Search Results - "Kumar, Jetta Sandeep"

Recent advances in transition metal-catalyzed reactions of chloroquinoxalines: Applications in bioorganic chemistry by Sujeevan Reddy, Gangireddy, Sandeep Kumar, Jetta, Thirupataiah, B., Bhuktar, Harshavardhan, Shukla, Sharda, Pal, Manojit

“…An overview on various transition metal-catalyzed reactions of chloroquinoxalines and in vitro, in silico biological studies including SAR of the products…”
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Propargylamines in Pd/Cu-catalyzed tandem coupling-cyclization-N-deprotection in a single pot: Construction of N-unsubstituted vs N-sulfonyl indole ring by Sujeevan Reddy, Gangireddy, Sandeep Kumar, Jetta, Thirupataiah, B., Amirul Hossain, Kazi, Babu Nallapati, Suresh, Bhat Giliyaru, Varadaraj, Chandrashekhar Hariharapura, Raghu, Gautham Shenoy, G., Pal, Manojit

“…The construction of N-unsubstituted vs N-sulfonyl indole ring was studied using propargylamine as the terminal alkyne in the presence of Pd/Cu catalysts under…”
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CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors by Thirupataiah, B., Mounika, Guntipally, Sujeevan Reddy, Gangireddy, Sandeep Kumar, Jetta, Kapavarapu, Ravikumar, Medishetti, Raghavender, Mudgal, Jayesh, Mathew, Jessy E., Shenoy, Gautham G., Mallikarjuna Rao, C., Chatti, Kiranam, V. L. Parsa, Kishore, Pal, Manojit

“…[Display omitted] •New class of isoquinolin-1(2H)-ones were designed and explored as inhibitors of PDE4.•For the first time a CuCl2-catalyzed approach was…”
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Novel isatin-indole derivatives as potential inhibitors of chorismate mutase (CM): their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd-Cu catalysis by Reddy, Gangireddy Sujeevan, Hossain, Kazi Amirul, Kumar, Jetta Sandeep, Thirupataiah, B, Edwin, Rebecca Kristina, Giliyaru, Varadaraj Bhat, Chandrashekhar Hariharapura, Raghu, Shenoy, G. Gautham, Misra, Parimal, Pal, Manojit

“…A series of novel isatin-indole derivatives has been designed as potential inhibitors of chorismate mutase (CM) that is known to be present in bacteria, fungi…”
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PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor by Thirupataiah, B., Mounika, Guntipally, Reddy, Gangireddy Sujeevan, Kumar, Jetta Sandeep, Hossain, Kazi Amirul, Medishetti, Raghavender, Samarpita, Snigdha, Rasool, Mahaboobkhan, Mudgal, Jayesh, Mathew, Jessy E., Shenoy, Gautham G., Rao, C. Mallikarjuna, Chatti, Kiranam, Parsa, Kishore V.L., Pal, Manojit

“…While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor…”
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Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents by Kumar, Jetta Sandeep, Thirupataiah, B., Medishetti, Raghavender, Ray, Aramita, Bele, Shilpak Dilip, Hossain, Kazi Amirul, Reddy, Gangireddy Sujeevan, Edwin, Rebecca Kristina, Joseph, Alex, Kumar, Nitesh, Shenoy, Gautham G., Rao, C. Mallikarjuna, Pal, Manojit

“…A new class of 3-substituted isocoumarin/3-alkylidenephthalide based novel small molecules derived from rosuvastatin were designed and synthesized via the…”
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InCl3 mediated heteroarylation of indoles and their derivatization via C H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis by Sunke, Rajnikanth, Bankala, Ramudu, Thirupataiah, B., Ramarao, E.V.V. Shivaji, Kumar, Jetta Sandeep, Doss, Hari Maduri, Medishetti, Raghavender, Kulkarni, Pushkar, Kapavarapu, Ravi Kumar, Rasool, Mahaboobkhan, Mudgal, Jayesh, Mathew, Jessy E., Shenoy, Gautham G., Parsa, Kishore V.L., Pal, Manojit

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Sonochemical synthesis of rosuvastatin based novel 3-methyleneisoindolin-1-one derivatives as potential anticancer agents by Kumar, Jetta Sandeep, Reddy, Gangireddy Sujeevan, Medishetti, Raghavender, Ray, Aramita, Bele, Shilpak Dilip, Hossain, Kazi Amirul, Thirupataiah, B., Edwin, Rebecca Kristina, Behera, Parameswar, Joseph, Alex, Shenoy, Gautham G., Rao, C. Mallikarjuna, Pal, Manojit

“…•Rosuvastatin based novel 3-methyleneisoindolin-1-ones were explored as Akt1 inhibitors.•The Cu-catalyzed coupling-cyclization was used for their sonochemical…”
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Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT2CR by Sandeep Kumar, Jetta, Naimisha, Rapaka, Thirupataiah, B., Sujeevan Reddy, Gangireddy, Bung, Navneet, Roy, Arijit, Bulusu, Gopalakrishnan, Mishra, Ankita, Yadav, Prem N., Misra, Parimal, Pal, Manojit

“…[Display omitted] •3-(1-Hydroxycycloalkyl)isoquinolin-1-ones emerged as potential PAAM of 5-HT2CR.•These compounds and regioisomeric isoindolin-1-ones were…”
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Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonists by Reddy, Gangireddy Sujeevan, Kamaraj, Rajamanikkam, Hossain, Kazi Amirul, Kumar, Jetta Sandeep, Thirupataiah, B., Medishetti, Raghavender, Sushma Sri, N., Misra, Parimal, Pal, Manojit

