Search Results - "Kumar, Kandikattu Hemanth"

Neuroprotective effects of Cyperus rotundus on SIN-1 induced nitric oxide generation and protein nitration: Ameliorative effect against apoptosis mediated neuronal cell damage by Hemanth Kumar, Kandikattu, Tamatam, Anand, Pal, Ajay, Khanum, Farhath

“…► Cyperus rotundus rhizome extract (CRE) attenuated peroxynitrite induced neurotoxicity. ► CRE inhibited NO generation by downregulating i-NOS expression. ►…”
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Antioxidant, Biomolecule Oxidation Protective Activities of Nardostachys jatamansi DC and Its Phytochemical Analysis by RP-HPLC and GC-MS by Razack, Sakina, Kumar, Kandikattu Hemanth, Nallamuthu, Ilaiyaraja, Naika, Mahadeva, Khanum, Farhath

“…The study aimed at analyzing the metabolite profile of Nardostachys jatamansi using RP-HPLC, GC-MS and also its antioxidant, biomolecule protective and…”
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Phytochemical analysis and biological properties of Cyperus rotundus L by Hemanth Kumar, Kandikattu, Razack, Sakina, Nallamuthu, Ilaiyaraja, Khanum, Farhath

“…•Metabolites such as polyphenols, flavonoids and sesquiterpenes were identified by LC–ESI-MS/MS from Cyperus rotundus extract (CRE).•Radical induced depletion…”
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Role of IL‐18‐transformed CD274‐expressing eosinophils in promoting airway obstruction in experimental asthma by Mishra, Anil, Majid, Dewan, Kandikattu, Hemanth Kumar, Yadavalli, Chandra Sekhar, Upparahalli Venkateshaiah, Sathisha

“…Background IL‐5‐dependent residential and IL‐18‐transformed pathogenic eosinophils have been reported; however, the role of IL‐18‐transformed CD274‐expressing…”
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Eosinophils in the pathogenesis of pancreatic disorders by Manohar, Murli, Kandikattu, Hemanth Kumar, Upparahalli Venkateshaiah, Sathisha, Yadavalli, Chandra Sekhar, Mishra, Anil

“…Eosinophils comprise approximately 1–4% of total blood leukocytes that reside in the intestine, bone marrow, mammary gland, and adipose tissues to maintain…”
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Neuroprotective Effects of Hydroalcoholic Extract of Ocimum sanctum Against H2O2 Induced Neuronal Cell Damage in SH-SY5Y Cells via Its Antioxidative Defence Mechanism by Venuprasad, M. P., Hemanth Kumar, Kandikattu, Khanum, Farhath

“…Oxidative stress mediates the cell damage in several ailments including neurodegenerative conditions. Ocimum sanctum is widely used in Indian ayurvedic…”
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Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling by Erikson, John M., Valente, Anthony J., Mummidi, Srinivas, Kandikattu, Hemanth Kumar, DeMarco, Vincent G., Bender, Shawn B., Fay, William P., Siebenlist, Ulrich, Chandrasekar, Bysani

“…Re-establishing blood supply is the primary goal for reducing myocardial injury in subjects with ischemic heart disease. Paradoxically, reperfusion results in…”
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Development and Characterization of Novel Chronic Eosinophilic Inflammation- Mediated Murine Model of Malignant Pancreatitis by Kandikattu, Hemanth Kumar, Venkateshaiah, Sathisha Upparahalli, Yadavalli, Chandra Sekhar, Oruganti, Lokanatha, Mishra, Anil

“…Develop a novel murine models of malignant pancreatitis. Although patients with chronic pancreatitis are at a greater risk of developing pancreatic cancer,…”
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Phytochemical analysis and exercise enhancing effects of hydroalcoholic extract of Celastrus paniculatus Willd by Kumar Kandikattu, Hemanth, Venuprasad M.P., Pal, Ajay, Khanum, Farhath

“…[Display omitted] •The 70% ethanolic fraction of Celastrus paniculatus seed (CPSE) consist of sesquiterpenes and its esters as analyzed by GC–MS.•C…”
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Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice by Aroor, Annayya R, Habibi, Javad, Kandikattu, Hemanth Kumar, Garro-Kacher, Mona, Barron, Brady, Chen, Dongqing, Hayden, Melvin R, Whaley-Connell, Adam, Bender, Shawn B, Klein, Thomas, Padilla, Jaume, Sowers, James R, Chandrasekar, Bysani, DeMarco, Vincent G

