Search Results - "Kumar, P. Rajender"

N-heterocyclic carbene-mediated hydroacylation-Sonogashira/Heck/Suzuki coupling in a single pot: a new cascade reaction by Sreenivasulu, M, Kumar, K Siva, Kumar, P Rajender, Chandrasekhar, K B, Pal, Manojit

“…A dually NHC-catalyzed reaction cascade comprising an initial hydroacylation of an activated ketone and subsequent Sonogashira/Heck/Suzuki coupling in the same…”
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Facile synthesis of substituted thiophenes via Pd/C-mediated sonogashira coupling in water by Raju, Sirisilla, Kumar, P. Rajender, Mukkanti, K., Annamalai, Pazhanimuthu, Pal, Manojit

“…The first successful Pd/C-mediated Sonogashira coupling of iodothiophene with terminal alkynes in water is described here. Pd/C-CuI-PPh 3 was found to be an…”
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A stability-indicating HPLC assay method for docetaxel by Rao, B. Mallikarjuna, Chakraborty, Arpita, Srinivasu, M.K., Devi, M. Lalitha, Kumar, P. Rajender, Chandrasekhar, K.B., Srinivasan, A.K., Prasad, A.S., Ramanatham, J.

“…A novel stability-indicating high-performance liquid chromatographic assay method was developed and validated for docetaxel in the presence of degradation…”
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Synthesis and biological evaluation of thiophene [3,2-b] pyrrole derivatives as potential anti-inflammatory agents by RAJENDER KUMAR, P, RAJU, S, SATISH GOUD, P, SAILAJA, M, SARMA, M. R, OM REDDY, G, PREM KUMAR, M, KRISHNA REDDY, V. V. R. M, SURESH, T, HEGDE, Pragathi

“…A series of thiophene [3,2-b] pyrrole derivatives were synthesized and evaluated their abilities to inhibit anti-inflammatory activity. In this series,…”
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A stability indicating LC method for Rivastigmine hydrogen tartrate by Rao, B. Mallikarjuna, Srinivasu, M.K., Kumar, K. Praveen, Bhradwaj, Neelu, Ravi, R., Mohakhud, Pradeep K., Reddy, G. Om, Kumar, P. Rajender

“…An isocratic, reversed-phase liquid chromatographic (RPLC) method was developed for the quantitative determination of Rivastigmine hydrogen tartrate, a…”
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Achiral bis-imine in combination with CoCl₂: A remarkable effect on enantioselectivity of lipase-mediated acetylation of racemic secondary alcohol by Arunkumar, K, Reddy, M Appi, Kumar, T Sravan, Kumar, B Vijaya, Chandrasekhar, K B, Kumar, P Rajender, Pal, Manojit

“…A bis-imine (prepared via a new FeCl₃-based method) in combination with CoCl₂ facilitated lipase-mediated acetylation of the (R)-isomer of a racemic benzylic…”
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A stability indicating LC method for zolmitriptan by Rao, B. Mallikarjuna, Srinivasu, M.K., Sridhar, G., Kumar, P. Rajender, Chandrasekhar, K.B., Islam, Aminul

“…A gradient, reversed-phase liquid chromatographic (RP-LC) assay method was developed for the quantitative determination of zolmitriptan, used to treat severe…”
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A validated stability indicating ion-pair RP-LC method for zoledronic acid by Rao, B. Mallikarjuna, Srinivasu, M.K., Rani, Ch. Prathima, kumar, S. Siva, Kumar, P. Rajender, Chandrasekhar, K.B., Veerender, M.

“…The present paper describes the development of a stability indicating high performance liquid chromatographic (HPLC) assay method for zoledronic acid in the…”
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A validated chiral LC method for the enantiomeric separation of Zolmitriptan key intermediate, ZTR-5 by Srinivasu, M.K., Rao, B. Mallikarjuna, Sridhar, G., Chandrasekhar, K.B., Kumar, P. Rajender

“…A new and accurate chiral liquid chromatographic method was described for the enantiomeric separation of ZTR-5 [(4 S)-4-(4-aminobenzyl)-2-oxazolidinone, (…”
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A validated chiral LC method for the determination of Zolmitriptan and its potential impurities by Srinivasu, M.K., Rao, B. Mallikarjuna, Sridhar, G., Kumar, P. Rajender, Chandrasekhar, K.B., Islam, Aminul

“…A new, accurate and reliable chiral HPLC method was developed for the determination of Zolmitriptan, (4 S)-4-[[3-[2-(dimethylamino)ethyl]-1 H-indol-5-yl]…”
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Isolation, synthesis and characterization of impurities in Celecoxib a cox-2 inhibitor by Satyanarayana, U, Rao, D.Sreenivas, Kumar, Y.Ravindra, Babu, J.Moses, Kumar, P.Rajender, Reddy, J.Tirupathi

