Search Results - "Kuntz, A."
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The microstructure and micromechanics of the tendon–bone insertion
Published in Nature materials (01-06-2017)“…The exceptional mechanical properties of the load-bearing connection of tendon to bone rely on an intricate interplay of its biomolecular composition,…”
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Psychopathological characteristics of patients eligible for a diacethylmorphine prescription program: an ecological pilot study
Published in European psychiatry (01-06-2022)“…IntroductionAgonist opiate treatments with diacethylmorphin (DAM) for heroin addiction have proven their effectiveness for a long time. But few studies focused…”
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Safety evaluation of lotilaner in dogs after oral administration as flavoured chewable tablets (Credelio™)
Published in Parasites & vectors (01-11-2017)“…Lotilaner (Credelio™, Elanco) is a novel isoxazoline that provides rapid speed of flea and tick knockdown which is sustained for at least 1 month following…”
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Efficient decellularization for tissue engineering of the tendon-bone interface with preservation of biomechanics
Published in PloS one (07-02-2017)“…Interfaces between tendon/ligament and bone ("entheses") are highly specialized tissues that allow for stress transfer between mechanically dissimilar…”
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Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II
Published in European journal of cell biology (01-06-2024)“…The RAS isoforms (KRAS, HRAS and NRAS) have distinct cancer type-specific profiles. NRAS mutations are the second most prevalent RAS mutations in skin and…”
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Safety of lotilaner flavoured chewable tablets (Credelio TM ) after oral administration in cats
Published in Parasites & vectors (13-07-2018)“…Lotilaner is a new member of the isoxazoline class for treatment of flea and tick infestations in cats. This laboratory study with lotilaner vanilla-yeast…”
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Biomarkers for tissue engineering of the tendon-bone interface
Published in PloS one (03-01-2018)“…The tendon-bone interface (enthesis) is a highly sophisticated biomaterial junction that allows stress transfer between mechanically dissimilar materials. The…”
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Golgi α-mannosidase II cleaves two sugars sequentially in the same catalytic site
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-2008)“…Golgi α-mannosidase II (GMII) is a key glycosyl hydrolase in the N-linked glycosylation pathway. It catalyzes the removal of two different mannosyl linkages of…”
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Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
Published in Leukemia (01-03-2009)Get full text
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Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats
Published in Pharmaceutics (24-02-2024)“…Kratom and cannabidiol products are used to self-treat a variety of conditions, including anxiety and pain, and to elevate mood. Research into the individual…”
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Farmers’ Perceptions of Agricultural Land Abandonment in Rural Western New York State
Published in Land (Basel) (01-12-2018)“…Over the last century, the U.S. economy has favored large-scale agribusiness over small-scale farming. In some regions, this trend has led to the abandonment…”
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419 A CTS team approach to identifying thematic constructs related to kratom use during pregnancy and breastfeeding: A qualitative analysis of social media posts
Published in Journal of clinical and translational science (01-04-2023)“…OBJECTIVES/GOALS: Research on the safety of perinatal kratom use - an herb that acts on opioid receptors - is scarce. Our transdisciplinary clinical and…”
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Apocrine gland anal sac adenocarcinoma in cats: 30 cases (1994-2015)
Published in Journal of the American Veterinary Medical Association (15-03-2019)“…OBJECTIVE To describe the signalment, clinical signs, biological behavior, and outcome for cats with apocrine gland anal sac adenocarcinoma (AGASACA) that…”
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Recycled products are not always skin-friendly: Occupational dermatitis due to recycled plastic
Published in Annales de dermatologie et de vénéréologie (01-09-2021)Get full text
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Random mutagenesis reveals residues of JAK2 critical in evading inhibition by a tyrosine kinase inhibitor
Published in PloS one (16-08-2012)“…The non-receptor tyrosine kinase JAK2 is implicated in a group of myeloproliferative neoplasms including polycythemia vera, essential thrombocythemia, and…”
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Synthesis and Biological Evaluation of Heteroanalogues of Kotalanol and De-O-Sulfonated Kotalanol
Published in Organic letters (05-03-2010)“…The synthesis of nitrogen and selenium analogues of kotalanol and de-O-sulfonated kotalanol, naturally occurring sulfonium-ion glucosidase inhibitors isolated…”
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Magma Evolution and Ascent at the Craters of the Moon and Neighboring Volcanic Fields, Southern Idaho, USA: Implications for the Evolution of Polygenetic and Monogenetic Volcanic Fields
Published in Journal of petrology (01-09-2009)“…The evolution of polygenetic and monogenetic volcanic fields must reflect differences in magma processing during ascent. To assess their evolution we use…”
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Structure of Golgi α-mannosidase II: a target for inhibition of growth and metastasis of cancer cells
Published in The EMBO journal (15-06-2001)“…Golgi α‐mannosidase II, a key enzyme in N‐glycan processing, is a target in the development of anti‐ cancer therapies. The crystal structure of Drosophila…”
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Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity
Published in Nature communications (23-11-2024)“…Proteolysis-targeting chimeras (PROTACs) have been explored for the degradation of drug targets for more than two decades. However, only a handful of E3 ligase…”
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