Search Results - "Kumaraswamy, H."

Nicotine promotes epithelial to mesenchymal transition and gemcitabine resistance via hENT1/RRM1 signalling in pancreatic cancer and chemosensitizing effects of Embelin-a naturally occurring benzoquinone by Prashanth N, Meghana P, Sandeep Kumar Jain R, Pooja S Rajaput, Satyanarayan N D, Raja Naika H, Kumaraswamy H M

“…Pancreatic cancer is lethal due to poor prognosis with 5-year survival rate lesser than 5 %. Gemcitabine is currently used to treat pancreatic cancer and…”
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Design and synthesis of new nicotinamide derivatives generated via Suzuki Miyaura coupling as potential anticancer hits targeting pancreatic cancer cell line MIA PaCa-2 by L, Vedavi, Rahman, Abdul, Rajaput, Pooja S, N, Nippu B, N, Prashanth, Kumaraswamy, H M, Mahadevan, K M, Satyanarayan, N D

“…•The 3-methoxyphenyl nicotinamide scaffolds were synthesised via Suzuki Miyaura coupling reaction.•The synthesised compounds were purified by…”
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Design, Synthesis and Anticancer Screening of Cu-Catalyzed SnAr Substituted Pyridine Bridged Ring Systems by B N, Nippu, Rahman, Abdul, Jain R, Sandeep Kumar, K S, Manjunatha, Kumaraswamy, H M, Mahadevan, K M, Satyanarayan, N D

“…•A series of new pyridine bridged ring systems were designed and synthesised.•CC (1-8) exhibits well-deserved in silico pharmacokinetic property.•CC (1-8)…”
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Synthesis and anticancer screening of some novel Pd-catalysed 3-methyl indole based analogues on Mia PaCa-2 cell line by Rahman, Abdul, N, Prashanth, N, Nippu B, Kumaraswamy, H M, Rajeshwara, A N, Satyanarayan, N D

“…•Novel Pd-Catalysed 3-methyl Indole based Analogues were synthesised via Suzuki-Miyaura and Buchwald Hartwig coupling.•The synthesized compounds were evaluated…”
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Exploration of Heterocyclic Molecules Inhibiting Angiogenesis via VEGF Pathway Targeting VEGFR-2: An In Silico Approach by Nippu, B. N., Kumaraswamy, H. M., Satyanarayan, N. D.

“…Cancer drug discovery is expensive, time-consuming, and hits the economy of any pharmaceutical industry. To minimize the time, a rational approach needs to be…”
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Novel 1,3-Indenedione-Based Azo Dyes: Synthesis, Characterization, Solvatochromic UV-Vis Absorption Study, and Biological Activity by Navaneethgowda, P. V., Bodke, Y. D., Manjunatha, B., Kumaraswamy, H. M., Meghana, P.

“…In this work, we reported the synthesis of novel indanedione-based azo dyes by a conventional diazo coupling reaction at 0–5°C. The synthesized dyes were…”
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Analysis of C-shape Slotted MSPA for 5G Sub Band Applications on Three Different Substrates by Nagaraju, P, Sachina, D H, Khan, Imran, Kumaraswamy, H V, Sudhindra, K R

“…A comparative analysis of a compact planar Square patch Microstrip Multiband antenna on three different substrates is proposed. The proposed design has a…”
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Tetrahydrobenzothiophene derivatives ameliorate Mia PaCa-2 cell progression and induces apoptosis via inhibiting EGFR2 tyrosine kinase signal by Rahman, Abdul, Sandeep Kumar Jain, R., Meghana, P., Nippu, B.N., Manjunatha, K.S., Rajaput, Pooja S., Kumaraswamy, H.M., Satyanarayan, N.D.

“…[Display omitted] •The thieophine-3-carbonitrile based compounds were designed and synthesized.•N-methyl piperazine based 5b was the most potent compound with…”
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Identification of potential inhibitors of ATM kinase: pharmacoinformatics and molecular dynamics simulation approach by Inchara Moodbagil, C., Mahmood, Riaz, Kumaraswamy, H.M., Chandramohan, Vivek, Dammalli, Manjunath, Sharath, R., Meghana, P., Sandeep Kumar Jain, R., Prashanth, N., Samartha, J.R.