“…Diastolic dysfunction (DD), a hallmark of obesity and primary defect in heart failure with preserved ejection fraction, is a predictor of future cardiovascular…”
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Phytochemical analysis of Ocimum gratissimum by LC-ESI–MS/MS and its antioxidant and anxiolytic effects by Venuprasad, M.P., Kumar Kandikattu, Hemanth, Razack, Sakina, Khanum, Farhath

“…Herbal extracts have been reported as alternate therapies for the treatment of psychiatric disorders and its associated oxidative stress. In the present study…”
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Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis by Yadavalli, Chandra Sekhar, Upparahalli Venkateshaiah, Sathisha, Kumar, Sandeep, Kandikattu, Hemanth Kumar, Oruganti, Lokanatha, Kathera, Chandra Sekhar, Mishra, Anil

“…The current report describes a stepwise mechanistic pathway of NLRP3/caspase1/IL-18-regulated immune responses operational in eosinophilic esophagitis (EoE)…”
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Chemical composition, antioxidant potential, macromolecule damage and neuroprotective activity of Convolvulus pluricaulis by Rachitha, P., Krupashree, K., Jayashree, G.V., Kandikattu, Hemanth Kumar, Amruta, Narayanappa, Gopalan, Natarajan, Rao, M.K., Khanum, Farhath

“…Herbal medicines are known to mitigate radical induced cell damage. Hence identification and scientific validation of herbal medicines contribute to better use…”
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Biochemical and Metabolomics on Rice Cultivars by Ranjitha, Hurugalavadi Puttaswamaiah, Gowda, Rame, Nethra, Nagarajappa, Amruta, Narayanappa, Kandikattu, Hemanth Kumar

“…Plant metabolites are important for both plant life and human nutrition. However, the genetic control of plant metabolome remains largely unknown. Here, we…”
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Bio-priming of rice seeds with novel bacterial strains, for management of seedborne Magnaporthe oryzae L by Narayanappa, Amruta, Prasanna Kumar M K, Kandikattu Hemanth Kumar, Sarika, G, Puneeth, M E, Ranjitha, H P, Vishwanath, K, Manjunatha, C, Pramesh, D, Mahesh, H B, Narayanaswamy, S

“…Rice blast disease caused by Magnaporthe oryzae is a seed borne which occurs in all rice growing regions of the country (India) causing yield losses up to 40%…”
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Exploring the Potentiality of Novel Rhizospheric Bacterial Strains against the Rice Blast Fungus Magnaporthe oryzae by Amruta, Narayanappa, Prasanna Kumar, M K, Puneeth, M E, Sarika, Gowdiperu, Kandikattu, Hemanth Kumar, Vishwanath, K, Narayanaswamy, Sonnappa

“…Rice blast caused by is a major disease. In the present study, we aimed to identify and evaluate the novel bacterial isolates from rice rhizosphere for…”
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IL-15 immunotherapy is a viable strategy for COVID-19 by Kandikattu, Hemanth Kumar, Venkateshaiah, Sathisha Upparahalli, Kumar, Sandeep, Mishra, Anil

“…•Epidemiology of COVID-19 and life cycle of SARS-CoV-2 in human cells was explored.•SARS-CoV-2-induced cell-mediated immunity plays a critical role in…”
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Tacrolimus ameliorates allergen, IL-5 and IL-13 induced eosinophilic esophagitis by Kandikattu, Hemanth Kumar, Mishra, Anil

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IL-18 overexpression promotes eosinophils-mediated peanut-induced intestinal allergy by Kandikattu, Hemanth Kumar, Mishra, Anil

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Cardiovascular Dysfunction in Intrauterine Growth Restriction by Amruta, Narayanappa, Kandikattu, Hemanth Kumar, Intapad, Suttira

“…Purpose of Review We highlight important new findings on cardiovascular dysfunction in intrauterine growth restriction. Recent Findings Intrauterine growth…”
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