Search Results - "Kumar, H. S. Arun"

Network Proteins of Human Sortilin1, Its Expression and Targetability Using Lycopene by Kumar, Arun H S

“…Sortilin1 (SORT1) is a ubiquitously expressed transporter involved in sorting or clearing proteins and is pathologically linked to tissue fibrosis and…”
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Exopolysaccharide-producing probiotic Lactobacilli reduce serum cholesterol and modify enteric microbiota in ApoE-deficient mice by London, Lis E E, Kumar, Arun H S, Wall, Rebecca, Casey, Pat G, O'Sullivan, Orla, Shanahan, Fergus, Hill, Colin, Cotter, Paul D, Fitzgerald, Gerald F, Ross, R Paul, Caplice, Noel M, Stanton, Catherine

“…Probiotic bacteria have been associated with a reduction in cardiovascular disease risk, a leading cause of death and disability. The aim of this study was to…”
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Bone Marrow‐Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy by Gleeson, Birgitta M., Martin, Kenneth, Ali, Mohammed T., Kumar, Arun H. S., Pillai, M. Gopala‐Krishnan, Kumar, Sujith P. G., O'Sullivan, John F., Whelan, Derek, Stocca, Alessia, Khider, Wisam, Barry, Frank P., O'Brien, Timothy, Caplice, Noel M.

“…Mesenchymal stem cells (MSCs) are currently under investigation as tools to preserve cardiac structure and function following acute myocardial infarction…”
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Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose by Taye, Ashraf, Saad, Adel H., Kumar, Arun HS, Morawietz, Henning

“…Hyperglycemia-induced generation of reactive oxygen species contributes to the development of proatherogenic changes and vasculopathy in diabetes. NADPH…”
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Reduced cGMP Signaling Associated with Neointimal Proliferation and Vascular Dysfunction in Late-Stage Atherosclerosis by Melichar, Volker O., Behr-Roussel, Delphine, Zabel, Ulrike, Uttenthal, L. Otto, Rodrigo, José, Rupin, Alain, Verbeuren, Tony J., Arun Kumar H. S., Harald H. H. W. Schmidt, Ignarro, Louis J.

“…Atherosclerosis is associated with alterations in nitric oxide (NO)/cGMP signaling. In early stages of the disease, inflammatory and possibly other cells…”
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Oxidative Stress and Endothelial Dysfunction in Aortas of Aged Spontaneously Hypertensive Rats by NOX1/2 Is Reversed by NADPH Oxidase Inhibition by Wind, Sven, Beuerlein, Knut, Armitage, Melanie E, Taye, Ashraf, Kumar, Arun H.S, Janowitz, Daniel, Neff, Christina, Shah, Ajay M, Wingler, Kirstin, Schmidt, Harald H.H.W

“…Arterial hypertension is associated with increased levels of reactive oxygen species, which may scavenge endothelium-derived NO and thereby diminish its…”
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Analysis of attitudes toward the source of progenitor cells in tissue-engineered products for use in burns compared with other disease states by Clover, Anthony J. P., Lane O'Neill, Billy, Kumar, Arun H. S.

“…The first trials using progenitor cells to improve burn wound healing are beginning. However, there remains a paucity of data on patients' opinions of the…”
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Multidetector Computed Tomography Accurately Defines Infarct Size, But Not Microvascular Obstruction After Myocardial Infarction by O'Sullivan, John F., MD, PhD, Leblond, Anne-Laure, PhD, O'Dea, John, MD, Hristova, Ivalina, BS, Kumar, Sujith, DMRIT, Martin, Kenneth, PhD, Kumar, Arun H.S., DVM, PhD, Caplice, Noel M., MD, PhD

“…[...]reduced RBF (impairing contrast penetration) may not be the only determinant of hypoenhancement on MDCT. [...]in this study, MDCT did not predict dynamic…”
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Date Palm ( Phoenix dactylifera ) Fruits as a Potential Cardioprotective Agent: The Role of Circulating Progenitor Cells by Alhaider, Ibrahim A, Mohamed, Maged E, Ahmed, K K M, Kumar, Arun H S

“…Date palms, along with their fruits' dietary consumption, possess enormous medicinal and pharmacological activities manifested in their usage in a variety of…”
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Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization by Kumar, Arun H S, Martin, Kenneth, Turner, Elizebeth C, Buneker, Chirlei K, Dorgham, Karim, Deterre, Philippe, Caplice, Noel M

“…Monocyte/macrophages are implicated in initiation of angiogenesis, tissue/organ perfusion and atherosclerosis biology. We recently showed that chemokine…”
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Bone marrow‐derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction by Kumar, Arun H. S., Metharom, Pat, Schmeckpeper, Jeff, Weiss, Sharon, Martin, Kenneth, Caplice, Noel M.

