Search Results - "Kumar, Sajeesh"

Current Advances in Immunomodulatory Biomaterials for Bone Regeneration by Lee, Jinkyu, Byun, Hayeon, Madhurakkat Perikamana, Sajeesh Kumar, Lee, Sangmin, Shin, Heungsoo

“…Biomaterials with suitable surface modification strategies are contributing significantly to the rapid development of the field of bone tissue engineering…”
Get full text

Materials from Mussel-Inspired Chemistry for Cell and Tissue Engineering Applications by Madhurakkat Perikamana, Sajeesh Kumar, Lee, Jinkyu, Lee, Yu Bin, Shin, Young Min, Lee, Esther J, Mikos, Antonios G, Shin, Heungsoo

“…Current advances in biomaterial fabrication techniques have broadened their application in different realms of biomedical engineering, spanning from drug…”
Get full text

Harnessing biochemical and structural cues for tenogenic differentiation of adipose derived stem cells (ADSCs) and development of an in vitro tissue interface mimicking tendon-bone insertion graft by Madhurakkat Perikamana, Sajeesh Kumar, Lee, Jinkyu, Ahmad, Taufiq, Kim, Eun Mi, Byun, Hayeon, Lee, Sangmin, Shin, Heungsoo

“…Tendon-bone interface tissue is extremely challenging to engineer because it exhibits complex gradients of structure, composition, biologics, and cellular…”
Get full text

Human adipose-derived stem cell spheroids incorporating platelet-derived growth factor (PDGF) and bio-minerals for vascularized bone tissue engineering by Lee, Jinkyu, Lee, Sangmin, Ahmad, Taufiq, Madhurakkat Perikamana, Sajeesh Kumar, Lee, Jinki, Kim, Eun Mi, Shin, Heungsoo

“…Stem cells with mineralized materials have been used for bone regeneration; however, engineering the complex vascularized structure of the natural bone remains…”
Get full text

Stem cell spheroids incorporating fibers coated with adenosine and polydopamine as a modular building blocks for bone tissue engineering by Ahmad, Taufiq, Byun, Hayeon, Lee, Jinkyu, Madhurakat Perikamana, Sajeesh Kumar, Shin, Young Min, Kim, Eun Mi, Shin, Heungsoo

“…Although stem cell spheroids offer great potential as functional building blocks for bottom-up bone tissue engineering, delivery of bioactive signals remain…”
Get full text

Effective Immobilization of BMP‑2 Mediated by Polydopamine Coating on Biodegradable Nanofibers for Enhanced in Vivo Bone Formation by Cho, Hyeong-jin, Madhurakkat Perikamana, Sajeesh Kumar, Lee, Ji-hye, Lee, Jinkyu, Lee, Kyung-Mi, Shin, Choongsoo S, Shin, Heungsoo

“…Although bone morphogenic proteins (BMPs) have been widely used for bone regeneration, the ideal delivery system with optimized dose and minimized side effects…”
Get full text

Molecularly Tailored Interface for Long‐Term Xenogeneic Cell Transplantation by Madhurakkat Perikamana, Sajeesh Kumar, Seale, Nailah, Hoque, Jiaul, Ryu, Ji Hyun, Kumar, Vardhman, Shih, Yuru Vernon, Varghese, Shyni

“…Encapsulation of therapeutic cells in a semipermeable device can mitigate the need for systemic immune suppression following cell transplantation by providing…”
Get full text

Hybrid-spheroids incorporating ECM like engineered fragmented fibers potentiate stem cell function by improved cell/cell and cell/ECM interactions by Ahmad, Taufiq, Lee, Jinkyu, Shin, Young Min, Shin, Hyeok Jun, Madhurakat Perikamana, Sajeesh Kumar, Park, Sun Hwa, Kim, Sung Won, Shin, Heungsoo

“…[Display omitted] Extracellular matrix (ECM) microenvironment is critical for the viability, stemness, and differentiation of stem cells. In this study, we…”
Get full text

Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration by Lee, Sangmin, Chang, Yun-Young, Lee, Jinkyu, Madhurakkat Perikamana, Sajeesh Kumar, Kim, Eun Mi, Jung, Yang-Hun, Yun, Jeong-Ho, Shin, Heungsoo

“…Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone-implant interface is still required…”
Get more information

Effects of Immobilized BMP‑2 and Nanofiber Morphology on In Vitro Osteogenic Differentiation of hMSCs and In Vivo Collagen Assembly of Regenerated Bone by Madhurakkat Perikamana, Sajeesh Kumar, Lee, Jinkyu, Ahmad, Taufiq, Jeong, Yonghoon, Kim, Do-Gyoon, Kim, Kyobum, Shin, Heungsoo

