Search Results - "Kumar, Kushal"
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1
Thiazole-containing compounds as therapeutic targets for cancer therapy
Published in European journal of medicinal chemistry (15-02-2020)“…In the last few decades, considerable progress has been made in anticancer agents development, and several new anticancer agents of natural and synthetic…”
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2
The Role of Forebody Topology on Aerodynamics and Aeroacoustics Characteristics of Squareback Vehicles using Computational Aeroacoustics (CAA)
Published in Flow, turbulence and combustion (01-04-2024)“…This study investigates the influence of forebody configuration on aerodynamic noise generation and radiation in standard squareback vehicles, employing a…”
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3
Photochemical Modulation of Biosafe Manganese Nanoparticles on Vigna radiata: A Detailed Molecular, Biochemical, and Biophysical Study
Published in Environmental science & technology (19-11-2013)“…Manganese (Mn) is an essential element for plants which intervenes mainly in photosynthesis. In this study we establish that manganese nanoparticles (MnNP)…”
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4
Greenhouse gas emission from rice fields: a review from Indian context
Published in Environmental science and pollution research international (01-06-2021)“…Agricultural soil acts as a source and sink of important greenhouse gases (GHGs) like methane (CH 4 ), nitrous oxide (N 2 O), and carbon dioxide (CO 2 ). Rice…”
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5
Therapeutic potential of GABAB receptor ligands in drug addiction, anxiety, depression and other CNS disorders
Published in Pharmacology, biochemistry and behavior (01-09-2013)“…Glutamate and γ-aminobutyric acid (GABA) are the major excitatory and inhibitory neurotransmitter systems, respectively in the central nervous system (CNS)…”
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6
Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation
Published in Nature communications (13-07-2017)“…The Bcl-2 proteins form a complex interaction network that controls mitochondrial permeabilization and apoptosis. The relative importance of different Bcl-2…”
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7
Benzothiazole Derivatives as Potential Anti-Infective Agents
Published in Current topics in medicinal chemistry (01-01-2017)“…Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents…”
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8
The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID
Published in The FEBS journal (01-03-2017)“…The BCL‐2 family members are key regulators of the intrinsic apoptotic pathway, which is defined by permeabilization of the mitochondrial outer membrane by…”
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9
Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria
Published in Journal of cell science (19-04-2018)“…Drp1, an 80-kDa mechanochemical GTPase of the dynamin superfamily, is required for mitochondrial division in mammals. Despite the role of Drp1 dysfunction in…”
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10
Citral enrichment in Lemongrass (Cymbopogon flexuosus) oil using spinning band equipped high vacuum distillation column and sensory evaluation of fractions
Published in Food chemistry advances (01-10-2023)“…•High vacuum fractional distillation of Lemongrass oil for citral enrich fraction.•Sensory analysis of the fractions for their organoleptic…”
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11
Incidence of microplastic contamination in fishes of the Ramsar Wetland, Loktak – The world's only floating lake from the Indian Himalayan region
Published in Journal of environmental management (01-05-2024)“…Microplastics are ubiquitous, and their widespread prevalence in the ecosphere has generated concerns about their potential effects on terrestrial and aquatic…”
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12
Methane emission associated with anatomical and morphophysiological characteristics of rice (Oryza sativa) plant
Published in Physiologia plantarum (01-10-2008)“…Plant-mediated transport is the primary route of methane (CH₄) emission from the reduced paddy field to the aboveground atmosphere. Experiments were conducted…”
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13
Understanding Pitfalls and Opportunities of Applying Heuristic Evaluation Methods to VR Training Systems: An Empirical Study
Published in International journal of human-computer interaction (02-05-2024)“…The usability of virtual reality (VR) training applications is crucial for their success, but examining the usability in the early development stages remains…”
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14
Estimation of slope stability using ensemble-based hybrid machine learning approaches
Published in Frontiers in materials (01-03-2024)“…Mining is one of the most daunting occupations gain the sector since it entails risk at any point in the operation. In its operation, the main focus is on…”
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15
Neuroprotective role of PDE4 and PDE5 inhibitors in 3-nitropropionic acid induced behavioral and biochemical toxicities in rats
Published in European journal of pharmacology (15-08-2013)“…Phosphodiesterase inhibitors have been reported to be beneficial in cognitive and motor disorders. In the present study, we have investigated the effects of RO…”
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16
Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge
Published in Bioinformatics (15-11-2013)“…After more than a decade since microarrays were used to predict phenotype of biological samples, real-life applications for disease screening and…”
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17
FK506 attenuates intracerebroventricular streptozotocin-induced neurotoxicity in rats
Published in Behavioural pharmacology (01-10-2013)“…Upregulation in calcineurin (CaN) signaling has been implicated in various neurodegenerative disorders. In the present study, we have investigated the effect…”
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18
Mutational probing of protein aggregates to design aggregation‐resistant proteins
Published in FEBS open bio (01-02-2016)“…Characterization of amorphous protein aggregates may offer insights into the process of aggregation. Eleven single amino acid mutants of lipase (LipA of…”
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19
Ondansetron induced fatal ventricular tachycardia
Published in Indian journal of pharmacology (01-07-2008)“…Ondansetron is a serotonin receptor antagonist used widely in the prophylaxis and treatment of postoperative nausea and vomiting (PONV) and vomiting associated…”
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20
Precision Agriculture Crop Recommendation System Using IoT and Machine Learning
Published in 2023 2nd International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies (ViTECoN) (05-05-2023)“…To define the term "smart farming," this work has used real-time applications over sensors to capture changes in the soil's and the atmosphere's climate. The…”
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