Search Results - "Kunz, Kevin A"

Thermolysis of Geminal Diazido Malonamides: Simple Access to Tetrazoles and Functionalization of In Situ Formed Isocyanates by Bensberg, Kathrin, Kunz, Kevin A., Kirsch, Stefan F.

“…In recent years, the development of synthetic methods to afford nitrogen‐containing heterocycles has become increasingly popular. Among these, tetrazoles – an…”
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Synthesis of N 2‑Substituted 1,2,3-Triazoles by Kunz, Kevin A., Springer, Bastian L., Klahn, Philipp, Aldemir, Hülya, Mohr, Fabian, Kirsch, Stefan F.

“…We present a novel synthetic approach for the synthesis of the 1,2,3-triazole core, with a particular focus on the direct and regioselective synthesis of the…”
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Synthesis of N2-Substituted 1,2,3-Triazoles by Kunz, Kevin A, Springer, Bastian L, Klahn, Philipp, Aldemir, Hülya, Mohr, Fabian, Kirsch, Stefan F

“…We present a novel synthetic approach for the synthesis of the 1,2,3-triazole core, with a particular focus on the direct and regioselective synthesis of the…”
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Thermolysis of Geminal Diazides: Reagent-Free Synthesis of 3‑Hydroxypyridines by Erhardt, Hellmuth, Kunz, Kevin A, Kirsch, Stefan F

“…An operationally simple protocol for the rapid and efficient construction of highly substituted 3-hydroxypyridines is presented. The thermally induced…”
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Malaria Box-Inspired Discovery of N‑Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials by Mathew, Jopaul, Ding, Sha, Kunz, Kevin A, Stacy, Emily E, Butler, Joshua H, Haney, Reagan S, Merino, Emilio F, Butschek, Grant J, Rizopoulos, Zaira, Totrov, Maxim, Cassera, Maria B, Carlier, Paul R

“…Virtual ligand screening of a publicly available database of antimalarial hits using a pharmacophore derived from antimalarial MMV008138 identified…”
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β‑Carboline-3-carboxamide Antimalarials: Structure–Activity Relationship, ADME-Tox Studies, and Resistance Profiling by Mathew, Jopaul, Zhou, Bo, Haney, Reagan S., Kunz, Kevin A., Do Amaral, Leticia S., Roy Chowdhury, Rudraneel, Butler, Joshua H., Li, Haibo, Chakraborty, Amarraj J., Tabassum, Anika, Bremers, Emily K., Merino, Emilio F., Coyle, Rachael, Lee, Marcus C. S., Baud, Delphine, Brand, Stephen, Totrov, Maxim, Cassera, Maria Belen, Carlier, Paul R.

“…The development of parasite resistance to both artemisinin derivatives and their partner drugs jeopardizes the effectiveness of the artemisinin combination…”
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