Search Results - "Kunning, Sheryl R"

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma by Ruffin, Ayana T., Cillo, Anthony R., Tabib, Tracy, Liu, Angen, Onkar, Sayali, Kunning, Sheryl R., Lampenfeld, Caleb, Atiya, Huda I., Abecassis, Irina, Kürten, Cornelius H. L., Qi, Zengbiao, Soose, Ryan, Duvvuri, Umamaheswar, Kim, Seungwon, Oesterrich, Steffi, Lafyatis, Robert, Coffman, Lan G., Ferris, Robert L., Vignali, Dario A. A., Bruno, Tullia C.

“…Current immunotherapy paradigms aim to reinvigorate CD8 + T cells, but the contribution of humoral immunity to antitumor immunity remains understudied. Here,…”
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Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes by Karapetyan, Lilit, AbuShukair, Hassan M, Li, Aofei, Knight, Andrew, Al Bzour, Ayah Nedal, MacFawn, Ian P, Thompson, Zachary J, Chen, Ann, Yang, Xi, Dadey, Rebekah, Karunamurthy, Arivarasan, De Stefano, Danielle Vargas, Sander, Cindy, Kunning, Sheryl R, Najjar, Yana G, Davar, Diwakar, Luke, Jason J, Gooding, William, Bruno, Tullia C, Kirkwood, John M, Storkus, Walter J

“…Proinflammatory chemokines/cytokines support development and maturation of tertiary lymphoid structures (TLS) within the tumor microenvironment (TME). In the…”
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LAG-3 and PD-1 synergize on CD8 + T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity by Andrews, Lawrence P, Butler, Samuel C, Cui, Jian, Cillo, Anthony R, Cardello, Carly, Liu, Chang, Brunazzi, Erin A, Baessler, Andrew, Xie, Bingxian, Kunning, Sheryl R, Ngiow, Shin Foong, Huang, Yinghui Jane, Manne, Sasikanth, Sharpe, Arlene H, Delgoffe, Greg M, Wherry, E John, Kirkwood, John M, Bruno, Tulia C, Workman, Creg J, Vignali, Dario A A

“…Overcoming immune-mediated resistance to PD-1 blockade remains a major clinical challenge. Enhanced efficacy has been demonstrated in melanoma patients with…”
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Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer by Chuckran, Christopher A, Cillo, Anthony R, Moskovitz, Jessica, Overacre-Delgoffe, Abigail, Somasundaram, Ashwin S, Shan, Feng, Magnon, Grant C, Kunning, Sheryl R, Abecassis, Irina, Zureikat, Amer H, Luketich, James, Pennathur, Arjun, Sembrat, John, Rojas, Mauricio, Merrick, Daniel T, Taylor, Sarah E, Orr, Brian, Modugno, Francesmary, Buckanovich, Ron, Schoen, Robert E, Kim, Seungwon, Duvvuri, Umamaheswar, Zeh, Herbert, Edwards, Robert, Kirkwood, John M, Coffman, Lan, Ferris, Robert L, Bruno, Tullia C, Vignali, Dario A A

“…Despite the success of immune checkpoint blockade therapy, few strategies sufficiently overcome immunosuppression within the tumor microenvironment (TME)…”
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Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells by Shan, Feng, Cillo, Anthony R, Cardello, Carly, Yuan, Daniel Y, Kunning, Sheryl R, Cui, Jian, Lampenfeld, Caleb, Williams, Asia M, McDonough, Alexandra P, Pennathur, Arjun, Luketich, James D, Kirkwood, John M, Ferris, Robert L, Bruno, Tullia C, Workman, Creg J, Benos, Panayiotis V, Vignali, Dario A A

“…Human regulatory T cells (T ) are crucial regulators of tissue repair, autoimmune diseases, and cancer. However, it is challenging to inhibit the suppressive…”
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