Search Results - "Kumar, Peeyush T"

Endothelial Cell Dysfunction and Injury in Subarachnoid Hemorrhage by Peeyush Kumar, T., McBride, Devin W., Dash, Pramod K., Matsumura, Kanako, Rubi, Alba, Blackburn, Spiros L.

“…In the brain, vascular endothelial cells conserve blood viscosity, control blood flow, and form the interface between central nervous system and circulating…”
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A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis by Ma, Shang, Santhosh, Devi, Kumar T., Peeyush, Huang, Zhen

“…Intimate communication between neural and vascular cells is critical for normal brain development and function. Germinal matrix (GM), a key primordium for the…”
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Microthrombi Correlates With Infarction and Delayed Neurological Deficits After Subarachnoid Hemorrhage in Mice by Dienel, Ari, Ammassam Veettil, Remya, Hong, Sung-Ha, Matsumura, Kanako, Kumar T., Peeyush, Yan, Yuanqing, Blackburn, Spiros L., Ballester, Leomar Y., Marrelli, Sean P., McCullough, Louise D., McBride, Devin W.

“…Background and Purpose: Delayed neurological deficits are a devastating consequence of subarachnoid hemorrhage (SAH), which affects about 30% of surviving…”
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Efficient Specification of Interneurons from Human Pluripotent Stem Cells by Dorsoventral and Rostrocaudal Modulation by Kim, Tae‐Gon, Yao, Ruiqin, Monnell, Travis, Cho, Jun‐Hyeong, Vasudevan, Anju, Koh, Alice, Peeyush, Kumar T., Moon, Minho, Datta, Debkanya, Bolshakov, Vadim Y., Kim, Kwang‐Soo, Chung, Sangmi

“…GABAergic interneurons regulate cortical neural networks by providing inhibitory inputs, and their malfunction, resulting in failure to intricately regulate…”
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Autonomous vascular networks synchronize GABA neuron migration in the embryonic forebrain by Won, Chungkil, Lin, Zhicheng, Kumar T., Peeyush, Li, Suyan, Ding, Lai, Elkhal, Abdallah, Szabó, Gábor, Vasudevan, Anju

“…Gamma-aminobutyric acid neurons, born in remote germinative zones in the ventral forebrain (telencephalon), migrate tangentially in two spatially distinct…”
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Neurobehavioral Deficits After Subarachnoid Hemorrhage in Mice: Sensitivity Analysis and Development of a New Composite Score by Matsumura, Kanako, Kumar, T Peeyush, Guddanti, Tejesh, Yan, Yuanqing, Blackburn, Spiros L, McBride, Devin W

“…Background Because of the failure of numerous clinical trials, various recommendations have been made to improve the usefulness of preclinical studies…”
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The Role of Thromboinflammation in Delayed Cerebral Ischemia after Subarachnoid Hemorrhage by McBride, Devin W, Blackburn, Spiros L, Peeyush, Kumar T, Matsumura, Kanako, Zhang, John H

“…Delayed cerebral ischemia (DCI) is a major determinant of patient outcome following aneurysmal subarachnoid hemorrhage. Although the exact mechanisms leading…”
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α7-Acetylcholine Receptor Signaling Reduces Neuroinflammation After Subarachnoid Hemorrhage in Mice by Dienel, Ari, Veettil, Remya A, Matsumura, Kanako, Savarraj, Jude P J, Choi, H Alex, Kumar T, Peeyush, Aronowski, Jaroslaw, Dash, Pramod, Blackburn, Spiros L, McBride, Devin W

“…Aneurysmal subarachnoid hemorrhage (aSAH) causes a robust inflammatory response which leads worse brain injury and poor outcomes. We investigated if…”
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Unique Contribution of Haptoglobin and Haptoglobin Genotype in Aneurysmal Subarachnoid Hemorrhage by Blackburn, Spiros L, Kumar, Peeyush T, McBride, Devin, Zeineddine, Hussein A, Leclerc, Jenna, Choi, H Alex, Dash, Pramod K, Grotta, James, Aronowski, Jaroslaw, Cardenas, Jessica C, Doré, Sylvain

