Search Results - "Kumiko Noda"

A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its active form, {4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic acid (MRE-269), on rat pulmonary artery by Kuwano, Keiichi, Hashino, Asami, Noda, Kumiko, Kosugi, Keiji, Kuwabara, Kenji

“…2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304) is an orally available, long-acting nonprostanoid prostacyclin…”
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Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis by Nozawa, Takashi, Nakajima, Miki, Tamai, Ikumi, Noda, Kumiko, Nezu, Jun-Ichi, Sai, Yoshimichi, Tsuji, Akira, Yokoi, Tsuyoshi

“…Genetic polymorphisms of human organic anion transporting polypeptides OATP-C (SLC21A6) and OATP-B (SLC21A9) in the Japanese population were analyzed. The…”
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The Relationship between the Plasma Concentration of Bepridil and Its Efficacy in the Treatment of Atrial Fibrillation in Japanese Patients by Noda, Kumiko, Gotoh, Yoshikazu, Tanioka, Satoru, Narayama, Yasuhiro, Kobayashi, Michiya, Iwai, Shinji, Katoh, Noriyoshi, Tadano, Koji

“…Bepridil hydrochloride is used for treatment of atrial fibrillation (AF) in Japan. We investigated the relationship between plasma concentrations of bepridil…”
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Inhibitions of urinary oxidative stress and renal calcium level by an extract of Quercus salicina Blume/Quercus stenophylla Makino in a rat calcium oxalate urolithiasis model by Moriyama, Manabu T, Suga, Koudai, Miyazawa, Katsuhito, Tanaka, Tatsuro, Higashioka, Masaya, Noda, Kumiko, Oka, Michiko, Tanaka, Mitsushi, Suzuki, Koji

“…Objectives:  To clarify the mechanism of Urocalun, an extract of Quercus salicina Blume/Quercus stenophylla Makino (QS), in the treatment of urolithiasis…”
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A Critical Role of c-Cbl-Interacting Protein of 85 kDa in the Development and Progression of Head and Neck Squamous Cell Carcinomas through the Ras-ERK Pathway by Wakasaki, Takahiro, Masuda, Muneyuki, Niiro, Hiroaki, Jabbarzadeh-Tabrizi, Siamak, Noda, Kumiko, Taniyama, Tadayoshi, Komune, Shizuo, Akashi, Koichi

“…Activation of the transforming growth factor (TGF) α/epidermal growth factor receptor (EGFR)-mediated signaling pathway is a common mechanism for dysregulated…”
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CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells by Niiro, Hiroaki, Jabbarzadeh-Tabrizi, Siamak, Kikushige, Yoshikane, Shima, Takahiro, Noda, Kumiko, Ota, Shun-ichiro, Tsuzuki, Hirofumi, Inoue, Yasushi, Arinobu, Yojiro, Iwasaki, Hiromi, Shimoda, Shinji, Baba, Eishi, Tsukamoto, Hiroshi, Horiuchi, Takahiko, Taniyama, Tadayoshi, Akashi, Koichi

“…The aberrant regulation of B-cell receptor (BCR) signaling allows unwanted B cells to persist, thereby potentially leading to autoimmunity and B-cell…”
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Relevance of anti-reactive oxygen species activity to anti-inflammatory activity of components of Eviprostat ®, a phytotherapeutic agent for benign prostatic hyperplasia by Oka, Michiko, Tachibana, Masaki, Noda, Kumiko, Inoue, Naoki, Tanaka, Mitsushi, Kuwabara, Kenji

“…Inflammation is a common finding in benign prostatic hyperplasia (BPH). The phytotherapeutic agent eviprostat is a popular treatment for BPH in Japan and…”
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Determination and Bioimaging Method for Nitric Oxide in Biological Specimens by Diaminofluorescein Fluorometry by Itoh, Yoshinori, Ma, Fu Hai, Hoshi, Hanae, Oka, Michiko, Noda, Kumiko, Ukai, Yojiro, Kojima, Hirotatsu, Nagano, Tetsuo, Toda, Noboru

“…A simple and sensitive assay and a cellular bioimaging method for nitric oxide (NO) were developed using a novel diaminofluorescein DAF-FM and its diacetate…”
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Structural features of phenoxycarbonylimino neonicotinoids acting at the insect nicotinic receptor by Ohno, Ikuya, Tomizawa, Motohiro, Miyazu, Nozomi, Kushibiki, Gohito, Noda, Kumiko, Hasebe, Yasunori, Durkin, Kathleen A., Miyake, Taiji, Kagabu, Shinzo

“…A structure–activity relationship study of phenoxycarbonylimino neonicotinoids leads to establish in silico binding site interaction model featuring that the…”
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A Liquid Chromatographic Method for Quantifying Unbound Micafungin in Human Plasma and the Relationship between the Concentrations of Unbound and Total Micafungin in Plasma by Noda, Kumiko, Yokoyama, Toshinori, Akiyama, Yasushi, Tadano, Koji

“…This report describes a modified method for the quantitative determination of unbound micafungin (MCFG) in human plasma that is unrelated to chemical methods…”
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Irsogladine Prevents Monochloramine-Induced Gastric Mucosal Lesions by Improving the Decrease in Mucosal Blood Flow Due to the Disturbance of Nitric Oxide Synthesis in Rats by Kyoi, Takashi, Oka, Michiko, Noda, Kumiko, Ukai, Yojiro