“…• New chemical class • devoid of chiral center • simple/inexpensive synthesis • better fold changes/selectivity ratio over Lorcaserin • in vivo effects in…”
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Ultrasound assisted one-pot synthesis of rosuvastatin based novel azaindole derivatives via coupling–cyclization strategy under Pd/Cu-catalysis: Their evaluation as potential cytotoxic agents by Kumar, Jetta Sandeep, Reddy, Gangireddy Sujeevan, Medishetti, Raghavender, Amirul Hossain, Kazi, Thirupataiah, B., Edelli, Jhansi, Dilip Bele, Shilpak, Kristina Edwin, Rebecca, Joseph, Alex, Shenoy, Gautham G., Mallikarjuna Rao, C., Pal, Manojit

“…[Display omitted] •Rosuvastatin based azaindole framework was designed to identify cytotoxic agents.•Sonochemical synthesis of target compounds involved…”
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Fe(III)-catalyzed regioselective and faster synthesis of isocoumarins with 3-oxoalkyl moiety at C-4: Identification of new inhibitors of PDE4 by Thirupataiah, B., Bhuktar, Harshavardhan, Mounika, Guntipally, Reddy, Gangireddy Sujeevan, Kumar, Jetta Sandeep, Shukla, Sharda, Hossain, Kazi Amirul, Medishetti, Raghavender, Samarpita, Snigdha, Rasool, Mahaboobkhan, Jagadish, P.C., Shenoy, Gautham G., Parsa, Kishore V.L., Pal, Manojit

“…[Display omitted] •The inexpensive FeCl3 afforded regioselective and faster synthesis of isocoumarins.•Isocoumarins with 3-oxoalkyl moiety at C-4 showed potent…”
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Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT 2C R by Sandeep Kumar, Jetta, Naimisha, Rapaka, Thirupataiah, B, Sujeevan Reddy, Gangireddy, Bung, Navneet, Roy, Arijit, Bulusu, Gopalakrishnan, Mishra, Ankita, Yadav, Prem N, Misra, Parimal, Pal, Manojit

“…Efforts have been devoted for the discovery and development of positive allosteric modulators (PAMs) of 5-HT R because of their potential advantages over the…”
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Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor by Thirupataiah, B., Reddy, Gangireddy Sujeevan, Ghule, Shailendra S., Kumar, Jetta Sandeep, Mounika, Guntipally, Hossain, Kazi Amirul, Mudgal, Jayesh, Mathew, Jessy E., Shenoy, Gautham G., Parsa, Kishore V.L., Pal, Manojit

“…[Display omitted] •Anti-inflammatory activities of benzo[c]phenanthridines were explored.•These compounds were obtained via a new and multi-step…”
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InCl3 mediated heteroarylation of indoles and their derivatization via CH activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis by Sunke, Rajnikanth, Bankala, Ramudu, Thirupataiah, B., Ramarao, E.V.V. Shivaji, Kumar, Jetta Sandeep, Doss, Hari Maduri, Medishetti, Raghavender, Kulkarni, Pushkar, Kapavarapu, Ravi Kumar, Rasool, Mahaboobkhan, Mudgal, Jayesh, Mathew, Jessy E., Shenoy, Gautham G., Parsa, Kishore V.L., Pal, Manojit

“…A new class of PDE4 inhibitors were designed and synthesized via the InCl3 mediated heteroarylation of indoles and their further derivatization through the…”
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Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT 2C receptor agonists by Reddy, Gangireddy Sujeevan, Kamaraj, Rajamanikkam, Hossain, Kazi Amirul, Kumar, Jetta Sandeep, Thirupataiah, B, Medishetti, Raghavender, Sushma Sri, N, Misra, Parimal, Pal, Manojit

“…A series of indole based novel Schiff bases was designed as potential agonists of 5-HT receptor that was supported by docking studies in silico. These…”
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PdCl 2 -catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor by Thirupataiah, B, Mounika, Guntipally, Reddy, Gangireddy Sujeevan, Kumar, Jetta Sandeep, Hossain, Kazi Amirul, Medishetti, Raghavender, Samarpita, Snigdha, Rasool, Mahaboobkhan, Mudgal, Jayesh, Mathew, Jessy E, Shenoy, Gautham G, Rao, C Mallikarjuna, Chatti, Kiranam, Parsa, Kishore V L, Pal, Manojit

“…While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor…”
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Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl 3 -mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor by Thirupataiah, B, Reddy, Gangireddy Sujeevan, Ghule, Shailendra S, Kumar, Jetta Sandeep, Mounika, Guntipally, Hossain, Kazi Amirul, Mudgal, Jayesh, Mathew, Jessy E, Shenoy, Gautham G, Parsa, Kishore V L, Pal, Manojit

“…In spite of their various pharmacological properties the anti-inflammatory potential of benzo[c]phenanthridines remained underexplored. Thus, for the first…”
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InCl 3 mediated heteroarylation of indoles and their derivatization via CH activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis by Sunke, Rajnikanth, Bankala, Ramudu, Thirupataiah, B, Ramarao, E V V Shivaji, Kumar, Jetta Sandeep, Doss, Hari Maduri, Medishetti, Raghavender, Kulkarni, Pushkar, Kapavarapu, Ravi Kumar, Rasool, Mahaboobkhan, Mudgal, Jayesh, Mathew, Jessy E, Shenoy, Gautham G, Parsa, Kishore V L, Pal, Manojit

“…A new class of PDE4 inhibitors were designed and synthesized via the InCl mediated heteroarylation of indoles and their further derivatization through the…”
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