Search Results - "Kumble, Sumukh"
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Targeting membrane proteins for antibody discovery using phage display
Published in Scientific reports (18-05-2016)“…A critical factor in the successful isolation of new antibodies by phage display is the presentation of a correctly folded antigen. While this is relatively…”
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Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial
Published in PloS one (14-07-2021)“…Diabetes mellitus is associated with inadequate delivery of oxygen to tissues. Cellular hypoxia is associated with mitochondrial dysfunction which increases…”
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Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets
Published in Expert opinion on drug delivery (01-09-2020)“…Monoclonal antibodies have been utilized in clinical and basic research for the treatment of various malignancies. Whilst all therapeutically approved…”
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Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach
Published in mAbs (19-05-2018)“…Antibodies are routinely used to study the activity of transcription factors, using various in vitro and in vivo approaches such as electrophoretic mobility…”
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