Search Results - "Kumar, JS Dileep"

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  1. 1

    In vivo Serotonin-Sensitive Binding of [11C]CUMI-101: A Serotonin 1A Receptor Agonist Positron Emission Tomography Radiotracer by Milak, Matthew S, Severance, Alin J, Prabhakaran, Jaya, Kumar, JS Dileep, Majo, Vattoly J, Ogden, R Todd, Mann, J John, Parsey, Ramin V

    “…Positron emission tomography studies of 5-hydroxytryptamine (5-HT)1A receptors have hitherto been limited to antagonist radiotracers. Antagonists do not…”
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    Journal Article
  2. 2

    Modeling Considerations for In Vivo Quantification of the Dopamine Transporter using [11C]PE2I and Positron Emission Tomography by DeLorenzo, Christine, Kumar, JS Dileep, Zanderigo, Francesca, Mann, J John, Parsey, Ramin V

    “…The dopamine transporter (DAT) is an important imaging target as changes in DAT have been implicated in a variety of neurologic and psychiatric disorders and…”
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    Journal Article
  3. 3

    PET tracers for serotonin receptors and their applications by Kumar, J S Dileep, Mann, J John

    “…Serotonin receptors (5-HTRs) are implicated in the pathophysiology of a variety of neuropsychiatric and neurodegenerative disorders and are also targets for…”
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    Journal Article
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    Binding saturation with the serotonin 1A receptor agonist [H-3]CUMI-101 and the antagonist [H-3]MPPF, in awake rats by Palner, Mikael, Underwood, Mark D., Kumar, Dileep J.S., Arango, Victoria, Knudsen, Gitte M., Mann, J. John, Parsey, Ramin V.

    Published in NeuroImage (Orlando, Fla.) (01-08-2010)
    “…An agonist binds to two conformational states of G-protein coupled receptor, the coupled state with high affinity and the uncoupled state with low affinity,…”
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    In Vivo Quantification of Human Serotonin 1A Receptor Using ^sup 11^C-CUMI-101, an Agonist PET Radiotracer by Milak, Matthew S, DeLorenzo, Christine, Zanderigo, Francesca, Prabhakaran, Jaya, Kumar, JS Dileep, Majo, Vattoly J, Mann, J John, Parsey, Ramin V

    Published in The Journal of nuclear medicine (1978) (01-12-2010)
    “…The serotonin (5-hydroxytryptamine, or 5-HT) type 1A receptor (5-HT^sub 1A^R) is implicated in the pathophysiology of numerous neuropsychiatric disorders. We…”
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    Journal Article
  9. 9

    In vivo variation in metabotropic glutamate receptor subtype 5 binding using [11C]ABP688 by DeLorenzo, Christine, Kumar, J.S. Dileep, Tauscher, Johannes, Mann, J. John, Parsey, Ramin V.

    Published in NeuroImage (Orlando, Fla.) (01-08-2010)
    “…An unconstrained two-tissue compartment modeling method was used to model these TACs and obtain estimates of VT, the ratio of the regional concentration of…”
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    Journal Article