Search Results - "Kumar, Swaroop"
-
1
A novel fibrinolytic enzyme from marine Pseudomonas aeruginosa KU1 and its rapid in vivo thrombolysis with little haemolysis
Published in International journal of biological macromolecules (01-11-2020)“…A direct acting, extracellular, fibrinolytic enzyme, ~50 KDa from marine Pseudomonas aeruginosa KU1 (PEKU1), was purified. It was found to be a…”
Get full text
Journal Article -
2
Fibrinolytic Enzymes for Thrombolytic Therapy
Published in Advances in experimental medicine and biology (01-01-2019)“…Cardiovascular diseases are a group of disorders consisting importantly of coronary heart disease, peripheral arterial disease, cerebrovascular disease,…”
Get more information
Journal Article -
3
Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as antimalarials
Published in Bioorganic & medicinal chemistry (15-01-2009)“…A highly atom economic one pot synthesis of tetrahydropyridines was achieved by l-proline/TFA catalysed multicomponent reaction of β-keto-esters, aromatic…”
Get full text
Journal Article -
4
Implementation status of airborne infection control measures in primary and secondary public health facilities, Puducherry: A mixed-methods study
Published in Indian journal of community medicine (01-07-2023)“…Background: Poor ventilation in healthcare settings is a concern for airborne infections, particularly in light of the potential for coronavirus disease 2019…”
Get full text
Journal Article -
5
One pot efficient diversity oriented synthesis of polyfunctional styryl thiazolopyrimidines and their bio-evaluation as antimalarial and anti-HIV agents
Published in European journal of medicinal chemistry (01-09-2012)“…An efficient one pot synthesis of a series of pluripotent (E)-1-(3-methyl-5-aryl-7-styryl-5H-thiazolo[3,2-a]pyrimidin-6-yl)-3-arylprop-2-en-1-ones is reported…”
Get full text
Journal Article -
6
On-Chip Surface-Based Detection with Nanohole Arrays
Published in Analytical chemistry (Washington) (01-06-2007)“…A microfluidic device with integrated surface plasmon resonance (SPR) chemical and biological sensors based on arrays of nanoholes in gold films is…”
Get full text
Journal Article -
7
Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression
Published in Frontiers in oncology (14-09-2022)“…Mitochondrial SMAC/Diablo induces apoptosis by binding the inhibitor of apoptosis proteins (IAPs), thereby activating caspases and, subsequently, apoptosis…”
Get full text
Journal Article -
8
Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer's disease protects against mitochondrial dysfunction and mitigates brain pathology
Published in Translational neurodegeneration (28-12-2022)“…Alzheimer's disease (AD) exhibits mitochondrial dysfunctions associated with dysregulated metabolism, brain inflammation, synaptic loss, and neuronal cell…”
Get full text
Journal Article -
9
SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis
Published in Molecular oncology (01-11-2021)“…SMAC/Diablo, a pro‐apoptotic protein, yet it is overexpressed in several cancer types. We have described a noncanonical function for SMAC/Diablo as a regulator…”
Get full text
Journal Article -
10
Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study
Published in Journal of mass spectrometry. (01-12-2012)“…A sensitive and reliable high‐performance liquid chromatography–mass spectrometry (LC–MS/MS) was developed and validated for simultaneous quantification…”
Get full text
Journal Article -
11
Erosion wear performance of HVOF sprayed WC-10Co-4Cr + 2% TiO2 coating on SS-409 using slurry jet erosion tester
Published in Results in surfaces and interfaces (01-08-2024)“…Erosion is a phenomenon and is the primary cause of failure in numerous slurry transportation equipment such as pump impellers, pipeline fittings, etc. It…”
Get full text
Journal Article -
12
Assessment of Community Health Volunteers contribution and factors affecting their health care service delivery in selected urban wards of Puducherry – A mixed-methods operational research study
Published in Clinical epidemiology and global health (01-09-2022)“…Community participation gained its importance from the Alma Ata declaration in 1978. Improving coverage of these services depends on factors like availability,…”
Get full text
Journal Article -
13
Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks
Published in Biomolecules (Basel, Switzerland) (27-06-2022)“…Mesothelioma, an aggressive cancer with a poor prognosis, is linked to asbestos exposure. However, carbon nanotubes found in materials we are exposed to daily…”
Get full text
Journal Article -
14
Silencing the Mitochondrial Gatekeeper VDAC1 as a Potential Treatment for Bladder Cancer
Published in Cells (Basel, Switzerland) (01-04-2024)“…The strategy for treating bladder cancer (BC) depends on whether there is muscle invasion or not, with the latter mostly treated with intravesical therapy,…”
Get full text
Journal Article -
15
Contribution of community health care volunteers in facilitating mobilization for diabetes and hypertension screening among the general population residing in urban puducherry - An operational research study
Published in Journal of family medicine and primary care (01-02-2022)“…Introduction: Non-communicable diseases (NCDs) have contributed to almost half of the global disease burden. Many countries have experimented with Community…”
Get full text
Journal Article -
16
Naringin Attenuates the Diabetic Neuropathy in STZ-Induced Type 2 Diabetic Wistar Rats
Published in Life (Basel, Switzerland) (01-12-2022)“…The application of traditional medicines for the treatment of diseases, including diabetic neuropathy (DN), has received great attention. The aim of this study…”
Get full text
Journal Article -
17
Status of Substance use among Undergraduate Medical Students in a Selected Government Medical College in Puducherry - An Explanatory Mixed Method Study
Published in Indian journal of community medicine (01-04-2023)“…Studies have shown increase in health-risking behavior and a decline in health-promoting behavior among medical students during their stay in medical school…”
Get full text
Journal Article -
18
The VDAC1-based R-Tf-D-LP4 Peptide as a Potential Treatment for Diabetes Mellitus
Published in Cells (Basel, Switzerland) (19-02-2020)“…Diabetes mellitus is a metabolic disorder approaching epidemic proportions. Non-alcoholic fatty liver disease (NAFLD) regularly coexists with metabolic…”
Get full text
Journal Article -
19
Modification of 3D Printable Polymer Filaments for Radiation Shielding Applications
Published in Polymers (29-03-2023)“…There is a growing need to develop lead-free shielding materials that are safe, low weight, durable, environmentally friendly, chemically and mechanically…”
Get full text
Journal Article -
20
Malnutrition status and other common comorbidities among inmates of childcare homes in puducherry, India - An Analytical Cross-Sectional study
Published in Clinical epidemiology and global health (01-10-2021)“…Inmates of child care institutions constitutes a vulnerable group. It is important to monitor their health status. This study aimed at estimating the…”
Get full text
Journal Article