Search Results - "Kung, H. F."
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Vascular control by infrarenal aortic cross‐clamping in placenta accreta spectrum disorders: description of technique
Published in BJOG : an international journal of obstetrics and gynaecology (01-05-2021)“…We describe a novel surgical technique in 31 women with histopathologically confirmed placenta accreta spectrum (PAS) disorders managed by a multidisciplinary…”
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MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of β-catenin signaling
Published in Annals of oncology (01-11-2014)“…Distant metastasis is the major cause of cancer-related death, and epithelial-to-mesenchymal transition (EMT) has a critical role in this process. Accumulating…”
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EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1 HDAC2 and Snail to inhibit E-cadherin
Published in Oncogene (02-02-2012)“…The enhancer of zeste homolog 2 (EZH2) is upregulated and has an oncogenic role in several types of human cancer. However, the abnormalities of EZH2 and its…”
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Authors' response Re: Some concerns regarding aortic cross‐clamping in caesarean hysterectomy for placenta accreta spectrum (Re: Vascular control by infrarenal aortic cross‐clamping in placenta accreta spectrum disorders: description of technique; something old, something new & something borrowed)
Published in BJOG : an international journal of obstetrics and gynaecology (01-08-2021)Get full text
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Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients
Published in Oncogene (19-07-2012)“…Using genome-wide methylation screening, we identified that paired box gene 5 ( PAX5 ) is involved in human cancer development. However, the function of PAX5…”
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Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation
Published in Oncogene (05-01-2012)“…Telomere maintenance is essential for cancer growth. Induction of telomere dysfunction, for example, by inhibition of telomeric proteins or telomerase, has…”
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Overexpression of AIB1 negatively affects survival of surgically resected non-small-cell lung cancer patients
Published in Annals of oncology (01-08-2010)“…The amplified in breast cancer 1 (AIB1) gene has been considered to play an oncogenic role in human cancers, but its clinical/prognostic significance in…”
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Low expression of Mel-18 predicts poor prognosis in patients with breast cancer
Published in Annals of oncology (01-12-2010)“…Our previous study suggested that melanoma nuclear protein 18 (Mel-18) acted as a tumor suppressor in human breast cancer. This study was designed to…”
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Behavioral and biochemical studies of total furocoumarins from seeds of Psoralea corylifolia in the chronic mild stress model of depression in mice
Published in Phytomedicine (Stuttgart) (01-08-2007)“…Depression is related to alterations of the monoamine oxidase (MAO), hypothalamic–pituitary–adrenal (HPA) axis, and oxidative systems, and some antidepressants…”
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Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment
Published in European Journal of Nuclear Medicine (01-10-2000)“…Involvement of the dopaminergic system has been suggested in patients suffering from attention deficit hyperactivity disorder (ADHD) since the symptoms can be…”
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Radioiodinated Styrylbenzenes and Thioflavins as Probes for Amyloid Aggregates
Published in Journal of medicinal chemistry (07-06-2001)“…We report for the first time that small molecule-based radiodiodinated ligands, showing selective binding to Aβ aggregates, cross the intact blood−brain…”
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Filtering of Ineffective siRNAs and Improved siRNA Design Tool
Published in Bioinformatics (15-01-2005)“…Motivation: Short interfering RNAs (siRNAs) can be used to suppress gene expression and possess many potential applications in therapy, but how to design an…”
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Gene therapy for new bone formation using adeno-associated viral bone morphogenetic protein-2 vectors
Published in Gene therapy (01-08-2003)“…Previous reports have suggested that bone morphogenetic protein (BMP) gene therapy could be applied for in vivo bone regeneration. However, these studies were…”
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Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography
Published in Neuroscience letters (12-05-2000)“…Ten previously untreated adults with attention deficit hyperactivity disorder (ADHD) were investigated before and after 4 weeks of treatment with a dose of 3×5…”
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Phase I trial of a human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma
Published in Journal of clinical oncology (01-06-1998)“…To evaluate the toxicity, immunogenicity, and pharmacokinetics of a human-mouse chimeric monoclonal antibody (mAb) ch 14.18 directed against disialoganglioside…”
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Localization of 5-HT1A and 5-HT2A positive cells in the brainstems of control age-matched and Alzheimer individuals
Published in AGE (01-12-2010)“…Serotonin receptor 1A and 2A positive cells in postmortem brainstems were demonstrated via immunohistochemistry in eight control age-matched elderly…”
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Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2
Published in Oncogene (12-03-2015)“…Emerging evidence has shown that cancer stem cells (CSCs) are the cellular determinants to promote cancer invasion and metastasis. However, the mechanism…”
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SPECT Imaging of Striatal Dopamine Release after Amphetamine Challenge
Published in The Journal of nuclear medicine (1978) (01-07-1995)“…This study assesses the feasibility of using SPECT to image intrasynaptic dopamine release in human striatum following dextroamphetamine sulfate…”
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Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy
Published in Cancer gene therapy (01-11-2008)“…The low in vivo transduction efficiency of recombinant adeno-associated virus (rAAV) and the undesirably strong immunogenicity of adenovirus (rAdv) have…”
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