Search Results - "Kunkel, J"

Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study by Wunderink, Richard G., Niederman, Michael S., Kollef, Marin H., Shorr, Andrew F., Kunkel, Mark J., Baruch, Alice, McGee, William T., Reisman, Arlene, Chastre, Jean

“…Background. Post hoc analyses of clinical trial data suggested that linezolid may be more effective than vancomycin for treatment of methicillin-resistant…”
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Chemokines and the Tissue-Specific Migration of Lymphocytes by Kunkel, Eric J, Butcher, Eugene C

“…Tissue-selective trafficking of memory and effector T and B lymphocytes is mediated by unique combinations of adhesion molecules and chemokines. The discovery…”
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The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells by Kunkel, Thaddeus J., Townsend, Alice, Sullivan, Kyle A., Merlet, Jean, Schuchman, Edward H., Jacobson, Daniel A., Lieberman, Andrew P.

“…The intracellular cholesterol transporter NPC1 functions in late endosomes and lysosomes to efflux unesterified cholesterol, and its deficiency causes…”
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Complicated Skin and Skin-Structure Infections and Catheter-Related Bloodstream Infections: Noninferiority of Linezolid in a Phase 3 Study by Wilcox, Mark H., Tack, Kenneth J., Bouza, Emilio, Herr, Daniel L., Ruf, Bernhard R., Ijzerman, M. Marian, Croos-Dabrera, Rodney V., Kunkel, Mark J., Knirsch, Charles

“…Background.Catheter-related bloodstream infection (CRBSI) causes substantial morbidity and mortality, but few randomized, controlled studies have been…”
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Systems biology in drug discovery by Butcher, Eugene C, Berg, Ellen L, Kunkel, Eric J

“…The hope of the rapid translation of 'genes to drugs' has foundered on the reality that disease biology is complex, and that drug development must be driven by…”
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Empowering Psychiatric Inpatients to Vote: Perceptions of Voting and the Barriers Encountered by Graziane, Julie A., Dalke, Katharine, Swigart, Alison, Pradhan, Sandeep, Zhu, Junjia, Laux, Thomas, Mikoluk, Cezary, Miller, Caitlin J., Luther, Joy, Kunkel, Elisabeth J. S.

“…Individuals with psychiatric illness believe that voting is important. However, these individuals have lower rates of voting when compared to the general…”
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A randomized, controlled trial of mindfulness-based art therapy (MBAT) for women with cancer by Monti, Daniel A., Peterson, Caroline, Kunkel, Elisabeth J. Shakin, Hauck, Walter W., Pequignot, Edward, Rhodes, Lora, Brainard, George C.

“…The purpose of this study was to gather data on the efficacy of a newly developed psychosocial group intervention for cancer patients, called mindfulness‐based…”
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Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy by Tice, Alan D., Rehm, Susan J., Dalovisio, Joseph R., Bradley, John S., Martinelli, Lawrence P., Graham, Donald R., Gainer, R. Brooks, Kunkel, Mark J., Yancey, Robert W., Williams, David N.

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Plasma-cell homing by Kunkel, Eric J, Butcher, Eugene C

“…Recent studies indicate that chemoattractant cytokines (chemokines), together with tissue-specific adhesion molecules, coordinate the migration of…”
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The scientific rationale and study protocol for the DPP3, Angiotensin II, and Renin Kinetics in Sepsis (DARK-Sepsis) randomized controlled trial: serum biomarkers to predict response to angiotensin II versus standard-of-care vasopressor therapy in the treatment of septic shock by Teixeira, J Pedro, Perez Ingles, David, Barton, Jordan B, Dean, James T, Garcia, Pablo, Kunkel, Susan J, Sarangarm, Preeyaporn, Weiss, Natalie K, Schaich, Christopher L, Busse, Laurence W, Nielsen, Nathan D

“…Data to support the use of specific vasopressors in septic shock are limited. Since angiotensin II (AT2) was approved by the Food and Drug Administration in…”
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A Common Mucosal Chemokine (Mucosae-Associated Epithelial Chemokine/CCL28) Selectively Attracts IgA Plasmablasts by Lazarus, Nicole H, Kunkel, Eric J, Johnston, Brent, Wilson, Eric, Youngman, Kenneth R, Butcher, Eugene C

