Search Results - "Kuntner, C."

Pgp-Mediated Interaction Between (R)-[11C]Verapamil and Tariquidar at the Human Blood-Brain Barrier: A Comparison With Rat Data by Bauer, M, Zeitlinger, M, Karch, R, Matzneller, P, Stanek, J, Jäger, W, Böhmdorfer, M, Wadsak, W, Mitterhauser, M, Bankstahl, J P, Löscher, W, Koepp, M, Kuntner, C, Müller, M, Langer, Oliver

“…Using positron emission tomography (PET) imaging we assessed, in vivo, the interaction between a microdose of (R)‐[11C]verapamil (a P‐glycoprotein (Pgp)…”
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A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier by Bankstahl, Jens P, Bankstahl, Marion, Kuntner, Claudia, Stanek, Johann, Wanek, Thomas, Meier, Martin, Ding, Xiao-Qi, Müller, Markus, Langer, Oliver, Löscher, Wolfgang

“…Approximately one-third of epilepsy patients are pharmacoresistant. Overexpression of P-glycoprotein and other multidrug transporters at the blood-brain…”
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SP-0515: Multi-modal preclinical imaging: challenges and opportunities in cancer discovery and treatment by Kuntner, C, Wanek, T, Langer, O

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FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo by Cejka, D, Kuntner, C, Preusser, M, Fritzer-Szekeres, M, Fueger, B J, Strommer, S, Werzowa, J, Fuereder, T, Wanek, T, Zsebedics, M, Mueller, M, Langer, O, Wacheck, V

“…This study aimed to test whether [ 18 F]fluoro- D -glucose (FDG) uptake of tumours measured by positron emission tomography (PET) can be used as surrogate…”
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Validation of PET-SORTEO Monte Carlo simulations for the geometries of the MicroPET R4 and Focus 220 PET scanners by Lartizien, C, Kuntner, C, Goertzen, A L, Evans, A C, Reilhac, A

“…PET-SORTEO is a Monte Carlo-based simulator that enables the fast generation of realistic PET data for the geometry of the ECAT EXACT HR+ scanner. In order to…”
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The ClearPET™ project: development of a 2nd generation high-performance small animal PET scanner by Ziemons, K., E. Auffray, Barbier, R., Brandenburg, G., Bruyndonckx, P., Choi, Y., Christ, D., Costes, N., Declais, Y., Devroede, O., Dujardin, C., Fedorovd, A., Heinrichs, U., Korjik, M., Krieguer, M., Kuntner, C., Largeron, G., Lartizien, C., Larue, H., Lecoq, P., Leonard, S., Marteau, J., Morel, Ch, Mosset, J.B., Parl, Ch, Pedrini, Ch, Petrosyan, A.G., Pietrzyk, U., Rey, M., Saladino, S., Sappey-Marinier, D., Simon, L., Streun, M., Tavernier, S., Vieira, J.M.

“…Second generation high-performance PET scanners, called ClearPET™11ClearPET is a trademark of the Crystal Clear Collaboration., have been developed by working…”
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Amyloid PET and MRI in Alzheimer's disease and mild cognitive impairment by Dimou, E, Booij, J, Rodrigues, M, Prosch, H, Attems, J, Knoll, P, Zajicek, B, Dudczak, R, Mostbeck, G, Kuntner, C, Langer, O, Bruecke, T, Mirzaei, S

“…The neurodegenerative disorder Alzheimer's disease (AD) is the most common form of dementia. It is characterized by progressive impairment of cognitive…”
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Intrinsic energy resolution and light output of the Lu0.7Y0.3AP:Ce scintillator by Kuntner, C, Auffray, E, Lecoq, P, Pizzolotto, C, Schneegans, M

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18F, 11C and 68Ga in small animal PET imaging. Evaluation of partial volume correction methods by Muellauer, J, Willimayer, R, Goertzen, A L, Wanek, T, Langer, O, Birkfellner, W, Kuntner, C

“…The partial volume effect (PVE) significantly affects quantitative accuracy in PET. In this study we used a micro-hollow sphere phantom filled with 18F, 11C or…”
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FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo by CEJKA, D, KUNTNER, C, MUELLER, M, LANGER, O, WACHECK, V, PREUSSER, M, FRITZER-SZEKERES, M, FUEGER, B. J, STROMMER, S, WERZOWA, J, FUEREDER, T, WANEK, T, ZSEBEDICS, M

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Development of an optimized LSO/LuYAP phoswich detector head for the Lausanne ClearPET demonstrator by Mosset, J.-B., Devroede, O., Krieguer, M., Rey, M., Vieira, J.-M., Jung, J.H., Kuntner, C., Streun, M., Ziemons, K., Auffray, E., Sempere-Roldan, P., Lecoq, P., Bruyndonckx, P., Loude, J.-F., Tavernier, S., Morel, C.

