, Dirk, van Noort, Vera, Kunze, Ruth, Devos, Damien P., Arumugam, Manimozhiyan, Bork, Peer, Hurt, Ed

“…Despite decades of research, the structure and assembly of the nuclear pore complex (NPC), which is composed of ∼30 nucleoporins (Nups), remain elusive. Here,…”
Get full text

Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension by Stelter, Philipp, Huber, Ferdinand M., Kunze, Ruth, Flemming, Dirk, Hoelz, André, Hurt, Ed

“…Eukaryotic ribosome biogenesis requires nuclear import and hierarchical incorporation of ∼80 ribosomal proteins (RPs) into the ribosomal RNA core. In contrast…”
Get full text

Structural Basis of the Nic96 Subcomplex Organization in the Nuclear Pore Channel by Schrader, Nils, Stelter, Philipp, Flemming, Dirk, Kunze, Ruth, Hurt, Ed, Vetter, Ingrid R.

“…Nic96 is a conserved nucleoporin that recruits the Nsp1-Nup49-Nup57 complex, a module with Phe-Gly (FG) repeats, to the central transport channel of the…”
Get full text

Monitoring Spatiotemporal Biogenesis of Macromolecular Assemblies by Pulse-Chase Epitope Labeling by Stelter, Philipp, Kunze, Ruth, Radwan, Monika, Thomson, Emma, Thierbach, Karsten, Thoms, Matthias, Hurt, Ed

“…Many cellular proteins perform their roles within macromolecular assemblies. Hence, an understanding of how these multiprotein complexes form is a fundamental…”
Get full text

Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension by Stelter, Philipp, Huber, Ferdinand M., Kunze, Ruth, Flemming, Dirk, Hoelz, André, Hurt, Ed

Get full text

Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex by Höpfner, Dominic, Stelter, Philipp, Kunze, Ruth, Diepholz, Meikel, Philippsen, Peter, Hurt, Ed, Flemming, Dirk, Böttcher, Bettina

“…Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. Here, we discovered an unexpected role for yeast…”
Get full text