Search Results - "Kumar, Swati A."

A combined microRNA-based targeted therapeutic approach to eradicate glioblastoma stem-like cells by Esposito, Carla L., Nuzzo, Silvia, Kumar, Swati A., Rienzo, Anna, Lawrence, Clare L., Pallini, Roberto, Shaw, Lisa, Alder, Jane E., Ricci-Vitiani, Lucia, Catuogno, Silvia, de Franciscis, Vittorio

“…A minor population of glioblastoma stem-like cells (GSCs) has been implicated in the relapse and resistance of glioblastoma to therapeutic treatments. Based on…”
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Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling by Okyar, Alper, Kumar, Swati A., Filipski, Elisabeth, Piccolo, Enza, Ozturk, Narin, Xandri-Monje, Helena, Pala, Zeliha, Abraham, Kristin, Gomes, Ana Rita Gato de Jesus, Orman, Mehmet N., Li, Xiao-Mei, Dallmann, Robert, Lévi, Francis, Ballesta, Annabelle

“…P-glycoprotein ( P-gp ) largely influences the pharmacokinetics (PK) and toxicities of xenobiotics in a patient-specific manner so that personalized drug…”
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Dose- and time-dependent tolerability and efficacy of organo-osmium complex FY26 and its tissue pharmacokinetics in hepatocarcinoma-bearing mice by Kumar, Swati A, Needham, Russell J, Abraham, Kristin, Bridgewater, Hannah E, Garbutt, Lauren A, Xandri-Monje, Helena, Dallmann, Robert, Perrier, Sebastien, Sadler, Peter J, Lévi, Francis

“…The organo-osmium complex [OsII(ɳ6-p-cym)(PhAzPy-NMe2)I]+ (FY26) exhibits promising in vitro antitumour activity against mouse hepatocarcinoma Hepa1-6 and…”
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