Search Results - "Kumar Surapaneni, Sunil"

MicroRNA-941 regulates the proliferation of breast cancer cells by altering histone H3 Ser 10 phosphorylation by Surapaneni, Sunil Kumar, Bhat, Zahid Rafiq, Tikoo, Kulbhushan

“…Breast cancer including triple negative breast cancer (TNBC) represents an important clinical challenge, as these tumours often develop resistance to…”
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Role of Cannabidiol and Tetrahydrocannabivarin on Paclitaxel-induced neuropathic pain in rodents by Kumar Kalvala, Anil, Bagde, Arvind, Arthur, Peggy, Kumar Surapaneni, Sunil, Ramesh, Nimma, Nathani, Aakash, Singh, Mandip

“…•THCV, when combined with CBD, provides excellent neuroprotection against paclitaxel-induced peripheral neuropathy in mice.•THCV and CBD improve mitochondrial…”
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Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening by Gebeyehu, Aragaw, Surapaneni, Sunil Kumar, Huang, John, Mondal, Arindam, Wang, Vivian Ziwen, Haruna, Nana Fatima, Bagde, Arvind, Arthur, Peggy, Kutlehria, Shallu, Patel, Nil, Rishi, Arun K., Singh, Mandip

“…A series of stable and ready-to-use bioinks have been developed based on the xeno-free and tunable hydrogel (VitroGel) system. Cell laden scaffold fabrication…”
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Dysregulation of microRNAs and renin-angiotensin system in high salt diet-induced cardiac dysfunction in uninephrectomized rats by Amara, Venkateswara Rao, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan

“…Uninephrectomy is not associated with major adverse events in cardiovascular and renal functions of live kidney donors. The effect of high salt diet on the…”
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Combined Transcriptomic and Proteomic Profiling to Unravel Osimertinib, CARP-1 Functional Mimetic (CFM 4.17) Formulation and Telmisartan Combo Treatment in NSCLC Tumor Xenografts by Nimma, Ramesh, Kalvala, Anil Kumar, Patel, Nilkumar, Surapaneni, Sunil Kumar, Sun, Li, Singh, Rakesh, Nottingham, Ebony, Bagde, Arvind, Kommineni, Nagavendra, Arthur, Peggy, Nathani, Aakash, Meckes, David G, Singh, Mandip

“…The epidermal growth factor receptor (EGFR) is highly expressed in many non-small cell lung cancers (NSCLC), necessitating the use of EGFR-tyrosine kinase…”
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Synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,-12-dien-30-oate and erlotinib on erlotinib-resistant non-small cell lung cancer cells by Nottingham, Ebony, Mazzio, Elizabeth, Surapaneni, Sunil Kumar, Kutlehria, Shallu, Mondal, Arindam, Badisa, Ramesh, Safe, Stephen, Rishi, Arun K., Singh, Mandip

“…Non-small cell lung cancer (NSCLC) is often characterized by an underlying mutation in the epidermal growth factor receptor (EGFR), contributing to aggressive…”
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Isolation and characterization of phenolic compounds from Rhodiola imbricata, a Trans-Himalayan food crop having antioxidant and anticancer potential by Choudhary, Alka, Kumar, Raj, Srivastava, Ravi Bihari, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan, Singh, Inder Pal

“…•Extracts of roots of Rhodiola imbricata showed antioxidant and anticancer activities.•Nineteen compounds including four new compounds were obtained by…”
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Corrigendum to ‘Isolation and characterization of phenolic compounds from Rhodiola imbricata, a Trans-Himalayan food crop having antioxidant and anticancer potential’ by Choudhary, Alka, Kumar, Raj, Srivastava, Ravi Bihari, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan, Singh, Inder Pal

“…•Extracts of roots of Rhodiola imbricata showed antioxidant and anticancer activities.•Nineteen compounds including four new compounds were obtained by…”
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Gold nanoparticles-induced cytotoxicity in triple negative breast cancer involves different epigenetic alterations depending upon the surface charge by Surapaneni, Sunil Kumar, Bashir, Shafiya, Tikoo, Kulbhushan

“…Gold nanoparticles (AuNPs) are used enormously in different cancers but very little is known regarding their molecular mechanism and surface charge role in the…”
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Metformin attenuates cardiovascular and renal injury in uninephrectomized rats on DOCA-salt: Involvement of AMPK and miRNAs in cardioprotection by Amara, Venkateswara Rao, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan

“…Hypertension is associated with major cardiovascular (CV) and renal complications. The molecular intricacy by which hypertension leads to end organ damage is…”
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Cell death by gold nanoparticles in MDA‐MB‐231 cells involves different epigenetic alterations: role of surface charge by Surapaneni, Sunil Kumar, Bashir, Shafiya, Tikoo, Kulbhushan

