Search Results - "Kumbhare, Ravindra M."

Synthesis and cytotoxic evaluation of thiourea and N-bis-benzothiazole derivatives: A novel class of cytotoxic agents by Kumbhare, Ravindra M., Dadmal, Tulshiram, Kosurkar, Umesh, Sridhar, V., Rao, J. Venkateswara

“…Benzothiazolyl thiocarbamides has been achieved using a catalytic amount of 4-dimethylaminopyridine (DMAP) followed by its chemoselective oxidative cyclization…”
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Synthesis and biological evaluation of novel Mannich bases of 2-arylimidazo[2,1- b]benzothiazoles as potential anti-cancer agents by Kumbhare, Ravindra M., Vijay Kumar, K., Janaki Ramaiah, M., Dadmal, Tulshiram, Pushpavalli, S.N.C.V.L., Mukhopadhyay, Debasmita, Divya, B., Anjana Devi, T., Kosurkar, Umesh, Pal-Bhadra, Manika

“…A new series of Mannich bases of 2-arylimidazo[2,1- b]benzothiazoles were synthesized and evaluated for their anti-cancer activity. These compounds showed…”
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Synthesis and biological evaluation of novel 2-imino-4-thiazolidinone derivatives as potent anti-cancer agents by Appalanaidu, K., Kotcherlakota, Rajesh, Dadmal, T.L., Bollu, Vishnu Sravan, Kumbhare, Ravindra M., Patra, Chitta Ranjan

“…[Display omitted] A new series of 2-imino-4-thiazolidinone derivatives (7a–7t) has been synthesised and screened for their cytotoxicity against three cancer…”
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Synthesis and study the antimicrobial activity of novel 2-(1H-indol-3-yl)- N-(3, 4-diphenylthiazol-2(3H)-ylidene) ethanamine derivatives by Kumbhare, Ravindra M, Kumar, K Vijay, Dadmal, Tulshiram L, Kosurkar, Umesh B, Appalanaidu, K

“…A series of novel 2-(1H-indol-3-yl)-N-(3, 4-diphenylthiazol-2(3H)-ylidene) ethanamine derivatives (5a-o) were synthesized by cyclization of corresponding…”
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Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents by Kumbhare, Ravindra M., Kosurkar, Umesh B., Janaki Ramaiah, M., Dadmal, Tulshiram L., Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika

“…A new series of isoxazoles and triazoles linked 2-phenyl benzothiazole were synthesized and evaluated for their anticancer activity. These compounds have been…”
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Benzimidazole-1,2,3-triazole hybrid molecules: synthesis and study of their interaction with G-quadruplex DNA by Singu, Padma S, Chilakamarthi, Ushasri, Mahadik, Namita S, Keerti, Bhamidipati, Valipenta, Narasimhulu, Mokale, Santosh N, Nagesh, Narayana, Kumbhare, Ravindra M

“…A series of new benzimidazole-1,2,3-triazole hybrid derivatives have been synthesized via 'click' reaction and evaluated for their in vitro cytotoxicity as…”
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Effect of Benzothiazole based conjugates in causing apoptosis by Regulating p53, PTEN and MAP Kinase proteins affecting miR-195a and miR-101-1 by Pushpavalli, Sncvl, Ramaiah, M Janaki, Srinivas, Ch, Mukhopadhya, Debasmita, Aditya, J L, Kumbhare, Ravindra M, Bhadra, Utpal, Bhadra, Manika Pal

“…Hepatocellular carcinoma (HCC) accounts for majority of liver cancers and is the leading cause of cancer related death in Asia. Like any other cancer, HCC…”
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Synthesis and anticancer evaluation of novel triazole linked N-(pyrimidin-2-yl)benzo[d]thiazol-2-amine derivatives as inhibitors of cell survival proteins and inducers of apoptosis in MCF-7 breast cancer cells by Kumbhare, Ravindra M., Dadmal, Tulshiram L., Ramaiah, M. Janaki, Kishore, K.S.V., Pushpa Valli, S.N.C.V.L., Tiwari, Sudheer Kumar, Appalanaidu, K., Rao, Y. Khageswar, Bhadra, Manika pal

“…[Display omitted] •A series of novel triazole linked N-(pyrimidin-2yl)benzo[d]thiazol-2-amine derivatives were synthesized.•Synthesized compounds were…”
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One-Pot Synthesis of 2-Imino-4-(trifluoromethyl)thiazolidin-4-ol Derivatives in a Three-Component Reaction: Application to Structurally Diverse Scaffolds of Biological Interest Through Subsequent Reactions by Dalmal, Tulshiram, Appalanaidu, K., Kosurkar, Umesh B., Jagadeesh Babu, N., Kumbhare, Ravindra M.

