Search Results - "Kumar, JS Dileep"
-
1
In vivo Serotonin-Sensitive Binding of [11C]CUMI-101: A Serotonin 1A Receptor Agonist Positron Emission Tomography Radiotracer
Published in Journal of cerebral blood flow and metabolism (01-01-2011)“…Positron emission tomography studies of 5-hydroxytryptamine (5-HT)1A receptors have hitherto been limited to antagonist radiotracers. Antagonists do not…”
Get full text
Journal Article -
2
Modeling Considerations for In Vivo Quantification of the Dopamine Transporter using [11C]PE2I and Positron Emission Tomography
Published in Journal of cerebral blood flow and metabolism (01-07-2009)“…The dopamine transporter (DAT) is an important imaging target as changes in DAT have been implicated in a variety of neurologic and psychiatric disorders and…”
Get full text
Journal Article -
3
PET tracers for serotonin receptors and their applications
Published in Central nervous system agents in medicinal chemistry (01-09-2014)“…Serotonin receptors (5-HTRs) are implicated in the pathophysiology of a variety of neuropsychiatric and neurodegenerative disorders and are also targets for…”
Get more information
Journal Article -
4
Pittsburgh Compound B (11C-PIB) and Fluorodeoxyglucose (18 F-FDG) PET in Patients With Alzheimer Disease, Mild Cognitive Impairment, and Healthy Controls
Published in Journal of geriatric psychiatry and neurology (01-09-2010)“…Amyloid load in the brain using Pittsburgh compound B (11C-PIB) positron emission tomography (PET) and cerebral glucose metabolism using fluorodeoxyglucose…”
Get full text
Journal Article -
5
Binding saturation with the serotonin 1A receptor agonist [H-3]CUMI-101 and the antagonist [H-3]MPPF, in awake rats
Published in NeuroImage (Orlando, Fla.) (01-08-2010)“…An agonist binds to two conformational states of G-protein coupled receptor, the coupled state with high affinity and the uncoupled state with low affinity,…”
Get full text
Journal Article -
6
P3‐087: IN VIVO EVALUATIONS OF MICROTUBULE‐BASED PET RADIOTRACER, [11C]MPC‐6827 IN MURINE MODELS OF ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2019)Get full text
Journal Article -
7
IN VIVO EVALUATIONS OF MICROTUBULE-BASED PET RADIOTRACER, [11C]MPC-6827 IN MURINE MODELS OF ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2019)Get full text
Journal Article -
8
In Vivo Quantification of Human Serotonin 1A Receptor Using ^sup 11^C-CUMI-101, an Agonist PET Radiotracer
Published in The Journal of nuclear medicine (1978) (01-12-2010)“…The serotonin (5-hydroxytryptamine, or 5-HT) type 1A receptor (5-HT^sub 1A^R) is implicated in the pathophysiology of numerous neuropsychiatric disorders. We…”
Get full text
Journal Article -
9
In vivo variation in metabotropic glutamate receptor subtype 5 binding using [11C]ABP688
Published in NeuroImage (Orlando, Fla.) (01-08-2010)“…An unconstrained two-tissue compartment modeling method was used to model these TACs and obtain estimates of VT, the ratio of the regional concentration of…”
Get full text
Journal Article