Search Results - "Kumar, Sushma"
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Host-gut microbiota derived secondary metabolite mediated regulation of Wnt/β-catenin pathway: a potential therapeutic axis in IBD and CRC
Published in Frontiers in oncology (2024)“…The intestinal tract encompasses one of the largest mucosal surfaces with a well-structured layer of intestinal epithelial cells supported by a network of…”
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Molnupiravir: Mechanism of action, clinical, and translational science
Published in Clinical and translational science (01-02-2024)“…Molnupiravir is an oral prodrug of the broadly active, antiviral ribonucleoside analog N‐hydroxycytidine (NHC). The primary circulating metabolite NHC is taken…”
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Stranded: A Mainstream VR Quantum Game For Novices
Published in 2022 IEEE International Conference on Quantum Computing and Engineering (QCE) (01-09-2022)“…In the larger picture of quantum technology, quantum education is mainly overlooked. We are developing an explorative puzzle-based VR quantum game, named…”
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Conference Proceeding -
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Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate is Non-inferior to Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-naive Adults With Human Immunodeficiency Virus-1 Infection: Week 48 Results of the DRIVE-AHEAD Trial
Published in Clinical infectious diseases (01-02-2019)“…In Human Immunodeficiency Virus-1 treatment-naive adults, a fixed combination of doravirine/lamivudine/tenofovir disoproxil fumarate demonstrated non-inferior…”
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Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (TDF) Versus Efavirenz/Emtricitabine/TDF in Treatment-naive Adults With Human Immunodeficiency Virus Type 1 Infection: Week 96 Results of the Randomized, Double-blind, Phase 3 DRIVE-AHEAD Noninferiority Trial
Published in Clinical infectious diseases (01-07-2021)“…Doravirine (DOR) is a nonnucleoside reverse-transcriptase inhibitor. In the phase 3 DRIVE-AHEAD trial in treatment-naive adults with human immunodeficiency…”
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Progesterone Induces Calcitonin Expression in the Baboon Endometrium Within the Window of Uterine Receptivity
Published in Biology of reproduction (01-04-2003)“…The mammalian uterus can accept a developing blastocyst for implantation only within a limited period of time, termed the receptive phase. Our previous studies…”
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Soft Colloidal Scaffolds Capable of Elastic Recovery after Large Compressive Strains
Published in Chemistry of materials (09-09-2014)“…Assemblies of inorganic or glassy particles are typically brittle and cannot sustain even moderate deformations. This restricts the use of such materials to…”
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Efficacy, safety and central nervous system effects after switch from efavirenz/tenofovir/emtricitabine to doravirine/tenofovir/lamivudine
Published in AIDS (London) (01-04-2021)“…Doravirine is an alternative treatment option for individuals who do not tolerate efavirenz. We assessed efficacy, safety, and CNS effects in adults with HIV-1…”
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Once-daily Doravirine in Human Immunodeficiency Virus Type 1–Infected, Antiretroviral-naive Adults: An Integrated Efficacy Analysis
Published in Clinical infectious diseases (17-03-2020)“…Abstract Background Doravirine (DOR) demonstrated noninferior efficacy to darunavir plus ritonavir (DRV+r) and efavirenz (EFV) in 2 ongoing phase 3 trials:…”
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Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development
Published in Journal of acquired immune deficiency syndromes (1999) (15-12-2020)“…BACKGROUND:Doravirine (DOR) is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) approved for the treatment of HIV-1 infection in patients with no…”
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Causal Beliefs, Acculturation and Mental Health Stigma Among Indian Immigrants in the United States
Published 01-01-2023“…Mental health stigma continues to remain a challenge for those individuals with mental illness and often is a barrier towards help-seeking and social…”
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Dissertation -
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Efficacy and Safety of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF) in Treatment-Naive Adults With HIV-1 and Transmitted Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations
Published in Journal of acquired immune deficiency syndromes (1999) (01-12-2019)“…Supplemental Digital Content is Available in the Text…”
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Journal Article -
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Once-daily Doravirine for Initial Treatment of Adults Living With Human Immunodeficiency Virus–1: An Integrated Safety Analysis
Published in Clinical infectious diseases (17-03-2020)“…Abstract Background A prespecified integrated safety analysis was conducted for 3 doravirine (DOR) double-blind trials (Phase IIb: P007 [NCT01632345]; Phase…”
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Switching to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF) Maintains HIV-1 Virologic Suppression Through 48 Weeks: Results of the DRIVE-SHIFT Trial
Published in Journal of acquired immune deficiency syndromes (1999) (01-08-2019)“…BACKGROUND:Doravirine is a novel, nonnucleoside reverse transcriptase inhibitor with demonstrated efficacy in treatment-naive adults with HIV-1. METHODS:In…”
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Preliminary studies on the effect of nanoparticle seed treatments on seed quality attributes and yield in chickpea
Published in Turkish journal of agriculture and forestry (01-01-2023)Get full text
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Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial
Published in The lancet HIV (01-05-2018)“…Doravirine is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) with a pharmacokinetic profile supporting once-daily dosing, and potent in-vitro…”
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Task sharing for managing common noncommunicable disease in a nurse led noncommunicable diseases clinic in peri-urban community of Chandigarh
Published in Indian journal of community medicine (01-10-2022)“…Background: Nurse led noncommunicable diseases (NCD) clinic may address the significant shortage of human resource for health for managing common NCDs. The…”
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Journal Article -
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Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 96-week results of a randomised, double-blind, non-inferiority, phase 3 trial
Published in The lancet HIV (01-01-2020)“…Doravirine is a novel, non-nucleoside reverse transcriptase inhibitor that has shown non-inferior efficacy to ritonavir-boosted darunavir, with a superior…”
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626. The Efficacy and Safety of Maintenance with Doravirine Plus Two NRTIs after Initial Suppression in Adults with HIV-1 in the DRIVE-FORWARD Clinical Trial: Results from the Study Extension through 192 Weeks
Published in Open forum infectious diseases (04-12-2021)“…Abstract Background DRIVE-FORWARD is a phase 3 trial with a completed double-blind period comparing doravirine (DOR) 100 mg with ritonavir-boosted darunavir…”
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Journal Article