Search Results - "Kuntsche, Judith"

Tumor Accumulation of NIR Fluorescent PEG–PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model by Schädlich, Andreas, Caysa, Henrike, Mueller, Thomas, Tenambergen, Frederike, Rose, Cornelia, Göpferich, Achim, Kuntsche, Judith, Mäder, Karsten

“…Cancer therapies are often terminated due to serious side effects of the drugs. The cause is the nonspecific distribution of chemotherapeutic agents to both…”
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Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug by Tretiakova, Daria, Le-Deigen, Irina, Onishchenko, Natalia, Kuntsche, Judith, Kudryashova, Elena, Vodovozova, Elena

“…Previously, a liposomal formulation of a chemotherapeutic agent melphalan (Mlph) incorporated in a fluid lipid bilayer of natural phospholipids in the form of…”
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Bone Morphogenetic Protein 2 (BMP-2) Aggregates Can be Solubilized by Albumin-Investigation of BMP-2 Aggregation by Light Scattering and Electrophoresis by Sundermann, Julius, Zagst, Holger, Kuntsche, Judith, Wätzig, Hermann, Bunjes, Heike

“…Bone morphogenetic protein 2 (BMP-2) has a high tendency to aggregate at physiological pH and physiological ionic strength, which can complicate the…”
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Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres by Weiss, Verena M., Naolou, Toufik, Hause, Gerd, Kuntsche, Judith, Kressler, Jörg, Mäder, Karsten

“…Poly(glycerol adipate) (PGA) is a biodegradable polymer with promising features for nanoparticulate drug carrier systems. By acylation of PGA with fatty acids,…”
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Feasibility of the preparation of cochleate suspensions from naturally derived phosphatidylserines by Kristensen, Søren, Hassan, Khadeija, Andersen, Nadia Skarnager, Steiniger, Frank, Kuntsche, Judith

“…Introduction Cochleates are cylindrical particles composed of dehydrated phospholipid bilayers. They are typically prepared by addition of calcium ions to…”
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In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis by Göttel, Benedikt, Lucas, Henrike, Syrowatka, Frank, Knolle, Wolfgang, Kuntsche, Judith, Heinzelmann, Joana, Viestenz, Arne, Mäder, Karsten

“…The purpose of our research was the development of Amphotericin B-loaded gelling nanofibers for the treatment of keratomycosis. Different formulation…”
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Molecular Networks and Macromolecular Molar Mass Distributions for Preliminary Characterization of Danish Craft Beers by Nielsen, Marcus M. K., Hughes, Sean Sebastian, Kuntsche, Judith, Malmendal, Anders, Jenssen, Håvard, Nielsen, Carsten Uhd, Prabhala, Bala Krishna

“…Beer is one of the most widely consumed beverages containing up to 200,000 unique small molecules and a largely uncharacterized macromolecular and particulate…”
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Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles by Dutz, Silvio, Kuntsche, Judith, Eberbeck, Dietmar, Müller, Robert, Zeisberger, Matthias

“…Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this…”
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Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems by Kuntsche, Judith, Horst, Jennifer C., Bunjes, Heike

“…Cryogenic transmission electron microscopy (cryo-TEM) has evolved into an indispensable tool for the characterization of colloidal drug delivery systems. It…”
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Drastic differences between the release kinetics of two highly related porphyrins in liposomal membranes: mTHPP and pTHPP by Kuntsche, Judith, Rajakulendran, Kirishana, Sabriye, Hibo Mohamed Takane, Tawakal, Navidullah, Khandelia, Himanshu, Hakami Zanjani, Ali Asghar

“…[Display omitted] •Minor structural differences of hydrophobic porphyrins can distinctly influence their release properties from liposomes.•mTHPP (meta OH)…”
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Editorial to the special EJPS issue “(Trans)dermal drug delivery: Emerging trends to study and overcome the skin barrier” by Bouwstra, Joke

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The use of asymmetrical flow field-flow fractionation with on-line detection in the study of drug retention within liposomal nanocarriers and drug transfer kinetics by Hinna, Askell Hvid, Hupfeld, Stefan, Kuntsche, Judith, Brandl, Martin

“…[Display omitted] •A substantially improved in vitro tool is described for prediction of the retention of a lipophilic model drug within liposomal carriers.•It…”
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Analysis of liposomes using asymmetrical flow field-flow fractionation: Separation conditions and drug/lipid recovery by Kuntsche, Judith, Decker, Christiane, Fahr, Alfred

“…Liposomes composed of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol were analyzed by asymmetrical flow field‐flow fractionation coupled…”
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The ROC skin model: A robust skin equivalent for permeation and live cell imaging studies by Jakobsen, Nicoline Dorothea, Kaiser, Katharina, Ebbesen, Morten Frendø, Lauritsen, Line, Gjerstorff, Morten Frier, Kuntsche, Judith, Brewer, Jonathan R.

“…Rat epidermal keratinocyte (REK) Organotypic culture (ROC) is an epidermis model that is robust and inexpensive to develop and maintain, and it has in previous…”
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Temoporfin-loaded liposomes: Physicochemical characterization by Kuntsche, Judith, Freisleben, Ines, Steiniger, Frank, Fahr, Alfred

“…Temoporfin (mTHPC) is a potent but highly hydrophobic second-generation photosensitizer and has been approved for the palliative treatment of patients with…”
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Asymmetrical flow field-flow fractionation with on-line detection for drug transfer studies: a feasibility study by Hinna, Askell, Steiniger, Frank, Hupfeld, Stefan, Brandl, Martin, Kuntsche, Judith

“…Knowledge about drug retention within colloidal carriers is of uppermost importance particularly if drug targeting is anticipated. The aim of the present study…”
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β-Cyclodextrin-dextran polymers for the solubilization of poorly soluble drugs by di Cagno, Massimiliano, Terndrup Nielsen, Thorbjørn, Lambertsen Larsen, Kim, Kuntsche, Judith, Bauer-Brandl, Annette

“…[Display omitted] The aim of this study was to assess the potential of novel β-cyclodextrin (βCD)-dextran polymers for drug delivery. The size distribution of…”
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Filter-extruded liposomes revisited: a study into size distributions and morphologies in relation to lipid-composition and process parameters by Hinna, Askell, Steiniger, Frank, Hupfeld, Stefan, Stein, Paul, Kuntsche, Judith, Brandl, Martin

“…Filter-extrusion is a widely used technique for down-sizing of phospholipid vesicles. In order to gain a detailed insight into size and size distributions of…”
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Selective partitioning of cholesterol and a model drug into liposomes of varying size by Decker, Christiane, Fahr, Alfred, Kuntsche, Judith, May, Sylvio

“…► We measured the size-selective partitioning of two solutes into liposomes. ► In small unilamellar liposomes the solute-to-lipid ratio is a function of size…”
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Mechanism and kinetics of the loss of poorly soluble drugs from liposomal carriers studied by a novel flow field-flow fractionation-based drug release−/transfer-assay by Hinna, Askell Hvid, Hupfeld, Stefan, Kuntsche, Judith, Bauer-Brandl, Annette, Brandl, Martin

“…Liposomes represent a versatile drug formulation approach e.g. for improving the water-solubility of poorly soluble drugs but also to achieve drug targeting…”
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