Search Results - "Kumar, Honnaiah Vijay"
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Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: Preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core
Published in Bioorganic & medicinal chemistry letters (15-12-2012)“…The study has been achieved the efficient synthesis of vanillin derived piperidin-4-one oxime esters (5a–m) via four step reaction involved Mannich reaction of…”
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Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: As a new class of potent antioxidants and antimicrobials-A novel accost to amend biocompatibility
Published in Bioorganic & medicinal chemistry letters (15-07-2012)“…In search for a new antioxidant and antimicrobial agent with improved potency, we synthesized a series of benzofuran based 1,3,5-substituted pyrazole analogues…”
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Isolation and characterization of biofumigant from leaves of Lantana camara for control of stored grain insect pests
Published in Industrial crops and products (01-11-2013)“…•Isolation and characterization of biofumigant molecule named as Coumaran from the leaves of a weed plant.•This molecule (Coumaran) is toxic to stored grain…”
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Functionalized 3-(benzofuran-2-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole scaffolds: A new class of antimicrobials and antioxidants
Published in Arabian journal of chemistry (01-05-2017)“…A new class of functionalized 3-(benzofuran-2-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole scaffolds (4a–q) was synthesized by a four step reaction in good…”
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5
The reaction of aspirin with base
Published in Tetrahedron letters (13-07-2011)“…Deprotonation of aspirin leads to a mixture of mixed anhydride (II) and cyclic orthoacetate (III), as indicated by IR, UV and NMR. Aspirin anion(I) itself…”
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N′-Acylation of (3,2′)-indole dimers
Published in Tetrahedron letters (18-05-2016)“…[Display omitted] •Synthesis of N′-acylated (3,2′)-indole dimers.•Biologically active crotonoyl, sorboyl, and cinnamoyl amides.•Ketene-derived…”
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Synthesis of thiazole-based substituted piperidinone oximes: Profiling of antioxidant and antimicrobial activity
Published in Russian journal of bioorganic chemistry (01-03-2017)“…The synthesis of novel thiazole-based piperidinone oximes and screening of their antioxidant and antimicrobial activity are described. The obtained results…”
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Fe-Catalyzed Domino Intramolecular Nucleophilic Substitution of 4‑Hydroxychromen-2-one and Pyran-2-one/Ring Opening of Activated Arene: An Easy Access to 2,3-Disubstituted Furo[3,2,‑c]coumarins and Furo[3,2,‑c]pyran-4-ones via Nonsymmetric Triarylmethanes
Published in Organic letters (06-03-2020)“…A one-pot synthesis of functionalized 2,3-disubstituted furo[3,2,-c]coumarins and furo[3,2,-c]pyran-4-ones under hydrated ferric sulfate catalysis was…”
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An Expeditious Coumarin Synthesis via a "Pseudocycloaddition" Between Salicylaldehydes and Ketene
Published in Synthetic communications (17-01-2015)“…A variety of salicylaldehydes effected tandem nucleophilic addition onto ketene, leading to corresponding coumarins in good yields under mild conditions. This…”
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5-Formylcytosine mediated DNA-peptide cross-link induces predominantly semi-targeted mutations in both Escherichia coli and human cells
Published in The Journal of biological chemistry (01-04-2024)“…Histone proteins can become trapped on DNA in the presence of 5-formylcytosine (5fC) to form toxic DNA-protein conjugates. Their repair may involve proteolytic…”
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Hydrated ferric sulfate-catalyzed reactions of indole with aldehydes, ketones, cyclic ketones, and chromanones: Synthesis of bisindoles and trisindoles
Published in Tetrahedron (06-07-2017)“…Hydrated ferric sulfate [Fe2(SO4)3·xH2O] has been found to be an efficient catalyst for condensation of bisindoles or trisindoles with aliphatic or aryl…”
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Diels–Alder/Ene Reactivities of 2‑(1′-Cycloalkenyl)thiophenes and 2‑(1′-Cycloalkenyl)benzo[b]thiophenes with N‑Phenylmaleimides: Role of Cycloalkene Ring Size on Benzothiophene and Dibenzothiophene Product Distributions
Published in Journal of organic chemistry (17-04-2020)“…Scaffolds of thiophene and benzothiophene are the important class of bioactive compounds found abundant in nature. The Diels–Alder reactions of…”
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Diels-Alder reactions of fused 5-, 6- and 7-membered ring 2-vinylindoles: Synthesis of annulated tetrahydrocarbazoles
Published in Tetrahedron (02-11-2017)“…Scaffolds of tetrahydrocarbazoles are an important class of biologically active compounds found abundant in nature. In the present investigation,…”
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Synthesis of Novel Benzofuran-Gathered C-2,4,6-substituted Pyrimidine Derivatives Conjugated by Sulfonyl Chlorides: Orally Bioavailable, Selective, Effective Antioxidants and Antimicrobials Drug Candidates
Published in Journal of heterocyclic chemistry (01-09-2015)“…In the present study, we have made an effort to develop the novel synthetic antioxidants and antimicrobials with improved potency. The novel…”
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Synthesis of novel indole based scaffolds holding pyrazole ring as anti-inflammatory and antioxidant agents
Published in Journal of pharmacy research (01-07-2013)Get full text
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Novel 2,6-bis(4-methoxyphenyl)-1-methylpiperidin-4-one oxime esters: synthesis and a new insight into their antioxidant and antimicrobial potential
Published in Medicinal chemistry research (01-04-2014)“…A simple and efficient protocol for the synthesis of novel 2,6-bis(4-methoxyphenyl)-1-methylpiperidin-4-one oxime esters 4(a–q) is described. Initially, p…”
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