“…IgA immunoblasts can seed both intestinal and nonintestinal mucosal sites following localized mucosal immunization, an observation that has led to the concept…”
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Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases by Schultz, Mark L, Fawaz, Maria V, Azaria, Ruth D, Hollon, Todd C, Liu, Elaine A, Kunkel, Thaddeus J, Halseth, Troy A, Krus, Kelsey L, Ming, Ran, Morin, Emily E, McLoughlin, Hayley S, Bushart, David D, Paulson, Henry L, Shakkottai, Vikram G, Orringer, Daniel A, Schwendeman, Anna S, Lieberman, Andrew P

“…Niemann-Pick disease type C is a fatal and progressive neurodegenerative disorder characterized by the accumulation of unesterified cholesterol in late…”
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Safety and efficacy of aminophylline in the prevention of bradyarrhythmia during coronary atherectomy by Nakhle, Asaad, Kunkel, Katherine J., Aqtash, Obadah, Zakhour, Samer, Brice, Lizbeth, Arnautovic, Jelena, Desai, Parth, Kaushik, Milan, Ferdinand, Keith, Alaswad, Khaldoon, Basir, Mir Babar

“…Coronary calcified lesions are commonly encountered and coronary atherectomy is commonly used for lesion modification during percutaneous coronary…”
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Efficacy and safety of linezolid versus vancomycin for the treatment of complicated skin and soft-tissue infections proven to be caused by methicillin-resistant Staphylococcus aureus by Itani, Kamal M.F., M.D., F.A.C.S, Dryden, Matthew S., M.D., F.R.C.P, Bhattacharyya, Helen, Ph.D, Kunkel, Mark J., M.D, Baruch, Alice M., M.D., Ph.D, Weigelt, John A., M.D., D.V.M., F.A.C.S

“…Abstract Background This open-label study compared oral or intravenous linezolid with intravenous vancomycin for treatment of complicated skin and soft-tissue…”
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Kinetics of Interleukin-6, Procalcitonin, and C-Reactive Protein After Pediatric Liver Transplantation by Zant, R, Melter, M, Knoppke, B, Ameres, M, Kunkel, J

“…Abstract In the early phase after pediatric liver transplantation (pLT) several concomitant factors may reduce the performance of established sepsis markers…”
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CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells by Kunkel, Eric J, Kim, Chang H, Lazarus, Nicole H, Vierra, Mark A, Soler, Dulce, Bowman, Edward P, Butcher, Eugene C

“…The dissemination of IgA-dependent immunity between mucosal sites has important implications for mucosal immunoprotection and vaccine development. Epithelial…”
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Papillary Muscle Rupture Due to Delayed STEMI Presentation in a Patient Self-Isolating for Presumed COVID-19 by Kunkel, Katherine J., Anwaruddin, Saif

“…A 57-year-old man acutely developed chest tightness and dyspnea. Given concern that his symptoms were consistent with COVID-19, the patient self-isolated…”
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The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells by Bowman, Edward P, Kuklin, Nelly A, Youngman, Kenneth R, Lazarus, Nicole H, Kunkel, Eric J, Pan, Junliang, Greenberg, Harry B, Butcher, Eugene C

“…Immunoglobulin A (IgA) provides protection against pathogens at mucosal surfaces. Chemotactic responses have been hypothesized to target IgA plasma cells…”
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Expression of the Chemokine Receptors CCR4, CCR5, and CXCR3 by Human Tissue-Infiltrating Lymphocytes by Kunkel, Eric J., Boisvert, Judie, Murphy, Kristine, Vierra, Mark A., Genovese, Mark C., Wardlaw, Andrew J., Greenberg, Harry B., Hodge, Martin R., Wu, Lijun, Butcher, Eugene C., Campbell, James J.

“…Differential expression of adhesion molecules and chemokine receptors has been useful for identification of peripheral blood memory lymphocyte subsets with…”
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Distinct Phenotype of E-Selectin-Deficient Mice: E-Selectin Is Required for Slow Leukocyte Rolling In Vivo by Kunkel, Eric J, Ley, Klaus

“…Leukocyte capture and rolling are mediated by calcium-dependent lectins expressed on most leukocytes (L-selectin) and the vascular endothelium (P- and…”
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