Search Results - "Kumar, Justin P."

Building an ommatidium one cell at a time by Kumar, Justin P.

“…Since the discovery of a single white‐eyed male in a population of red eyed flies over 100 years ago (Morgan, 1910), the compound eye of the fruit fly,…”
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My what big eyes you have: How the Drosophila retina grows by Kumar, Justin P.

“…The compound eye of the fruit fly, Drosophila melanogaster, has for decades been used extensively to study a number of critical developmental processes…”
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A novel system for the launch of alphavirus RNA synthesis reveals a role for the Imd pathway in arthropod antiviral response by Avadhanula, Vasanthi, Weasner, Brandon P, Hardy, Gail G, Kumar, Justin P, Hardy, Richard W

“…Alphaviruses are RNA viruses transmitted between vertebrate hosts by arthropod vectors, primarily mosquitoes. How arthropods counteract alphaviruses or viruses…”
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Patterning of the Drosophila retina by the morphogenetic furrow by Warren, Jasmine, Kumar, Justin P

“…Pattern formation is the process by which cells within a homogeneous epithelial sheet acquire distinctive fates depending upon their relative spatial position…”
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Polycomb group (PcG) proteins and Pax6 cooperate to inhibit in vivo reprogramming of the developing Drosophila eye by Zhu, Jinjin, Ordway, Alison J, Weber, Lena, Buddika, Kasun, Kumar, Justin P

“…How different cells and tissues commit to and determine their fates has been a central question in developmental biology since the seminal embryological…”
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Eyeless/Pax6 initiates eye formation non-autonomously from the peripodial epithelium by Baker, Luke R, Weasner, Bonnie M, Nagel, Athena, Neuman, Sarah D, Bashirullah, Arash, Kumar, Justin P

“…The transcription factor Pax6 is considered the master control gene for eye formation because (1) it is present within the genomes and retina/lens of all…”
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Gene for eye placement comes into focus by Kumar, Justin P.

“…The Drosophila compound eye is an attractive system for unraveling how tissues are specified and patterned. Puli et al. recently demonstrated that eye size and…”
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Allocation of distinct organ fates from a precursor field requires a shift in expression and function of gene regulatory networks by Palliyil, Sneha, Zhu, Jinjin, Baker, Luke R, Neuman, Sarah D, Bashirullah, Arash, Kumar, Justin P

“…A common occurrence in metazoan development is the rise of multiple tissues/organs from a single uniform precursor field. One example is the anterior forebrain…”
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Retinal Expression of the Drosophila eyes absent Gene Is Controlled by Several Cooperatively Acting Cis-regulatory Elements by Weasner, Bonnie M, Weasner, Brandon P, Neuman, Sarah D, Bashirullah, Arash, Kumar, Justin P

“…The eyes absent (eya) gene of the fruit fly, Drosophila melanogaster, is a member of an evolutionarily conserved gene regulatory network that controls eye…”
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Creating the eye-antennal disc by fission by Kumar, Justin P

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Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster by Iyer, Janani, Wang, Qingyu, Le, Thanh, Pizzo, Lucilla, Grönke, Sebastian, Ambegaokar, Surendra S, Imai, Yuzuru, Srivastava, Ashutosh, Troisí, Beatriz Llamusí, Mardon, Graeme, Artero, Ruben, Jackson, George R, Isaacs, Adrian M, Partridge, Linda, Lu, Bingwei, Kumar, Justin P, Girirajan, Santhosh

“…About two-thirds of the vital genes in the Drosophila genome are involved in eye development, making the fly eye an excellent genetic system to study cellular…”
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The fly eye: Through the looking glass by Kumar, Justin P.

“…The developing eye‐antennal disc of Drosophila melanogaster has been studied for more than a century, and it has been used as a model system to study diverse…”
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Sine oculis, a member of the SIX family of transcription factors, directs eye formation by Weasner, Brandon, Salzer, Claire, Kumar, Justin P.

“…The initiation of eye formation in all seeing animals is controlled by a group of selector genes that together forms the retinal determination cascade. In…”
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Drosophila Dyrk2 plays a role in the development of the visual system by Luebbering, Nathan, Charlton-Perkins, Mark, Kumar, Justin P, Lochead, Pamela A, Rollmann, Stephanie M, Cook, Tiffany, Cleghon, Vaughn

“…The DYRKs (dual-specificity tyrosine phosphorylation-regulated kinases) are a conserved family of protein kinases that are associated with a number of…”
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Identification of retinal transformation hot spots in developing Drosophila epithelia by Salzer, Claire L, Kumar, Justin P

“…The retinal determination (RD) network is an evolutionarily conserved regulatory circuit that governs early events in the development of eyes throughout the…”
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A dissection of the teashirt and tiptop genes reveals a novel mechanism for regulating transcription factor activity by Datta, Rhea R., Weasner, Brandon P., Kumar, Justin P.

“…In the Drosophila eye the retinal determination (RD) network controls both tissue specification and cell proliferation. Mutations in network members result in…”
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The early history of the eye-antennal disc of Drosophila melanogaster by Weasner, Brandon P, Kumar, Justin P

“…Abstract A pair of eye-antennal imaginal discs give rise to nearly all external structures of the adult Drosophila head including the compound eyes, ocelli,…”
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Transcriptional activities of the Pax6 gene eyeless regulate tissue specificity of ectopic eye formation in Drosophila by Weasner, Bonnie M., Weasner, Brandon, DeYoung, Stephanie M., Michaels, Scott D., Kumar, Justin P.

“…Pax genes encode DNA binding proteins that play pivotal roles in the determination of complex tissues. Members of one subclass, Pax6, function as selector…”
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The timing of cell fate decisions is crucial for initiating pattern formation in the Drosophila eye by Weasner, Bonnie M, Kumar, Justin P

“…The eye-antennal disc of Drosophila is composed of three cell layers: a columnar epithelium called the disc proper (DP); an overlying sheet of squamous cells…”
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Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation by Zhu, Jinjin, Palliyil, Sneha, Ran, Chen, Kumar, Justin P.

“…Paired box 6 (Pax6) is considered to be the master control gene for eye development in all seeing animals studied so far. In vertebrates, it is required not…”
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