“…This paper describes the LSO/LuYAP phoswich detector head developed for the ClearPET small animal PET scanner demonstrator that is under construction in…”
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Advances in the scintillation performance of LuYAP:Ce single crystals by Kuntner, C., Auffray, E., Bellotto, D., Dujardin, C., Grumbach, N., Kamenskikh, I.A., Lecoq, P., Mojzisova, H., Pedrini, C., Schneegans, M.

“…In the last years, there has been an effort to study and improve the performance of cerium doped Lu0.7Y0.3AlO3 crystals. Since the first grown boules produced…”
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The ClearPET project by Auffray, E, Bruyndonckx, P, Devroede, O, Fedorov, A, Heinrichs, U, Korjik, M, Krieguer, M, Kuntner, C, Lartizien, C, Lecoq, P, Leonard, S, Morel, Ch, Mosset, J.B, Pedrini, Ch, Petrosian, A, Pietrzyk, U, Rey, M, Saladino, S, Sappey-Marinier, D, Simon, L, Streun, M, Tavernier, S, Vieira, J.M, Ziemons, K

“…The Crystal Clear Collaboration has designed and is building a high-resolution small animal PET scanner. The design is based on the use of the Hamamatsu…”
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Scintillation properties and mechanism in Lu0.8Y0.2AlO3:Ce by Kuntner, C, Aiginger, H, Auffray, E, Glodo, J, Kapusta, M, Lecoq, P, Moszynski, M, Schneegans, M, Szupryczynski, P, Wojtowicz, A.J

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Scintillation properties of mixed LuYAP crystals in view of their use in a small animal PET scanner in phoswich configuration by Kuntner, C., Auffray, E., Dujardin, C., Lecoq, P., Pedrini, C., Schneegans, M.

“…Phoswich detectors are currently being considered by a number of investigators for depth-of-interaction (DOI) measurements in PET. In this work, the…”
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( R )-[11 C]verapamil is selectively transported by murine and human P-glycoprotein at the blood–brain barrier, and not by MRP1 and BCRP by Römermann, Kerstin, Wanek, Thomas, Bankstahl, Marion, Bankstahl, Jens P, Fedrowitz, Maren, Müller, Markus, Löscher, Wolfgang, Kuntner, Claudia, Langer, Oliver

“…Abstract Introduction Positron emission tomography (PET) with [11 C]verapamil, either in racemic form or in form of the ( R )-enantiomer, has been used to…”
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Development of an optimised LSO/LuYAP phoswich detector head for the ClearPET camera by Mosset, J.-B., Devroede, O., Krieguer, M., Rey, M., Vieira, J.-M., Jung, J.H., Kuntner, C., Streun, M., Ziemons, K., Auffray, E., Sempere-Roldan, P., Lecoq, P., Bruyndonckx, P., Loude, J.-F., Tavernier, S., Morel, C.

“…The paper describes the LSO/LuYAP phoswich detector head developed for the ClearPET small animal PET scanner demonstrator that is under construction within the…”
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Optical and scintillation characteristics of Bridgman LuAP single crystals for positron emission tomography by Petrosyan, A.G., Derdzyan, M.V., Lecoq, P., Auffray, E., Pedrini, C., Dujardin, C., Kuntner, C., Sempere, P., Ovanesyan, K.L., Kamenskikh, I.A.

“…An efficient growth process is developed employing the vertical Bridgman method, which provides for LuAP single crystals of high optical quality and optimized…”
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Assessment of cerebral P-glycoprotein expression and function with PET by combined [11 C]inhibitor and [11 C]substrate scans in rats by Müllauer, Julia, Karch, Rudolf, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Mairinger, Severin, Müller, Markus, Löscher, Wolfgang, Langer, Oliver, Kuntner, Claudia

“…Abstract Introduction The adenosine triphosphate-binding cassette (ABC) transporter P-glycoprotein (Pgp) protects the brain from accumulation of lipophilic…”
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Intrinsic energy resolution and light output of the Lu 0.7Y 0.3AP:Ce scintillator by Kuntner, C, Auffray, E, Lecoq, P, Pizzolotto, C, Schneegans, M

“…Light output and energy resolution for a 2×2×10 mm 3 LuYAP:Ce crystal coupled to a XP2020Q photomultiplier were studied. The measured light output of 8530…”
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