Search Results - "Kunert, R."
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Advanced approach for oxygen transport and crystallization front calculation in Cz silicon crystal growth
Published in Journal of crystal growth (01-04-2022)“…•STR model accounts for anisotropy of normal Reynolds stresses.•STR model predicts Oxygen profiles in Cz 8″ Silicon crystals with 10% accuracy.•Computer…”
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Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization
Published in Protein engineering, design and selection (01-07-2018)“…Abstract Humanized monoclonal antibodies (mAbs) are among the most promising modern therapeutics, but defined engineering strategies are still not available…”
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Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
Published in Immunity (Cambridge, Mass.) (01-02-2005)“…Broadly neutralizing monoclonal antibodies to HIV-1 are rare but invaluable for vaccine design. 4E10 is the broadest neutralizing antibody known and recognizes…”
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Humanization strategies for an anti-idiotypic antibody mimicking HIV-1 gp41
Published in Protein engineering, design and selection (01-12-2010)“…Anti-idiotypic antibodies could represent an alternative vaccination approach in human therapy. The anti-idiotypic antibody Ab2/3H6 was generated in mouse and…”
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plant-derived human monoclonal antibody induces an anti-carbohydrate immune response in rabbits
Published in Glycobiology (Oxford) (01-03-2008)“…A common argument against using plants as a production system for therapeutic proteins is their inability to perform authentic N-glycosylation. A major concern…”
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Quality matters – Is IgM production influenced by external process conditions?
Published in New biotechnology (10-10-2018)Get full text
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P04-03. Cross-clade neutralization analysis of plasmas from clade B, C and CRF01_AE HIV-infected donors
Published in Retrovirology (22-10-2009)“…From: AIDS Vaccine 2009 Paris, France 19-22 October 2009 Author details 1-AIDS/Viral Immunology, Torrey Pines Institute, San Diego, CA, USAEMPTY 2-MonoGramBio,…”
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Kinetic Monte Carlo simulation of formation of microstructures in liquid droplets
Published in New journal of physics (12-11-2004)Get full text
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Inhomogeneous charging and screening effects in semiconductor quantum dot arrays
Published in New journal of physics (09-07-2004)“…The electronic properties of quantum dot (QD) arrays are strongly influenced by the Coulomb interaction of electrons within the dot as well as with those in…”
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Making the strange more familiar: Influence of germinality content on mAb expression potentials and thermal stability properties
Published in New biotechnology (10-10-2018)Get full text
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Inefficient CAR-proximal signaling blunts antigen sensitivity
Published in Nature immunology (01-08-2020)“…Rational design of chimeric antigen receptors (CARs) with optimized anticancer performance mandates detailed knowledge of how CARs engage tumor antigens and…”
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Evaluation of Atmospheric and Vacuum Residues Using Molecular Distillation and Optimization
Published in Petroleum science and technology (01-03-2006)“…The term atmospheric residue describes the material at the bottom of the atmospheric distillation tower having a lower boiling point limit of about 340°C; the…”
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Journal Article Conference Proceeding -
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Nonconventional Therapeutic Protocol for Type III Dens Invaginatus
Published in The journal of contemporary dental practice (01-03-2017)“…This study discusses a nonconventional therapeutic protocol for type III dens invaginatus. This condition is a disorder of dental development, caused by the…”
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14
True Boiling Point Extended Curve of Vacuum Residue Through Molecular Distillation
Published in Petroleum science and technology (01-03-2006)“…Molecular distillation is a separation process that explores high vacuum, operation at reduced temperatures, and low exposition of the material at the…”
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Journal Article Conference Proceeding -
15
Understanding the heterologous expression of HIV-1 Env glycoproteins in CHO Cells
Published in New biotechnology (10-10-2018)Get full text
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Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies
Published in Journal of Virology (01-12-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
Published in Science (American Association for the Advancement of Science) (24-06-2005)“…The design of a human immunodeficiency virus-1 (HIV-1) immunogen that can induce broadly reactive neutralizing antibodies is a major goal of HIV-1 vaccine…”
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Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1
Published in Journal of Virology (01-01-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of Increased Expression of Protein Disulfide Isomerase and Heavy Chain Binding Protein on Antibody Secretion in a Recombinant CHO Cell Line
Published in Biotechnology progress (2005)“…Previous work has shown that a human‐antibody‐producing recombinant CHO cell line did not increase its intracellular content of protein disulfide isomerase…”
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Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition
Published in Science (American Association for the Advancement of Science) (27-06-2003)“…Human antibody 2G12 neutralizes a broad range of human immunodeficiency virus type 1 (HIV-1) isolates by binding an unusually dense cluster of carbohydrate…”
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