Search Results - "Kung, Hank"

PET/SPECT imaging agents for neurodegenerative diseases by Zhu, Lin, Ploessl, Karl, Kung, Hank F

“…Single photon emission computed tomography (SPECT) or positron emission computed tomography (PET) imaging agents for neurodegenerative diseases have a…”
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Head-to-head comparison of [68Ga]Ga-P16-093 and 2-[18F]FDG PET/CT in patients with clear cell renal cell carcinoma: a pilot study by Wang, Guochang, Li, Linlin, Wang, Jiarou, Zang, Jie, Chen, Jingci, Xiao, Yu, Fan, Xinrong, Zhu, Lin, Kung, Hank F., Zhu, Zhaohui

“…Purpose This pilot study was prospectively designed to evaluate and compare the diagnostic value of PET/CT using a PSMA-specific tracer [ 68 Ga]Ga-P16-093 and…”
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68Ga/177Lu-Labeled Bivalent Agents for Targeting Hypoxia and PSMA-Binding in Prostate Cancer by Luo, Yang, Jin, Wenbin, Wang, Ran, Zhao, Ruiyue, Zhu, Lin, Kung, Hank F.

“…Prostate-specific membrane antigen (PSMA) is an excellent target for cancer detection and therapy. Hypoxia is prevalent in solid tumors, and various…”
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68 Ga/ 177 Lu-Labeled Bivalent Agents for Targeting Hypoxia and PSMA-Binding in Prostate Cancer by Luo, Yang, Jin, Wenbin, Wang, Ran, Zhao, Ruiyue, Zhu, Lin, Kung, Hank F

“…Prostate-specific membrane antigen (PSMA) is an excellent target for cancer detection and therapy. Hypoxia is prevalent in solid tumors, and various…”
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The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing by Kung, Hank F

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Metabolic Imaging of Glutamine in Cancer by Zhu, Lin, Ploessl, Karl, Zhou, Rong, Mankoff, David, Kung, Hank F

“…Glucose and glutamine are the most abundant nutrients for producing energy and building blocks in normal and tumor cells. Increased glycolysis in tumors, the…”
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Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo by Venneti, Sriram, Dunphy, Mark P, Zhang, Hanwen, Pitter, Kenneth L, Zanzonico, Patrick, Campos, Carl, Carlin, Sean D, La Rocca, Gaspare, Lyashchenko, Serge, Ploessl, Karl, Rohle, Daniel, Omuro, Antonio M, Cross, Justin R, Brennan, Cameron W, Weber, Wolfgang A, Holland, Eric C, Mellinghoff, Ingo K, Kung, Hank F, Lewis, Jason S, Thompson, Craig B

“…Glucose and glutamine are the two principal nutrients that cancer cells use to proliferate and survive. Many cancers show altered glucose metabolism, which…”
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New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177) by Zha, Zhihao, Choi, Seok Rye, Li, Linlin, Zhao, Ruiyue, Ploessl, Karl, Yao, Xinyue, Alexoff, David, Zhu, Lin, Kung, Hank F.

“…Prostate-specific membrane antigen (PSMA) is a promising target for the diagnosis and radionuclide therapy of prostate cancer. This study reports conversion of…”
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Theranostic Agent Targeting Bone Metastasis: A Novel [68Ga]Ga/[177Lu]Lu-DOTA-HBED-bisphosphonate by Jin, Wenbin, Zhao, Ruiyue, Wang, Ran, Choi, Seok Rye, Ploessl, Karl, Alexoff, David, Wu, Zehui, Zhu, Lin, Kung, Hank F.

“…Bone metastasis in cancer patients is a major disease advancement for various types of cancer. Previously, [68Ga]­Ga-HBED-CC-bisphosphonate ([68Ga]­Ga-P15-041)…”
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Lu-177-Labeled Hetero-Bivalent Agents Targeting PSMA and Bone Metastases for Radionuclide Therapy by Zha, Zhihao, Ploessl, Karl, Choi, Seok Rye, Zhao, Ruiyue, Jin, Wenbin, Wang, Ran, Alexoff, David, Zhu, Lin, Kung, Hank F.

“…Prostate-specific membrane antigen (PSMA) is an excellent target for imaging and radionuclide therapy of prostate cancer. Recently, [177Lu]­Lu-PSMA-617…”
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Preclinical evaluation of [18F]D3FSP, deuterated AV-45, for imaging of β-amyloid in the brain by Zha, Zhihao, Ploessl, Karl, Choi, Seok Rye, Alexoff, David, Kung, Hank F.