“…Engineering bone tissue is particularly challenging because of the distinctive structural features of bone within a complex biochemical environment. In the…”
Get full text

Oxidative Epigallocatechin Gallate Coating on Polymeric Substrates for Bone Tissue Regeneration by Madhurakkat Perikamana, Sajeesh Kumar, Lee, Sang Min, Lee, Jinkyu, Ahmad, Taufiq, Lee, Min Suk, Yang, Hee Seok, Shin, Heungsoo

“…Plant derived flavonoids have not been well explored in tissue engineering applications due to difficulties in efficient formulations with biomaterials for…”
Get full text

Effect of gradient biomineral concentrations on osteogenic and chondrogenic differentiation of adipose derived stem cells by Madhurakkat Perikamana, Sajeesh Kumar, Lee, Jinkyu, Park, So Yeon, Jung, Hyun Suk, Shin, Heungsoo

“…In this study, we prepared polydopamine-gelatin templated electrospun nanofibers, which were coated with precisely controlled amounts of biominerals in the…”
Get full text

Teledentistry: A Key Component in Access to Care by Daniel, Susan J., RDH, PhD, Kumar, Sajeesh, PhD

“…Abstract Teledentistry has the potential to address the oral care needs of those who have limited access to care. More research is needed to establish the…”
Get full text

Transforming Healthcare Cybersecurity from Reactive to Proactive: Current Status and Future Recommendations by Bhuyan, Soumitra Sudip, Kabir, Umar Y, Escareno, Jessica M., Ector, Kenya, Palakodeti, Sandeep, Wyant, David, Kumar, Sajeesh, Levy, Marian, Kedia, Satish, Dasgupta, Dipankar, Dobalian, Aram

“…The recent rise in cybersecurity breaches in healthcare organizations has put patients’ privacy at a higher risk of being exposed. Despite this threat and the…”
Get full text

Fabrication of in vitro 3D mineralized tissue by fusion of composite spheroids incorporating biomineral-coated nanofibers and human adipose-derived stem cells by Ahmad, Taufiq, Shin, Hyeok Jun, Lee, Jinkyu, Shin, Young Min, Perikamana, Sajeesh Kumar Madhurakat, Park, So Yeon, Jung, Hyun Suk, Shin, Heungsoo

“…[Display omitted] Development of a bone-like 3D microenvironment with stem cells has always been intriguing in bone tissue engineering. In this study, we…”
Get full text

Agglomeration of human dermal fibroblasts with ECM mimicking nano-fragments and their effects on proliferation and cell/ECM interactions by Ahmad, Taufiq, Shin, Young Min, Lee, Jinkyu, Shin, Hyeok Jun, Madhurakart Perikamana, Sajeesh Kumar, Shin, Heungsoo

“…Here, we engineered spheroids by using ECM mimicking nano-fragments (NFs) with fibroblasts and investigated their effect on proliferation and cell/ECM…”
Get full text

Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts by Ahmad, Taufiq, Byun, Hayeon, Shin, Hyeok Jun, Lee, Jinkyu, Madhurakkat Perikamana, Sajeesh Kumar, Kim, Eun Mi, Shin, Young Min, Shin, Heungsoo

“…Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing. However, the soluble delivery of adenosine has…”
Get more information

An In Vitro Microfluidic Alveolus Model to Study Lung Biomechanics by Kumar, Vardhman, Madhurakkat Perikamana, Sajeesh Kumar, Tata, Aleksandra, Hoque, Jiaul, Gilpin, Anna, Tata, Purushothama Rao, Varghese, Shyni

“…The gas exchange units of the lung, the alveoli, are mechanically active and undergo cyclic deformation during breathing. The epithelial cells that line the…”
Get full text

Effect of dual growth factor delivery using poly(lactic-co-glycolic acid) mesh on neovascularization in a mouse skin flap model by Lee, Min Suk, Kumar, Sajeesh, La, Wan-Geun, Oh, Jun Sung, Choi, Hae In, Lee, Soo-Hong, Shin, Heungsoo, Yang, Hee Seok

“…Skin flaps have the crucial issue that skin necrosis can occur due to tissue ischemia in the distal parts of flaps. To prevent tissue necrosis, skin flaps need…”
Get full text

The Use of DMAIC to Improve Quality Vaccination Recommendations in Chain Community Pharmacies by Patel, Urvi, Kumar, Sajeesh

“…Community pharmacies provide the convenience and ease of administrating vaccinations outside traditional settings. Vaccinations are health initiatives that…”
Get full text