Search Results - "Kumar, Boda Arun"

Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice by Sona, Chandan, Kumar, Ajeet, Dogra, Shalini, Kumar, Boda Arun, Umrao, Deepmala, Yadav, Prem N.

“…GPR40 (Free fatty acid receptor 1) has emerged as an important therapeutic target for diabetes. Several studies have demonstrated the association of comorbid…”
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Discovery of an isocoumarin analogue that modulates neuronal functions via neurotrophin receptor TrkB by Sudarshan, Kasireddy, Boda, Arun kumar, Dogra, Shalini, Bose, Ishani, Yadav, Prem Narayan, Aidhen, Indrapal Singh

“…[Display omitted] •Isocoumarin 1 preferentially binds to TrkB and act as an agonist.•Isocoumarin 1 induces phosporylation of TrkB (pY705) and…”
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Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression by Yadav, Anubhav, Dogra, Shalini, Boda, Arun Kumar, Kumari, Poonam, Kumar, Ajeet, Dash, Manish K., Yadav, Prem N.

“…Treatment-resistant depression (TRD) occurs in almost 50% of the depressed patients. Central kappa opioid receptor (KOR) agonism has been demonstrated to…”
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GloSensor assay for discovery of GPCR-selective ligands by Kumar, Boda Arun, Kumari, Poonam, Sona, Chandan, Yadav, Prem N

“…G protein-coupled receptors (GPCRs) are modulators of almost every physiological process, and therefore, are most favorite therapeutic target for wide spectrum…”
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