Search Results - "Kunze, Diana L."

Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP by Schilling, William P, McGrath, Morgan K, Yang, Tianen, Glazebrook, Patricia A, Faingold, Carl L, Kunze, Diana L

“…This study was designed to evaluate cardiac and respiratory dysfunction in a mouse model of sudden unexpected death in epilepsy i.e., SUDEP. We simultaneously…”
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KCNQ/M-currents contribute to the resting membrane potential in rat visceral sensory neurons by Wladyka, Cynthia L., Kunze, Diana L.

“…The M-current is a slowly activating, non-inactivating potassium current that has been shown to be present in numerous cell types. In this study, KCNQ2, Q3 and…”
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Endogenous brain-derived neurotrophic factor in the nucleus tractus solitarius tonically regulates synaptic and autonomic function by Clark, Catharine G, Hasser, Eileen M, Kunze, Diana L, Katz, David M, Kline, David D

“…Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are highly expressed in the nucleus tractus solitarius (nTS), the principal target of…”
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An afferent explanation for sexual dimorphism in the aortic baroreflex of rat by Santa Cruz Chavez, Grace C, Li, Bai-Yan, Glazebrook, Patricia A, Kunze, Diana L, Schild, John H

“…Sex differences in baroreflex (BRx) function are well documented. Hormones likely contribute to this dimorphism, but many functional aspects remain unresolved…”
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Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors by Tatalovic, Milos, Glazebrook, Patricia A., Kunze, Diana L.

“…► We evaluated the presence of P/Q type calcium channel in nodose sensory neurons. ► The P/Q-type channel supplies the major calcium current in subset of large…”
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The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats by Wladyka, Cynthia L., Feng, Bin, Glazebrook, Patricia A., Schild, John H., Kunze, Diana L.

“…The ion channels responsible for the pattern and frequency of discharge in arterial baroreceptor terminals are, with few exceptions, unknown. In this study we…”
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Differential Distribution and Function of Hyperpolarization-Activated Channels in Sensory Neurons and Mechanosensitive Fibers by Doan, Thanh N, Stephans, Kevin, Ramirez, Angelina N, Glazebrook, Patricia A, Andresen, Michael C, Kunze, Diana L

“…Sensory neurons express hyperpolarization-activated currents (I(H)) that differ in magnitude and kinetics within the populations. We investigated the…”
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Potassium channels Kv1.1, Kv1.2 and Kv1.6 influence excitability of rat visceral sensory neurons by Glazebrook, Patricia A., Ramirez, Angelina N., Schild, John H., Shieh, Char‐Chang, Doan, Thanh, Wible, Barbara A., Kunze, Diana L.

“…Voltage-gated potassium channels, Kv1.1, Kv1.2 and Kv1.6, were identified as PCR products from mRNA prepared from nodose ganglia. Immunocytochemical studies…”
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Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice by Kline, David D, Ogier, Michael, Kunze, Diana L, Katz, David M

“…Postnatal deficits in brain-derived neurotrophic factor (BDNF) are thought to contribute to pathogenesis of Rett syndrome (RTT), a progressive…”
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Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body by Buniel, Maria, Glazebrook, Patricia A., Ramirez-Navarro, Angelina, Kunze, Diana L.

“…The chemosensory glomus cells of the carotid body (CB) detect changes in O2 tension. Carotid sinus nerve fibers, which originate from peripheral sensory…”
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Dopamine Modulates Synaptic Transmission in the Nucleus of the Solitary Tract by Kline, David D, Takacs, Kristin N, Ficker, Eckhard, Kunze, Diana L

“…  1 Rammelkamp Center for Education and Research, MetroHealth Medical System and   2 Department of Neuroscience, Case Western Reserve University, Cleveland,…”
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Kv2 channels contribute to neuronal activity within the vagal afferent-nTS reflex arc by Ramirez-Navarro, Angelina, Lima-Silveira, Ludmila, Glazebrook, Patricia A, Dantzler, Heather A, Kline, David D, Kunze, Diana L

“…Diversity in the functional expression of ion channels contributes to the unique patterns of activity generated in visceral sensory A-type myelinated neurons…”
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TRPV1 channels contribute to spontaneous glutamate release in nucleus tractus solitarii following chronic intermittent hypoxia by Kline, David D, Wang, Sheng, Kunze, Diana L

“…Chronic intermittent hypoxia (CIH) reduces afferent-evoked excitatory postsynaptic currents (EPSCs) but enhances basal spontaneous (s) and asynchronous (a)…”
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P2X purinergic receptor channel expression and function in bovine aortic endothelium by Ramirez, Angelina N, Kunze, Diana L

“…We examined bovine aortic endothelial cells (BAECs) for the functional expression of P2X receptors, the ATP-gated cation channels. We identified the P2X…”
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The Kv1.1 null mouse, a model of sudden unexpected death in epilepsy (SUDEP) by Moore, Brian M., Jerry Jou, Chuanchau, Tatalovic, Milos, Kaufman, Elizabeth S., Kline, David D., Kunze, Diana L.

“…Summary Objective Kv1.1 potassium channel null mouse (NULL) exhibits spontaneous seizure‐related bradycardia, dies following seizure, and has been proposed as…”
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Adaptive Depression in Synaptic Transmission in the Nucleus of the Solitary Tract after In Vivo Chronic Intermittent Hypoxia: Evidence for Homeostatic Plasticity by Kline, David D, Ramirez-Navarro, Angelina, Kunze, Diana L

“…The respiratory system is highly pliable in its adaptation to low-oxygen (hypoxic) environments. After chronic intermittent hypoxia (CIH), alterations in the…”
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Brain-Derived Neurotrophic Factor Acutely Inhibits AMPA-Mediated Currents in Developing Sensory Relay Neurons by Balkowiec, Agnieszka, Kunze, Diana L, Katz, David M

“…Brain-derived neurotrophic factor (BDNF) is expressed by many primary sensory neurons that no longer require neurotrophins for survival, indicating that BDNF…”
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Differential distribution of voltage-gated channels in myelinated and unmyelinated baroreceptor afferents by Schild, John H, Kunze, Diana L

“…Abstract Voltage gated ion channels (VGC) make possible the frequency coding of arterial pressure and the neurotransmission of this information along…”
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KCa1.1 channel contributes to cell excitability in unmyelinated but not myelinated rat vagal afferents by Li, Bai-Yan, Glazebrook, Patricia, Kunze, Diana L, Schild, John H

“…High conductance calcium-activated potassium (BK(Ca)) channels can modulate cell excitability and neurotransmitter release at synaptic and afferent terminals…”
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Dopamine Inhibits N-Type Channels in Visceral Afferents to Reduce Synaptic Transmitter Release Under Normoxic and Chronic Intermittent Hypoxic Conditions by Kline, David D, Hendricks, Gabriel, Hermann, Gerlinda, Rogers, Richard C, Kunze, Diana L

“…1 Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio; 2 Rammelkamp Center for Education and Research, MetroHealth Medical System,…”
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