“…During the impurity profile of Celecoxib, four polar impurities (impurity I, II, III and IV) and one non-polar impurity (impurity V) with respect to Celecoxib…”
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Catalysis by zeolite leading to the construction of thiazole ring: an improved synthesis of 4-alkynyl substituted thiazoles by Arunkumar, K., Naresh Kumar Reddy, D., Chandrasekhar, K.B., Rajender Kumar, P., Shiva Kumar, K., Pal, Manojit

“…Zeolite H-beta facilitated the reaction of α-chloro acetyl chloride with 1,2-bis-trimethyl silyl acetylene to give 1-chloro-4-(trimethylsilyl)but-3-yn-2-one…”
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1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride in combination with triethylamine: an improved catalytic system for hydroacylation/reduction of activated ketones by Sreenivasulu, M., Arun Kumar, K., Sateesh Reddy, K., Siva Kumar, K., Rajender Kumar, P., Chandrasekhar, K.B., Pal, Manojit

“…A rapid, economic, and high yielding methodology has been developed for hydroacylation/reduction of activated ketones by using…”
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Pd/C-catalyzed alkynylation of β-chloroacroleins by Bera, Rabin, Swamy, Nalivela Kumara, Dhananjaya, G., Moses Babu, J., Rajender Kumar, P., Mukkanti, K., Pal, Manojit

“…The first Pd/C-mediated Sonogashira coupling of β-chloroacroleins with terminal alkynes is described here. Pd/C–CuI–PPh 3 was found to be an efficient catalyst…”
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Impairment of metabolic capacities in copper and cadmium contaminated wild yellow perch ( Perca flavescens) by Couture, Patrice, Rajender Kumar, Puja

“…This study examined variations in resting oxygen consumption rate (ROCR), post-exercise oxygen consumption rate, relative scope for activity (RSA), liver and…”
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Revisiting the reaction of β-chloroacroleins with 2-aminophenol: a new observation by Bera, Rabin, Dhananjaya, G., Singh, Shambu Nath, Ramu, B., Kiran, Sai Uday, Kumar, P. Rajender, Mukkanti, K., Pal, Manojit

“…The reaction of β-chloroacrolein with 1 equiv of 2-aminophenol in DMF proceeds smoothly to afford 11-hydroxy derivative of chromenoquinoline in good yield…”
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Tandem versus single C–C bond forming reaction under palladium–copper catalysis: regioselective synthesis of α-pyrones fused with thiophene by Raju, Sirisilla, Batchu, Venkateswara Rao, Swamy, Nalivela Kumara, Dev, R. Vasu, Sreekanth, Bukkapattanam R., Babu, J. Moses, Vyas, K., Kumar, P. Rajender, Mukkanti, K., Annamalai, Pazhanimuthu, Pal, Manojit

“…We herein report a highly convenient protocol for rapid construction of α-pyrone fused with thiophene. This includes one-pot and regioselective synthesis of…”
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Achiral bis-imine in combination with CoCl 2 : A remarkable effect on enantioselectivity of lipase-mediated acetylation of racemic secondary alcohol by Arunkumar, K, Reddy, M Appi, Kumar, T Sravan, Kumar, B Vijaya, Chandrasekhar, K B, Kumar, P Rajender, Pal, Manojit

“…A bis-imine (prepared via a new FeCl 3 -based method) in combination with CoCl 2 facilitated lipase-mediated acetylation of the ( R )-isomer of a racemic…”
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Palladium-mediated synthesis of 5-substituted 4-alkynylthieno[2,3- c]pyran-7-ones by Raju, Sirisilla, Batchu, Venkateswara Rao, Swamy, Nalivela Kumara, Vasu Dev, R., Babu, J. Moses, Rajender Kumar, P., Mukkanti, K., Pal, Manojit

“…We describe here, the first palladium-mediated tandem C–C bond forming reaction between 3-iodothiophene-2-carboxylic acid and terminal alkynes to afford the…”
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Polymorphic Study of l-Arginine Salt of Ragaglitazar (DRF-2725) by Raju, S, Kumar, P. Rajender, Vyas, K, Rao, D. Srinivas, Sarma, M. R, Reddy, S. Vishnuvardhan, Nirmala, M, Reddy, G. Om

“…In the manufacturing process, during our attempts to get a suitable polymorph by reacting the aqueous solution of l-arginine with 3-[4-[2-(phenoxazin-10-yl)…”
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