“…Ataxia-Telangiectasia Mutated kinase (ATM kinase) is a well-established protein, maintains genome integrity and modulates cellular responses to DNA breakage…”
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Docking Based Screening of Potent Flavonoids as CHK2 Inhibitors from Genus Miliusa by Moodbagil, C. Inchara, Mahmood, Riaz, Jain, R. Sandeep Kumar, Meghana, P., Prashanth, N., Kumaraswamy, H. M., Sharath, R.

“…Annonaceae plants play significant role in ethanopharmacology due to their medicinal properties and phytochemically rich edible fruits. In that, flavonoids…”
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Potential role of embelin in the prevention of Freund’s adjuvant induced inflammation and ROS by Kumaraswamy, H. M., Krishna, V., Sharath, R., Satyanarayan, N. D., Meghana, P., Jain, R. Sandeep Kumar, Prashanth, N., Raja Naika, H.

“…Inflammation is a complex biological response involving immune cells to an infection creating injury to the normal tissues. The anti-inflammatory efficacy of…”
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Artabotrys odoratissimus Bark Extract Restores Ethanol Induced Redox Imbalance and Toxicity in Hepatocytes and In Vivo Model by P, Meghana, R, Sandeep Kumar Jain, N, Prashanth, J U, Santhosh Kumar, R, Sharath, N D, Satyanarayan, R, Rajesh, C, Inchara Moodbagil, H M, Kumaraswamy

“…Alcohol-induced oxidative stress is a key player in the development of liver diseases, and herbal alternatives are important means of ameliorating the…”
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Enhanced Performance Smart Antenna System using Levy Based Optimisation Algorithms for Mobile Communication by Fawad, Iffath, Kumaraswamy, H. V.

“…Optimisation in Antenna arrays is essential for enhancing various performance parameters by choosing optimum values for element positions, amplitude…”
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In vivo wound healing activity of the methanolic extract and its isolated constituent, gulonic acid gamma-lactone, obtained from Grewia tiliaefolia by Khadeer Ahamed, B Mohamed, Krishna, Venkatarangaiah, Malleshappa, Kumaraswamy H

“…Grewia tiliaefolia is a subtropical tree, its stem bark is widely used in traditional Indian medicines to heal chronic wounds, gastric ulcers, burning…”
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Effects of Microstrip Array Failures in a Smart Antenna System for 5G Mobile Communication by Fawad, Iffath, Kumaraswamy, H V

“…The main objective of this research is to investigate the effects of element failures in an Antenna Array. The proposed Uniform Linear Array (ULA) of…”
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Design of 28/38ghz Dual-Band Vertically Stacked Dipole Antenna for Millimeter-Wave 5G Communication by M, Deepak Patel N, Kumaraswamy, H V

“…The rapidly evolving landscape of wireless communication technologies has led to the emergence of the fifth-generation (5G) networks, aiming to provide high…”
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Energy Efficient 5G Networks: Techniques and Challenges by Inamdar, Mohammad Azharuddin, Kumaraswamy, H. V.

“…To address the requirements of ever growing demands of data, speed and voice from users, wireless communication plays a great role in the picture…”
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A Comprehensive Survey on Different Attacks on SDN and Approaches to Mitigate by Hatagundi, Mrityunjaya D, Kumaraswamy, H V

“…As the technologies leaning towards digitalization, there has been extensive scope for researches in the field of Software Defined Networking. The…”
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Binding and Oxidative Cleavage Studies of DNA by Mixed Ligand Co(III) and Ni(II) Complexes of Quinolo [3,2-b]Benzodiazapine and 1,10-Phenanthroline by Prabhakara, M. C., Naik, H. S. Bhojya, Krishna, V., Kumaraswamy, H. M.

“…Two mixed ligand complexes of the type [M(phen) 2 (qbdp)](PF 6 )n.xH 2 O where M = Co(III) and Ni(II), qbdp = quinolo[3,2-b] benzodiazepine and phen =…”
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Transmission of Video with Convolutional Coding in Cooperative Ad Hoc Networks by Padma, Usha, Kumaraswamy, H V, S, Ravishankar

“…In wireless networks, the value of cooperative communication cannot be over stated. It has attracted a lot of attention because of its capacity to successfully…”
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