“…Since the approval of three 18F labeled β-amyloid-targeting PET imaging agents, Amyvid (florbetapir f18, AV-45), Neuraceq (florbetaben f18, AV-1) and Vizamyl…”
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A prospective head-to-head comparison of [68Ga]Ga-P16-093 and [68Ga]Ga-PSMA-11 PET/CT in patients with primary prostate cancer by Wang, Guochang, Li, Linlin, Zhu, Ming, Zang, Jie, Wang, Jiarou, Wang, Rongxi, Yan, Weigang, Zhu, Lin, Kung, Hank F., Zhu, Zhaohui

“…Purpose We aimed to compare the diagnostic performance and biodistribution of two similar PET agents, [ 68 Ga]Ga-P16-093 and [ 68 Ga]Ga-PSMA-11, in the same…”
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Synthesis and Evaluation of 68Ga- and 177Lu-Labeled (R)- vs (S)‑DOTAGA Prostate-Specific Membrane Antigen-Targeting Derivatives by Zhao, Ruiyue, Ploessl, Karl, Zha, Zhihao, Choi, Seokrye, Alexoff, David, Zhu, Lin, Kung, Hank F

“…Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer cells and therefore is an attractive target for prostate cancer diagnosis and…”
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Serotonin transporter imaging agent as a probe for β-cells of pancreas by Sun, Yuli, Li, Guangwen, Hong, Haiyan, Zhu, Lin, Kung, Hank F., Zhang, Yan, Zhu, Jinxia

“…Diabetes mellitus (DM) is one of the major diseases in the world. Nuclear medicine imaging may be able to detect functional status of pancreatic β cells in…”
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Head-to-head comparison of [68 Ga]Ga-P16-093 and [68 Ga]Ga-PSMA-617 in dynamic PET/CT evaluation of the same group of recurrent prostate cancer patients by Wang, Guochang, Hong, Haiyan, Zang, Jie, Liu, Qingxing, Jiang, Yuanyuan, Fan, Xinrong, Zhu, Zhaohui, Zhu, Lin, Kung, Hank F.

“…Purpose This study was prospectively designed to evaluate the early dynamic organ distribution and tumor detection capability of [ 68  Ga]Ga-P16-093, which was…”
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Synthesis and evaluation of a novel urea-based 68Ga-complex for imaging PSMA binding in tumor by Zha, Zhihao, Ploessl, Karl, Choi, Seok Rye, Wu, Zehui, Zhu, Lin, Kung, Hank F.

“…Prostate specific membrane antigen (PSMA) is a well-established target for diagnostic and therapeutic applications for prostate cancer. It is know that…”
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Novel [68Ga/177Lu]Ga/Lu-AZ-093 as PSMA-Targeting Agent for Diagnosis and Radiotherapy by Wang, Ran, Jin, Wenbin, Luo, Yang, Hong, Haiyan, Zhao, Ruiyue, Li, Linlin, Yan, Li, Qiao, Jinping, Ploessl, Karl, Zhu, Lin, Kung, Hank F.

“…Prostate-specific membrane antigen (PSMA) overexpressed in prostate cancer cells can serve as a target for imaging and radioligand therapy (RLT). Previously,…”
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5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants by Richardson-Jones, Jesse W, Craige, Caryne P, Guiard, Bruno P, Stephen, Alisson, Metzger, Kayla L, Kung, Hank F, Gardier, Alain M, Dranovsky, Alex, David, Denis J, Beck, Sheryl G, Hen, René, Leonardo, E David

“…Most depressed patients don't respond to their first drug treatment, and the reasons for this treatment resistance remain enigmatic. Human studies implicate a…”
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Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093 by Zha, Zhihao, Choi, Seok Rye, Ploessl, Karl, Alexoff, David, Zhao, Ruiyue, Zhu, Lin, Kung, Hank F

“…Prostate-specific membrane antigen (PSMA)-targeted radioligands have played an increasing role in the diagnosis of prostate cancer. [68Ga]­Ga-P16-093 is a…”
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A New [68Ga]Ga-HBED-CC-Bisphosphonate as a Bone Imaging Agent by Zha, Zhihao, Wu, Zehui, Choi, Seok Rye, Ploessl, Karl, Smith, Megan, Alexoff, David, Zhu, Lin, Kung, Hank F

“…Positron emission tomography (PET) imaging using 68Ga-labeled bisphosphonates to target bone metastasis could be a valuable tool in cancer diagnosis and…”
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