Search Results - "Kung, Jennifer E."

Structural Basis for the Non-catalytic Functions of Protein Kinases by Kung, Jennifer E., Jura, Natalia

“…Protein kinases are known primarily for their ability to phosphorylate protein substrates, which constitutes an essential biological process. Recently,…”
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Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells by Luoma, Adrienne M., Castro, Caitlin D., Mayassi, Toufic, Bembinster, Leslie A., Bai, Li, Picard, Damien, Anderson, Brian, Scharf, Louise, Kung, Jennifer E., Sibener, Leah V., Savage, Paul B., Jabri, Bana, Bendelac, Albert, Adams, Erin J.

“…The nature of the antigens recognized by γδ T cells and their potential recognition of major histocompatibility complex (MHC)-like molecules has remained…”
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Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization by Agnew, Christopher, Ayaz, Pelin, Kashima, Risa, Loving, Hanna S., Ghatpande, Prajakta, Kung, Jennifer E., Underbakke, Eric S., Shan, Yibing, Shaw, David E., Hata, Akiko, Jura, Natalia

“…Upon ligand binding, bone morphogenetic protein (BMP) receptors form active tetrameric complexes, comprised of two type I and two type II receptors, which then…”
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Prospects for pharmacological targeting of pseudokinases by Kung, Jennifer E., Jura, Natalia

“…Pseudokinases are members of the protein kinase superfamily but signal primarily through noncatalytic mechanisms. Many pseudokinases contribute to the…”
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The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor by López-Sagaseta, Jacinto, Kung, Jennifer E, Savage, Paul B, Gumperz, Jenny, Adams, Erin J

“…CD1d-mediated presentation of glycolipid antigens to T cells is capable of initiating powerful immune responses that can have a beneficial impact on many…”
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The pseudokinase TRIB1 toggles an intramolecular switch to regulate COP1 nuclear export by Kung, Jennifer E, Jura, Natalia

“…COP1 is a highly conserved ubiquitin ligase that regulates diverse cellular processes in plants and metazoans. Tribbles pseudokinases, which only exist in…”
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Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells by Luoma, Adrienne M, Castro, Caitlin D, Mayassi, Toufic, Bembinster, Leslie A, Bai, Li, Picard, Damien, Anderson, Brian, Scharf, Louise, Kung, Jennifer E, Sibener, Leah V, Savage, Paul B, Jabri, Bana, Bendelac, Albert, Adams, Erin J

“…The nature of the antigens recognized by gamma delta T cells and their potential recognition of major histocompatibility complex (MHC)-like molecules has…”
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PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization by Lopez, Mitchell L., Lo, Megan, Kung, Jennifer E., Dudkiewicz, Małgorzata, Jang, Gwendolyn M., Von Dollen, John, Johnson, Jeffrey R., Krogan, Nevan J., Pawłowski, Krzysztof, Jura, Natalia

“…Members of the New Kinase Family 3 (NKF3), PEAK1/SgK269 and Pragmin/SgK223 pseudokinases, have emerged as important regulators of cell motility and cancer…”
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Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor by López-Sagaseta, Jacinto, Sibener, Leah V, Kung, Jennifer E, Gumperz, Jenny, Adams, Erin J

“…Invariant Natural Killer T (iNKT) cells use highly restricted αβ T cell receptors (TCRs) to probe the repertoire of lipids presented by CD1d molecules. Here,…”
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The pseudokinase TRIB 1 toggles an intramolecular switch to regulate COP 1 nuclear export by Kung, Jennifer E, Jura, Natalia

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Abstract A023: Structural basis for regulation of MAPK signaling by DUSP5 and DUSP6 by Kung, Jennifer E., Sudhamsu, Jawahar

“…The Ras/mitogen-activated protein kinase (MAPK) cascade plays an essential role in several critical cellular processes, such as cell growth and proliferation,…”
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The Molecular Basis for Recognition of CD1d/[alpha]- Galactosylceramide by a Human Non-V[alpha]a24 T Cell Receptor by Lopez-Sagaseta, Jacinto, Kung, Jennifer E., Savage, Paul B., Gumperz, Jenny, Adams, Erin J.

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Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor: Lysophospholipid recognition by iNKT cells by López-Sagaseta, Jacinto, Sibener, Leah V, Kung, Jennifer E, Gumperz, Jenny, Adams, Erin J

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The Molecular Basis for Recognition of CD1d/[alpha]-Galactosylceramide by a Human Non-V[alpha]24 T Cell Receptor by López-Sagaseta, Jacinto, Kung, Jennifer E, Savage, Paul B, Gumperz, Jenny, Adams, Erin J

“…CD1d-mediated presentation of glycolipid antigens to T cells is capable of initiating powerful immune responses that can have a beneficial impact on many…”
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Crystal Structure of V[delta]1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human [gamma][delta] T Cells by Luoma, Adrienne M, Castro, Caitlin D, Mayassi, Toufic, Bembinster, Leslie A, Bai, Li, Picard, Damien, Anderson, Brian, Scharf, Louise, Kung, Jennifer E, Sibener, Leah V, Savage, Paul B, Jabri, Bana, Bendelac, Albert, Adams, Erin J

“…The nature of the antigens recognized by γδ T cells and their potential recognition of major histocompatibility complex (MHC)-like molecules has remained…”
Get full text