“…Triple negative breast cancer represents an important clinical challenge, as these tumours do not respond to endocrinal therapy. Nanotechnology offers a…”
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Applications of Cannabinoids in Neuropathic Pain: An Updated Review by Arthur, Peggy, Kalvala, Anil Kumar, Surapaneni, Sunil Kumar, Singh, Mandip Sachdeva

“…Neuropathic pain is experienced due to injury to the nerves, underlying disease conditions or toxicity induced by chemotherapeutics. Multiple factors can…”
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Targeting lung cancer stem cells using combination of Tel and Docetaxel liposomes in 3D cultures and tumor xenografts by Arthur, Peggy, Patel, Nilkumar, Surapaneni, Sunil Kumar, Mondal, Arindam, Gebeyehu, Aragaw, Bagde, Arvind, Kutlehria, Shallu, Nottingham, Ebony, Singh, Mandip

“…Cancer stem cells (CSCs) accounts for recurrence and resistance to chemotherapy in various tumors. Efficacy of chemotherapeutic drugs is limited by tumor…”
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Folic acid functionalized long-circulating co-encapsulated docetaxel and curcumin solid lipid nanoparticles: In vitro evaluation, pharmacokinetic and biodistribution in rats by Pawar, Harish, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan, Singh, Charan, Burman, Rohani, Gill, Manjinder Singh, Suresh, Sarasija

“…The purpose of this study was to develop folic acid functionalized long-circulating co-encapsulated docetaxel (DTX) and curcumin (CRM) solid lipid…”
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The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice by Kalvala, Anil Kumar, Nimma, Ramesh, Bagde, Arvind, Surapaneni, Sunil Kumar, Patel, Nilkumar, Arthur, Peggy, Sun, Li, Singh, Rakesh, Kommineni, Nagavendra, Nathani, Aakash, Li, Yan, Singh, Mandip

“…The significant resistance to currently available chemotherapeutics makes treatment for TNBC a key clinical concern. Herein, we studied the anti-cancer…”
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Epigenetic regulation of protein tyrosine phosphatase PTPN12 in triple-negative breast cancer by Thummuri, Dinesh, Kumar, Sandeep, Surapaneni, Sunil Kumar, Tikoo, Kulbhushan

“…The present study showed that the expression of PTPN12 is epigenetically regulated. 5-Azacytidine (5-Azac), a DNA hypomethylating agent, significantly…”
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Cannabidiol loaded extracellular vesicles sensitize triple-negative breast cancer to doxorubicin in both in-vitro and in vivo models by Patel, Nilkumar, Kommineni, Nagavendra, Surapaneni, Sunil Kumar, Kalvala, Anil, Yaun, Xuegang, Gebeyehu, Aragaw, Arthur, Peggy, Duke, Leanne C., York, Sara B., Bagde, Arvind, Meckes, David G., Singh, Mandip

“…[Display omitted] •CBD EVs were successfully formulated for the first time with good entrapment efficiency and particle size.•Sustained release of CBD was…”
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Telmisartan Facilitates the Anticancer Effects of CARP-1 Functional Mimetic and Sorafenib in Rociletinib Resistant Non-small Cell Lung Cancer by Surapaneni, Sunil Kumar, Nottingham, Ebony, Mondal, Arindam, Patel, Nilkumar, Arthur, Peggy, Gebeyehu, Aragaw, Kalvala, Anil Kumar, Rishi, Arun K, Singh, Mandip

“…Tyrosine kinase inhibitors (TKIs) are used for the treatment of both wild type and mutant non-small cell lung cancer (NSCLC); however, acquired resistance is a…”
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Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: involvement of GADD45α, integrin-α5, -β5, -β1, and autophagy by Surapaneni, Sunil Kumar, Patel, Nilkumar, Sun, Li, Kommineni, Nagavendra, Kalvala, Anil Kumar, Gebeyehu, Aragaw, Arthur, Peggy, Duke, Leanne C., Nimma, Ramesh, G Meckes, David, Singh, Mandip

“…To date, promising therapy for triple negative breast cancer (TNBC) remains a serious concern clinically because of poor prognosis, resistance, and recurrence…”
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Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells by Miranda, Mariza Abreu, Marcato, Priscyla Daniely, Mondal, Arindam, Chowdhury, Nusrat, Gebeyehu, Aragaw, Surapaneni, Sunil Kumar, Bentley, Maria Vitória Lopes Badra, Amaral, Robson, Pan, Chong-Xian, Singh, Mandip

“…Glycoalkaloids have been widely demonstrated as potential anticancer agents. However, the chemosensitizing effect of these compounds with traditional…”
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