Search Results - "Kumar, Penmetcha K. R."

Aptamer That Binds to the gD Protein of Herpes Simplex Virus 1 and Efficiently Inhibits Viral Entry by GOPINATH, Subash C. B, HAYASHI, Kyoko, KUMAR, Penmetcha K. R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Monitoring influenza hemagglutinin and glycan interactions using surface plasmon resonance by Suenaga, Emi, Mizuno, Hiroshi, Penmetcha, Kumar K.R.

“…► Hemagglutinin, HA, of influenza viruses binds to the host's cell surface complex glycans. ► Glycan binding preference of different HAs derived from sub-types…”
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Monitoring Biomolecular Interactions on a Digital Versatile Disk: A BioDVD Platform Technology by Gopinath, Subash C. B, Awazu, Koichi, Tominaga, Junji, Kumar, Penmetcha K. R

“…A spinning-disk biosensor utilizing optical interference of reflected light from a multilayered structure, consisting of dielectric, metal, and optical…”
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An RNA aptamer that distinguishes between closely related human influenza viruses and inhibits haemagglutinin-mediated membrane fusion by Gopinath, Subash C. B, Misono, Tomoko S, Kawasaki, Kazunori, Mizuno, Takafumi, Imai, Masaki, Odagiri, Takato, Kumar, Penmetcha K. R

“…1 Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Central 6, 1-1 Higashi, Tsukuba City,…”
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Biomolecular discrimination analyses by surface plasmon resonance by Gopinath, Subash C B, Kumar, Penmetcha K R

“…Biomolecular discrimination is one of the most important ways to discriminate closely related species. In the past, several biomolecules have been observed…”
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Topical application of polyethylenimine as a candidate for novel prophylactic therapeutics against genital herpes caused by herpes simplex virus by Hayashi, Kyoko, Onoue, Hiroki, Sasaki, Kohei, Lee, Jung-Bum, Kumar, Penmetcha K. R, Gopinath, Subash C. B, Maitani, Yoshie, Kai, Takashi, Hayashi, Toshimitsu

“…Herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) cause genital herpes, which can enhance the acquisition of human immunodeficiency virus. The development of…”
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Influence of Nanometric Holes on the Sensitivity of a Waveguide-Mode Sensor: Label-Free Nanosensor for the Analysis of RNA Aptamer−Ligand Interactions by Gopinath, Subash C. B, Awazu, Koichi, Fujimaki, Makoto, Sugimoto, Katsuaki, Ohki, Yoshimichi, Komatsubara, Tetsuro, Tominaga, Junji, Gupta, Kailash C, Kumar, Penmetcha K. R

“…Evanescent-field-coupled (EFC) waveguide-mode sensors can be used to detect nucleic acids or proteins from the changes in the local index of refraction upon…”
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Efficient RNA Aptamer against Human Influenza B Virus Hemagglutinin by Gopinath, Subash C.B, Sakamaki, Yuriko, Kawasaki, Kazunori, Kumar, Penmetcha K.R

“…Aptamers are known for their higher discriminating ability between closely related molecules and their requirement for only a small region for binding, as…”
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In Vitro-Transcribed Chrysanthemum stunt viroid RNA Is Infectious to Chrysanthemum and Other Plants by Matsushita, Yosuke, Penmetcha, Kumar K.R

“…Chrysanthemum stunt viroid (CSVd), a noncoding RNA, is known to cause chrysanthemum stunt disease, which affects the yield of flowers. To gain insights into…”
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RNA-Directed Amino Acid Coupling as a Model Reaction for Primitive Coded Translation by Harada, Kazuo, Aoyama, Shoko, Matsugami, Akimasa, Kumar, Penmetcha K. R., Katahira, Masato, Kato, Nobuo, Ohkanda, Junko

“…The stereochemical theory claims that primitive coded translation initially occurred in the RNA world by RNA‐directed amino acid coupling. In this study, we…”
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A potent anti-coagulant RNA aptamer inhibits blood coagulation by specifically blocking the extrinsic clotting pathway by Gopinath, Subash C B, Shikamoto, Yasuo, Mizuno, Hiroshi, Kumar, Penmetcha K R

“…A potent antidote-controlled aptamer, as an anticoagulant, has reportedly overcome the complications of acute bleeding by the administration of available…”
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An aptamer that binds efficiently to the hemagglutinins of highly pathogenic avian influenza viruses (H5N1 and H7N7) and inhibits hemagglutinin–glycan interactions by Suenaga, Emi, Kumar, Penmetcha K.R.

“…Highly pathogenic avian influenza (HPAI) H5 and H7 viruses have ravaged the poultry industry in numerous countries in Asia, Europe, Africa and the Middle East,…”
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Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand by KUMAREVEL, Thirumananseri, MIZUNO, Hiroshi, KUMAR, Penmetcha K. R

“…HutP regulates the expression of the hut structural genes of Bacillus subtilis by an anti-termination mechanism and requires two components, Mg2+ ions and…”
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Monitoring Intact Viruses Using Aptamers by Kumar, Penmetcha K R

“…Viral diagnosis and surveillance are necessary steps in containing the spread of viral diseases, and they help in the deployment of appropriate therapeutic…”
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Optimization of silica surface with nanosize holes for immobilization of biomolecules and analysis of their interactions by Gopinath, Subash C.B., Awazu, Koichi, Fujimaki, Makoto, Kumar, Penmetcha K.R., Komatsubara, Tetsuro

“…An evanescent-field-coupled waveguide-mode sensor of the Kretschmann configuration with a silica waveguide having nanoscale holes is an ideal tool for…”
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Systematic screening of viral entry inhibitors using surface plasmon resonance by Kumar, Penmetcha K.R.

“…Summary Viral binding and entry into host cells for various viruses have been studied extensively, yielding a detailed understanding of the overall viral entry…”
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Analysis of Compounds That Interfere with Herpes Simplex Virus–Host Receptor Interactions Using Surface Plasmon Resonance by Gopinath, Subash C. B, Hayashi, Kyoko, Lee, Jung-Bum, Kamori, Akiko, Dong, Cai-Xia, Hayashi, Toshimitsu, Kumar, Penmetcha K. R

“…The entry of herpes simplex virus into host cells involves a complex series of events that require concerted inputs from multiple HSV glycoproteins. Among…”
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A Sensitive Multilayered Structure Suitable for Biosensing on the BioDVD Platform by Gopinath, Subash C. B, Awazu, Koichi, Fons, Paul, Tominaga, Junji, Kumar, Penmetcha K. R

“…Several technologies are currently available for the analysis of biomolecular interactions with high sensitivity and efficiency. However, these instruments are…”
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Comparison of Influenza Virus Detection Methods by Takahara, Yusuke, Nakaya, Yuki, Yasuura, Masato, Ashiba, Hiroki, Kumar, Penmetcha K. R., Fujimaki, Makoto

“…In this study, we provide a cross-sectional comparison of existing influenza virus detection methods in terms of their sensitivity, sample volume required, and…”
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Expression of noncoding vault RNA in human malignant cells and its importance in mitoxantrone resistance by Gopinath, Subash C B, Wadhwa, Renu, Kumar, Penmetcha K R

“…Several noncoding RNAs do vital cellular functions, including gene regulation and cell differentiation. Previously, we reported that vault RNA (vRNA) has the…”
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