Search Results - "Kumar Dubey, Pramod"
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Efficient stepwise and one pot three-component synthesis of 2-amino-4-(2-oxo-2H-chromen-3-yl)thiophene-3-carbonitriles
Published in Tetrahedron letters (26-11-2014)“…[Display omitted] Environmentally benign conditions have been developed for the synthesis of 2-amino-4-(2-oxo-2H-chromen-3-yl)thiophene-3-carbonitriles (3)…”
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Synthesis, Biological Evaluation and In silico Studies of Compounds Based on Tryptophan‐Naproxen‐Triazole Hybrids
Published in ChemistrySelect (Weinheim) (11-12-2020)“…A hybrid of three different frameworks e. g. tryptophan, naproxen and triazole has been explored for the identification of potential antibacterial / anticancer…”
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Assembly of Benzothiazine and Triazole in a Single Molecular Entity: Synthesis of -Oxicam Derived Novel Molecules as Potential Antibacterial/ Anti-cancer Agents
Published in Mini reviews in medicinal chemistry (01-01-2020)“…Benzothiazine derivatives, because of their various biological activities have attracted particular attention in Med Chem and drug discovery efforts. The…”
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Enantiomeric separation of proton pump inhibitors on new generation chiral columns using LC and supercritical fluid chromatography
Published in Journal of separation science (01-09-2013)“…The enantioselectivity of proton pump inhibitors, namely, omeprazole, lansoprazole, rabeprazole, pantoprazole, tenatoprazole, and ilaprazole were studied using…”
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Sulfamic acid as a green, reusable catalyst for stepwise, tandem & one-pot solvent-free synthesis of pyrazole derivatives
Published in Chinese chemical letters (01-07-2017)“…Sulfamic acid(SA) is a bi-functional, cost-effective and reusable green catalyst for the synthesis of 4-(pyrazol-4-yl)methylenepyrazol-5(4H)-one derivatives by…”
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Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR
Published in Journal of pharmaceutical analysis (01-12-2017)“…One unknown impurity (Imp-II) during the analysis of laboratory batches of isoproterenol hydrochloride was detected in the level ranging from 0.04% to 0.12% by…”
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Thermal rearrangement of tert-butylsulfinamide
Published in Beilstein journal of organic chemistry (04-01-2011)“…tert-Butylsulfinamides are unstable above room temperature, and in chlorinated solvents they undergo rearrangement to form the more stable…”
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Regulatory and Patenting Aspects of Chiral Drugs
Published in Resonance (01-04-2024)“…Any chiral drug, when prepared using a chemical synthesis method, is usually obtained as a 50:50 racemic mixture of R and S enantiomers. Irrespective of…”
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The Rise, Fall and Re-emergence of DDT
Published in Resonance (01-08-2023)“…DDT does not occur naturally and is purely a laboratory-synthesized compound. After being in existence for over 60 years, its wide-spectrum insecticidal…”
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Chirality and Drug Activity
Published in Resonance (01-03-2023)“…Certain biological ‘receptors’ are known to generate disease conditions in the animal/human body. Small molecules, determined by the nature of their groups and…”
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One‐pot Synthesis of 3‐phenyl‐4‐pyrazolylmethylene‐isoxazol‐(5H)‐ones Catalyzed by Sodium Benzoate in Aqueous Media under the Influence of Ultrasound Waves: A Green Chemistry Approach
Published in Journal of heterocyclic chemistry (01-07-2017)“…A series of 4‐pyrazolylmethylene‐3‐phenylisoxazol‐5(4H)‐ones have been prepared from Knoevenagel condensation of pyrazole‐4‐carbaxaldehyde with isoxazolone…”
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Synthesis, biological evaluation, and docking study of a series of 1,4‐disubstituted 1,2,3‐triazole derivatives with an indole‐triazole‐peptide conjugate
Published in Journal of heterocyclic chemistry (01-08-2020)“…A series of new compounds containing an indole‐triazole‐peptide conjugate were designed as potential agents possessing the dual anti‐bacterial and anticancer…”
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1H-1,2,3-Triazolyl-substituted 1,3,4-oxadiazole derivatives containing structural features of ibuprofen/naproxen: Their synthesis and antibacterial evaluation
Published in Bioorganic & medicinal chemistry letters (01-11-2016)“…[Display omitted] 1H-1,2,3-Triazolyl-substituted 1,3,4-oxadiazole derivatives containing structural features of ibuprofen/naproxen were synthesized for the…”
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Synthesis of novel substituted 3-(4-((1H-benzo[d]imidazol-2-ylthio)methyl)-1-phenyl-1H-pyrazol-3-yl)-2H-chromen-2-ones: various approaches
Published in Research on chemical intermediates (01-07-2018)“…Considering benzimidazole as a privileged structure for developing probes of impressive pharmacological potentials, some new coumarin and pyrazole conjugates…”
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An efficient one-pot four-component Gewald reaction: Synthesis of substituted 2-aminothiophenes with coumarin–thiazole scaffolds under environmentally benign conditions
Published in Journal of sulfur chemistry (04-03-2019)“…An elegant and efficient method has been outlined for the synthesis of novel 5-amino-4-[4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl]-3-arylthiophene-2-carbonitriles…”
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A facile and expedient microwave-assisted solvent-free method for the synthesis of 2-amino-4-(2-oxo-2H-chromen-3-yl)nicotinonitriles
Published in Journal of the Iranian Chemical Society (01-07-2018)“…An efficient method for the synthesis of novel 2-amino-4-(2-oxo-2 H -chromen-3-yl)nicotinonitriles has been developed under solvent-free conditions using…”
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An Efficient One‐pot Three‐component Method for the Synthesis of 5‐Amino‐3‐(2‐oxo‐2H‐chromen‐3‐yl)‐7‐aryl‐7H‐thiazolo[3,2‐a]pyridine‐6,8‐dicarbonitriles
Published in Journal of heterocyclic chemistry (01-03-2019)“…A facile, convenient, and adequate method has been developed for the synthesis of novel…”
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Urea/thiourea: efficient, inexpensive and reusable catalysts for the synthesis of pyrazole derivatives with 2-iminothiazolidin-4-one and 2,4-thiazolidinediones under solvent-free conditions
Published in Molecular diversity (01-05-2017)“…An efficient and green synthesis of pyrazolyl-2,4-thiazolidinediones/pyrazolyl-2-iminothiazolidine-4-ones 7 ( a – j ) has been developed using urea/thiourea as…”
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Microwave-assisted efficient and convenient one-pot synthesis of novel 3-(4-aminothieno[2,3-d]pyrimidin-5-yl)coumarins under solvent-free conditions
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-07-2018)“…An efficient green synthesis of novel 3-(4-aminothieno[2,3- d ]pyrimidin-5-yl)coumarins has been developed. One-pot reaction of 3-acetylcoumarin,…”
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