“…The inhibitory effect of an anti-ulcer drug irsogladine [2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate] on monochloramine (NH2Cl)-induced gastric…”
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Phosphodiesterase inhibition by a gastroprotective agent irsogladine: Preferential blockade of cAMP hydrolysis by Kyoi, Takashi, Oka, Michiko, Noda, Kumiko, Ukai, Yojiro

“…The effect of irsogladine [2,4-diamino-6-(2,5-dichlorophenyl)- s-triazine maleate], an antiulcer drug, on contents of cyclic nucleotides including cAMP and…”
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GENETIC POLYMORPHISMS OF CYP2C8 IN JAPANESE POPULATION by NAKAJIMA, Miki, FUJIKI, Yuto, NODA, Kumiko, OHTSUKA, Hiroki, OHKUNI, Hisashi, KYO, Satoru, INOUE, Masaki, KUROIWA, Yukio, YOKOI, Tsuyoshi

“…CYP2C8 plays important roles in metabolizing therapeutic drugs and endogenous compounds. Although genetic polymorphisms of CYP2C8 were reported, there is…”
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Functional role of inhibitory and excitatory nerves in the porcine lower urinary tract by Noda, Kumiko, Takebe, Mika, Oka, Michiko, Hirouchi, Masaaki, Ukai, Yojiro, Toda, Noboru

“…In the trigone (three portions) and proximal urethra isolated from castrated male pigs, transmural electrical stimulation (0.5–10 Hz) induced no or slight…”
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Errate: A Retrospective Study of 290 Patients with Resectable Benign and Malignant Gastric Neoplasms to Compare Postoperative Outcomes of Endoscopic Resection with and without the Internal Traction Method Using a Spring-and-Loop with Clip (S-O Clip) by Nakatsu, Yoichi, Furihata, Makoto, Fujiyama, Anna, Yuzawa, Arisa, Ushio, Mako, Yano, Shintaro, Okawa, Hiroki, Noda, Kumiko, Nishi, Shinjiro, Ogiwara, Shingo, Kitamura, Tsuneo, Sakamoto, Naoto, Osada, Taro

“…The authors have identified an error in Table 5 concerning the dissection speed. It is currently listed as follows: S-O group 14.5±9.5 and Control group…”
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A Retrospective Study of 290 Patients with Resectable Benign and Malignant Gastric Neoplasms to Compare Postoperative Outcomes of Endoscopic Resection with and without the Internal Traction Method Using a Spring-and-Loop with Clip (S-O Clip) by Nakatsu, Yoichi, Furihata, Makoto, Fujiyama, Anna, Yuzawa, Arisa, Ushio, Mako, Yano, Shintaro, Okawa, Hiroki, Noda, Kumiko, Nishi, Shinjiro, Ogiwara, Shingo, Kitamura, Tsuneo, Sakamoto, Naoto, Osada, Taro

“…BACKGROUND The spring-and-loop with clip (S-O clip) consists of a spring and a nylon loop located on one side of the claws of the clip, and is used in gastric…”
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Irsogladine Prevents Monochloramine-Induced Gastric Mucosal Lesions by Improving the Decrease in Mucosal Blood Flow Due to the Disturbance of Nitric Oxide Synthesis in Rats by Kyoi, Takashi, Oka, Michiko, Noda, Kumiko, Ukai, Yojiro

“…The inhibitory effect of an anti-ulcer drug irsogladine [2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate] on monochloramine (NH2Cl)-induced gastric…”
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Transgastric Jejunostomy (PEG-J) for Continuous Infusion of Levodopa-Carbidopa Intestinal Gel: An Approach for Parkinson's Disease Treatment by Nomoto, Yusuke, Furihata, Makoto, Hagiwara, Haruka, Ishino, Hirotaka, Yano, Shintaro, Okawa, Hiroki, Nakatsu, Yoichi, Noda, Kumiko, Nishi, Shinjiro, Ogiwara, Shingo, Kitamura, Tsuneo, Osada, Taro

“…BACKGROUND Parkinson's disease (PD) is a neurodegenerative disorder that often requires long-term management of motor symptoms. Continuous infusion of…”
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Transgastric Jejunostomy (PEG-J) for Continuous Infusion of Levodopa-Carbidopa Intestinal Gel: An Approach for Parkinson\'s Disease Treatment by Nomoto, Yusuke, Furihata, Makoto, Hagiwara, Haruka, Ishino, Hirotaka, Yano, Shintaro, Okawa, Hiroki, Nakatsu, Yoichi, Noda, Kumiko, Nishi, Shinjiro, Ogiwara, Shingo, Kitamura, Tsuneo, Osada, Taro

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Anti-ulcer drug irsogladine prevents monochioramine-induced gastric mucosal lesions by reversal of the decrease in mucosal blood flow due to the disturbance of NO synthesis in rats by Kumiko Noda, Michiko Oka, Takashi Kyoi, Yojiro Ukai

“…The effect of irsogladine [2, 4-diamino-6- (2, 5-dichiorophenyl) -s-triazine maleate] on monochioramine-induced gastric mucosal lesions was examined in rats…”
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