“…A highly efficient method for the synthesis of 2‐imino‐4‐(trifluoromethyl)thiazolidin‐4‐ol derivatives has been achieved by the one‐pot, three‐component…”
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Synthesis and evaluation of novel triazoles and mannich bases functionalized 1,4-dihydropyridine as angiotensin converting enzyme (ACE) inhibitors by Kumbhare, Ravindra M., Kosurkar, Umesh B., Bagul, Pankaj K., Kanwal, Abhinav, Appalanaidu, K., Dadmal, Tulshiram L., Banerjee, Sanjay Kumar

“…[Display omitted] A series of novel diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate embedded triazole and mannich bases were synthesized, and…”
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An Environmentally Benign Water Promoted Catalyst Free Highly Efficient, One-pot Synthesis of 2-Imino-4-thiazolidinone by Kosurkar, Umesh B., Dadmal, Tulshiram L., Kumbhare, Ravindra M., Sridhar, Balasubramanian

“…A practical and efficient protocol has been developed for the synthesis of 2‐imino‐4‐thiazolidinone through a unique one pot three‐component reaction of…”
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Novel Triazole linked 2-phenyl benzoxazole derivatives induce apoptosis by inhibiting miR-2, miR-13 and miR-14 function in Drosophila melanogaster by Mondal, Tanmoy, Lavanya, A. V. S., Mallick, Akash, Dadmala, Tulshiram L., Kumbhare, Ravindra M., Bhadra, Utpal, Bhadra, Manika Pal

“…Apoptosis is an important phenomenon in multi cellular organisms for maintaining tissue homeostasis and embryonic development. Defect in apoptosis leads to a…”
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Reduction in post-prandial hyperglycemic excursion through α-glucosidase inhibition by β-acetamido carbonyl compounds by Tiwari, Ashok K., Kumbhare, Ravindra M., Agawane, Sachin B., Ali, Amtul Z., Kumar, K. Vijay

“…A series of β-acetamido carbonyl compounds ( S 1– S 7) were prepared using Dakin-West reaction from different substituted aldehyde and acetophenone in the…”
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Trifluoromethanesulfonic acid promoted Dakin–West reaction: An efficient and convenient synthesis of β-acetamido ketones by KUMBHARE, RAVINDRA M, SRIDHAR, MADABHUSHI

“…Trifluoromethanesulfonic acid promoted efficient condensation of an aromatic aldehyde with an acetophenone and acetonitrile in the presence of acetylchloride…”
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Imidazo–benzothiazoles a potent microRNA modulator involved in cell proliferation by Pushpavalli, Sreerangam N.C.V.L., Janaki Ramaiah, M., Lavanya, A., Raksha Ganesh, A., Kumbhare, Ravindra M., Bhadra, Kaustav, Bhadra, Utpal, Pal-Bhadra, Manika

“…MicroRNAs are endogenously expressed tiny non-coding RNAs that control gene expression at the post-transcriptional level and regulate processes of cell growth,…”
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Magnesium fluoride catalyzed Knoevenagel reaction: An efficient synthesis of electrophilic alkenes by Kumbhare, Ravindra M., Sridhar, Madabhushi

“…An efficient Knoevenagel condensation under magnesium fluoride catalysis has been studied. A convenient method for synthesis of substituted olefins with…”
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Synthesis and Pharmacological Evaluation of Some Amide Functionalized 1H‐Benzo[d]imidazole‐2‐thiol Derivatives as Antimicrobial Agents by Singu, Padma S., Kanugala, Sirisha, Dhawale, Sachin A., Kumar, C. Ganesh, Kumbhare, Ravindra M.

“…A series of novel amide functionalized 1H‐benzo[d]imidazole‐2‐thiol derivatives 4 a‐o were prepared from substituted benzimidazole‐2‐thiol 1 a‐c. All the final…”
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Acid‐Catalyzed Four‐Component Tandem Double Cyclization: Access to Dihydroindolizino[8,7‐b]indoles by Shirsat, Prashishkumar K., Narasimhulu, Valipenta, Kumbhare, Ravindra M.

“…The novel one pot four‐component reaction for the construction of dihydroindolizino[8,7‐b]indoles and their derivatives have been developed from ninhydrine,…”
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Lewis Acid‐Catalyzed Substituted spiro 4‐thia‐1,2,6,9 tetraazaspiro[4.4]non‐2‐ene‐7,8‐diones via 1,3‐dipolar [3+2]cycloaddition by Lingareddy, Eeda, Nadagouda, Aishwarya, Sai, Lokavarapu, Pardha Saradhi, Todeti, Bansod, Sudhakar, Tangutur, Anjana Devi, Nanubolu, Jagadeesh Babu, Kumbhare, Ravindra M.

“…A series of substituted spiro 4‐thia‐1,2,6,9‐tetraazaspiro[4.4]non‐2‐ene‐7,8‐diones were synthesized with good yields through 1,3‐dipolar substituted…”
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Microwave accelerated Gewald reaction: synthesis of 2-aminothiophenes by Sridhar, Madabhushi, Rao, Rayankula Mallikarjuna, Baba, Nanduri H.K., Kumbhare, Ravindra M.

“…Microwave-promoted synthesis of 2-aminothiophenes by multicomponent reactions of a ketone with an active nitrile and elemental sulfur under KF-alumina…”
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