Search Results - "Kundik, Arkadi"
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Ascaris suum excretory/secretory products differentially modulate porcine dendritic cell subsets
Published in Frontiers in immunology (10-11-2022)“…Helminths produce excretory/secretory products (E/S) which can modulate the immune responses of their hosts. Dendritic cells (DC) are essential for initiating…”
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Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection
Published in Scientific reports (28-06-2024)“…Helminth infections lead to an overdispersion of the parasites in humans as well as in animals. We asked whether early immune responses against migrating…”
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Acute Ascaris infection impairs the effector functions of natural killer cells in single and Salmonella co-infected pigs
Published in Scientific reports (25-06-2024)“…Natural killer (NK) cells play a key role in defense against Salmonella infections during the early phase of infection. Our previous work showed that the…”
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Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction
Published in Parasites & vectors (19-07-2023)“…Helminth infections are an important public health problem in humans and have an even greater impact on domestic animal and livestock welfare. Current readouts…”
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Ascaris suum infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion
Published in Frontiers in immunology (2024)“…spp. undergo extensive migration within the body before establishing patent infections in the small intestinal tract of humans and pigs. However, whether…”
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Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host
Published in Microbiome (16-12-2022)“…Intestinal helminths are extremely prevalent among humans and animals. In particular, intestinal roundworms affect more than 1 billion people around the globe…”
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Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs
Published in mSphere (25-09-2024)“…is one of the most widespread helminth infections, leading to chronic morbidity in humans and considerable economic losses in pig farming. In addition, pigs…”
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