“…Survivors of cerebral aneurysm rupture are at risk for significant morbidity and neurological deficits. Much of this is related to the effects of blood in the…”
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Isolation and culture of endothelial cells from the embryonic forebrain by Kumar T, Peeyush, Vasudevan, Anju

“…Embryonic brain endothelial cells can serve as an important tool in the study of angiogenesis and neurovascular development and interactions. The two vascular…”
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Confirming subarachnoid hemorrhage induction in the endovascular puncture mouse model by Dienel, Ari, Hong, Sung-Ha, Guzman, Jose, Kumar T., Peeyush, Blackburn, Spiros L., McBride, Devin W.

“…Experimental studies of subarachnoid hemorrhage (SAH) using the endovascular perforation model routinely use either cerebral blood flow (CBF) or intracranial…”
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Decreased GABA Receptor Binding in the Cerebral Cortex of Insulin Induced Hypoglycemic and Streptozotocin Induced Diabetic Rats by Antony, Sherin, Peeyush Kumar, T., Kuruvilla, Korah P., George, Naijil, Paulose, C. S.

“…Hypoglycemia is the major problem to blood glucose homeostasis in treatment of diabetes and is associated with severe irreversible consequences including…”
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Curcumin modulates dopaminergic receptor, CREB and phospholipase C gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats by Kumar, T Peeyush, Antony, Sherin, Gireesh, G, George, Naijil, Paulose, C S

“…Curcumin, an active principle component in rhizome of Curcuma longa, has proved its merit for diabetes through its anti-oxidative and anti-inflammatory…”
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Role of curcumin in the prevention of cholinergic mediated cortical dysfunctions in streptozotocin-induced diabetic rats by Peeyush Kumar, T., Antony, Sherin, Soman, Smijin, Kuruvilla, Korah P., George, Naijil, Paulose, C.S.

“…Diabetes exacerbates neuronal injury mediated through neurotransmitters deregulation in cerebral cortex. Our study analyzed the neuroprotective effect of…”
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Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats by Antony, Sherin, Peeyush Kumar, T, Mathew, Jobin, Anju, T R, Paulose, C S

“…Glucose homeostasis in humans is an important factor for the functioning of nervous system. Hypoglycemia and hyperglycemia is found to be associated with…”
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Effect of vitamin D3 in reducing metabolic and oxidative stress in the liver of streptozotocin-induced diabetic rats by George, Naijil, Peeyush Kumar, T., Antony, Sherin, Jayanarayanan, S., Paulose, C. S.

“…Diabetes mellitus is a growing health problem worldwide and is associated with severe liver complications. The aim of the present study is to analyse the…”
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Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage by Dienel, Ari, Kumar T, Peeyush, Blackburn, Spiros L, McBride, Devin W

“…Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of…”
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Behavioral deficit and decreased GABA receptor functional regulation in the cerebellum of epileptic rats: Effect of Bacopa monnieri and bacoside A by Mathew, Jobin, Peeyush Kumar, T, Khan, Reas S, Paulose, C.S

“…Abstract In the present study, the effects of Bacopa monnieri and its active component, bacoside A, on motor deficit and alterations of GABA receptor…”
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The effects of abnormalities of glucose homeostasis on the expression and binding of muscarinic receptors in cerebral cortex of rats by Sherin, Antony, Peeyush, Kumar T., Naijil, George, Nandhu, Mohan Sobhana, Jayanarayanan, Sadanandan, Jes, Paul, Paulose, Cheramadathikudiyil Skaria

“…Glucose homeostasis in humans is an important factor for the functioning of nervous system. Both hypo and hyperglycemia contributes to neuronal functional…”
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Effect of vitamin D 3 in reducing metabolic and oxidative stress in the liver of streptozotocin-induced diabetic rats by George, Naijil, Peeyush Kumar, T., Antony, Sherin, Jayanarayanan, S., Paulose, C. S.

“…Diabetes mellitus is a growing health problem worldwide and is associated with severe liver complications. The aim of the present study is to analyse the…”
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