“…ABSTRACT Smooth muscle cells play a major role in numerous vascular diseases that contribute to remodeling, repair after injury, and arteriogenesis, and the…”
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A novel CX3CR1 antagonist eluting stent reduces stenosis by targeting inflammation by Ali, Mohammed T., Martin, Kenneth, Kumar, Arun H.S., Cavallin, Erika, Pierrou, Stefan, Gleeson, Birgitta M., McPheat, William L., Turner, Elizebeth C., Huang, Chien-Ling, Khider, Wisam, Vaughan, Carl, Caplice, Noel M.

“…We evaluated the therapeutic efficacy of a novel drug eluting stent (DES) inhibiting inflammation and smooth muscle cell (SMC) proliferation. We identified…”
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Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy by Saini, Anuj Kumar, Kumar H.S., Arun, Sharma, Shyam Sunder

“…Oxidative stress is implicated as a final common pathway in the development of diabetic neuropathy and pharmacological interventions targeted at inhibiting…”
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A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity–Brief Report by Metharom, Pat, Kumar, Arun H.S, Weiss, Sharon, Caplice, Noel M

“…OBJECTIVE—To determine whether CX3CR1 bone marrow cells have the capacity for smooth muscle cell (SMC) differentiation. METHODS AND RESULTS—CX3CR1 and CX3CR1…”
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Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis by Clover, Anthony J.P, Kumar, Arun H.S, Caplice, Noel M

“…Abstract The development of a good blood supply is a key step in burn wound healing and appears to be regulated in part by myeloid cells. CX3CR1 positive cells…”
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Intravascular cell delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion by Kumar, Arun H.S, Martin, Kenneth, Doyle, Brendan, Huang, Chien-Ling, Pillai, Gopala-Krishnan M, Ali, Mohammed T, Skelding, Kimberly A, Wang, Shaohua, Gleeson, Birgitta M, Jahangeer, Saleem, Ritman, Erik L, Russell, Stephen J, Caplice, Noel M

“…Abstract Site specific targeting remains elusive for gene and stem cell therapies in the cardiovascular field. One promising option involves use of devices…”
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Potent Long-Term Cardioprotective Effects of Single Low-Dose Insulin-Like Growth Factor-1 Treatment Postmyocardial Infarction by OʼSullivan, John F, Leblond, Anne-Laure, Kelly, Geraldine, Kumar, Arun H.S, Metharom, Pat, Büneker, Chirlei K, Alizadeh-Vikali, Niki, Hristova, Ivalina, Hynes, Brian G, OʼConnor, Rosemary, Caplice, Noel M

“…BACKGROUND—Insulin-like growth factor-1 (IGF-1) is recognized as an important regulator of cardiac structure and cardiomyocyte homeostasis. The prosurvival and…”
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A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells by Turner, Elizabeth C., Huang, Chien‐Ling, Sawhney, Neha, Govindarajan, Kalaimathi, Clover, Anthony J.P., Martin, Kenneth, Browne, Tara C., Whelan, Derek, Kumar, Arun H.S., Mackrill, John J., Wang, Shaohua, Schmeckpeper, Jeffrey, Stocca, Alessia, Pierce, William G., Leblond, Anne‐Laure, Cai, Liquan, O'Sullivan, Donnchadh M., Buneker, Chirlei K., Choi, Janet, MacSharry, John, Ikeda, Yasuhiro, Russell, Stephen J., Caplice, Noel M.

“…Disorders affecting smooth muscle structure/function may require technologies that can generate large scale, differentiated and contractile smooth muscle cells…”
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Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target by Metharom, Pat, Martin, Kenneth, Kumar, Arun H.S, Sawhney, Neha, Cronin, Michael F, McCarthy, Daniel G, Maguire, Anita R, Caplice, Noel M

“…Abstract Objectives We examined the role of C-fms+ cells in response to vascular injury with a focus on the temporal and spatial platelet interactions,…”
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Clinical Potential of Adult Vascular Progenitor Cells by Kumar, Arun H.S, Caplice, Noel M

“…Cell therapy to treat vascular and cardiovascular diseases has evolved over the past decade with improved understanding of progenitor cell mobilization,…”
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