Search Results - "Kummer, Sandra"

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    WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage by Porebski, Bartlomiej, Wild, Sebastian, Kummer, Sandra, Scaglione, Sarah, Gaillard, Pierre-Henri L., Gari, Kerstin

    Published in iScience (22-11-2019)
    “…During DNA replication stress, stalled replication forks need to be stabilized to prevent fork collapse and genome instability. The AAA + ATPase WRNIP1 (Werner…”
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    Journal Article
  3. 3

    The conscientiousness-health link in depression: Results from a path analysis by Kummer, Sandra, Dalkner, Nina, Schwerdtfeger, Andreas, Hamm, Carlo, Schwalsberger, Karin, Reininghaus, Bernd, Krammer, Georg, Reininghaus, Eva

    Published in Journal of affective disorders (01-12-2021)
    “…•Path analyses of conscientiousness, health risk behaviors and indicators of health.•Large clinical sample with depressive symptomatology.•Less conscientious…”
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    Journal Article
  4. 4

    The protein landscape of chronic lymphocytic leukemia by Meier-Abt, Fabienne, Lu, Junyan, Cannizzaro, Ester, Pohly, Marcel F., Kummer, Sandra, Pfammatter, Sibylle, Kunz, Laura, Collins, Ben C., Nadeu, Ferran, Lee, Kwang Seok, Xue, Peng, Gwerder, Myriam, Roiss, Michael, Hüllein, Jennifer, Scheinost, Sebastian, Dietrich, Sascha, Campo, Elias, Huber, Wolfgang, Aebersold, Ruedi, Zenz, Thorsten

    Published in Blood (16-12-2021)
    “…Many functional consequences of mutations on tumor phenotypes in chronic lymphocytic leukemia (CLL) are unknown. This may be in part due to a scarcity of…”
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    Journal Article
  5. 5

    Human DNA polymerase delta requires an iron-sulfur cluster for high-fidelity DNA synthesis by Jozwiakowski, Stanislaw K, Kummer, Sandra, Gari, Kerstin

    Published in Life science alliance (01-08-2019)
    “…Replication of eukaryotic genomes relies on the family B DNA polymerases Pol α, Pol δ, and Pol ε. All of these enzymes coordinate an iron-sulfur (FeS) cluster,…”
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    Journal Article
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    Lymphoma and Leukemia Cell Vulnerabilities and Resistance Identified by Compound Library Screens by Tomska, Katarzyna, Scheinost, Sebastian, Kivioja, Jarno, Kummer, Sandra, Do, Thi Huong Lan, Zenz, Thorsten

    “…Response to anticancer agents is often restricted to subsets of patients. Recognition of factors underlying this heterogeneity and identification of biomarkers…”
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    Journal Article
  7. 7

    The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation by Simon, Anna K, Kummer, Sandra, Wild, Sebastian, Lezaja, Aleksandra, Teloni, Federico, Jozwiakowski, Stanislaw K, Altmeyer, Matthias, Gari, Kerstin

    Published in Life science alliance (01-03-2020)
    “…The iron-sulfur (FeS) cluster helicase DDX11 is associated with a human disorder termed Warsaw Breakage Syndrome. Interestingly, one disease-associated…”
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    Journal Article
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    The iron–sulphur cluster in human DNA2 is required for all biochemical activities of DNA2 by Mariotti, Laura, Wild, Sebastian, Brunoldi, Giulia, Piceni, Alessandra, Ceppi, Ilaria, Kummer, Sandra, Lutz, Richard E., Cejka, Petr, Gari, Kerstin

    Published in Communications biology (23-06-2020)
    “…The nuclease/helicase DNA2 plays important roles in DNA replication, repair and processing of stalled replication forks. DNA2 contains an iron-sulphur (FeS)…”
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    Journal Article
  10. 10

    Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells by Tan, Ge, Wolski, Witold E., Kummer, Sandra, Hofstetter, Mara, Theocharides, Alexandre P.A., Manz, Markus G., Aebersold, Ruedi, Meier-Abt, Fabienne

    Published in Blood advances (14-06-2022)
    “…Polycythemia vera (PV) is a stem cell disorder characterized by hyperproliferation of the myeloid lineages and the presence of an activating JAK2 mutation. To…”
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    Journal Article