Search Results - "Kumar, B S Hemanth"

Lactoferrin-conjugated pH and redox-sensitive polymersomes based on PEG-S-S-PLA-PCL-OH boost delivery of bacosides to the brain by Goyal, Kritika, Konar, Arpita, Kumar, B S Hemanth, Koul, Veena

“…In the present study, engineered lactoferrin (Lf)-conjugated pH and redox-sensitive polymersomes derived from the triblock copolymer polyethylene…”
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Mn(II) based T1 and T2 potential MRI contrast agent appended with tryptamine: Recognition moiety for Aβ-plaques by Rastogi, Neeraj, Tyagi, Nidhi, Singh, Ovender, Hemanth Kumar, B.S., Singh, Udai P., Ghosh, Kaushik, Roy, Raja

“…We report the synthesis and characterization of manganese(II) complexes having pentadentate ligands L1…”
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Early detection of whole body radiation induced microstructural and neuroinflammatory changes in hippocampus: A diffusion tensor imaging and gene expression study by Gupta, Mamta, Mishra, Sushanta Kumar, Kumar, B.S. Hemanth, Khushu, Subash, Rana, Poonam

“…Ionizing radiation is known to a cause systemic inflammatory response within hours of exposure that may affect the central nervous system (CNS). The present…”
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Radiation-induced early changes in the brain and behavior: Serial diffusion tensor imaging and behavioral evaluation after graded doses of radiation by Trivedi, Richa, Khan, Ahmad Raza, Rana, Poonam, Haridas, Seenu, Hemanth Kumar, B.S., Manda, Kailash, Rathore, Ram K.S., Tripathi, Rajendra P., Khushu, Subash

“…The nuclear arsenal and the use of nuclear technologies have enhanced the likelihood of whole‐body/partial‐body radiation exposure. The central nervous system…”
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NMR based metabolomics reveals acute hippocampal metabolic fluctuations during cranial irradiation in murine model by Rana, Poonam, Gupta, Mamta, Khan, Ahmad Raza, Hemanth Kumar, B S, Roy, Raja, Khushu, Subash

“…Cranial irradiation is widely used as a treatment modality or prophylactic treatment in cancer patients, but it is frequently related to neurocognitive…”
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Gd(III)‐DO3A‐SBMPP:An Effort to Develop the MRI Contrast Agent with Enhanced Relaxivity by Rangaswamy, Sandhya, Varshney, Raunak, Tiwari, Anjani K., Sethi, Swarndeep K., Hemanth kumar, B. S., Ojha, Himanshu, Sandeep Kaur‐Ghumaan, Mishra, Anil K.

“…Rational design of a new class of MR (magnetic resonance) contrast agent for enhance relaxivity has been described. The click chemistry was employed to…”
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Early monitoring and quantitative evaluation of macrophage infiltration after experimental traumatic brain injury: A magnetic resonance imaging and flow cytometric analysis by Mishra, Sushanta Kumar, Kumar, B. S. Hemanth, Khushu, Subash, Singh, Ajay K, Gangenahalli, Gurudutta

“…The inflammatory response following traumatic brain injury (TBI) is regulated by phagocytic cells. These cells comprising resident microglia and infiltrating…”
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Neurodegenerative evidences during early onset of depression in CMS rats as detected by proton magnetic resonance spectroscopy at 7 T by Hemanth Kumar, B S, Mishra, Sushanta Kumar, Rana, Poonam, Singh, Sadhana, Khushu, Subash

“…Depression is a complex psychiatric disorder characterized by anhedonia and feeling of sadness and chronic mild stress (CMS) seems to be a valuable animal…”
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Increased transverse relaxivity in ultrasmall superparamagnetic iron oxide nanoparticles used as MRI contrast agent for biomedical imaging by Mishra, Sushanta Kumar, Kumar, B S Hemanth, Khushu, Subash, Tripathi, Rajendra P, Gangenahalli, Gurudutta

“…Synthesis of a contrast agent for biomedical imaging is of great interest where magnetic nanoparticles are concerned, because of the strong influence of…”
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Demyelinating evidences in CMS rat model of depression: A DTI study at 7 T by Hemanth Kumar, B.S, Mishra, S.K, Trivedi, R, Singh, S, Rana, P, Khushu, S

“…Highlights • Altered DTI indices can elucidate microstructural changes in depression. • Increased λ ⊥ was the primary factor driving FA reduction. • Increased…”
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Metal Based Imaging Probes of DO3A-Act-Met for LAT1 Mediated Methionine Specific Tumors : Synthesis and Preclinical Evaluation by Kadiyala, K Ganesh, Datta, Anupama, Tanwar, Jyoti, Adhikari, Anupriya, Kumar, B. S. Hemanth, Chuttani, Krishna, Thirumal, Meganathan, Mishra, Anil K.

“…ABSTRACT Purpose Tumor cells are known to have an elevated requirement for methionine due to increased protein synthesis and trans-methylation reactions. A…”
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Comparative evaluation of brain neurometabolites and DTI indices following whole body and cranial irradiation: a magnetic resonance imaging and spectroscopy study by Gupta, Mamta, Rana, Poonam, Trivedi, Richa, Kumar, B. S. Hemanth, Khan, Ahmad Raza, Soni, Ravi, Rathore, R. K. S., Khushu, Subash

“…Understanding early differential response of brain during whole body radiation or cranial radiation exposure is of significant importance for better injury…”
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Evaluation of biotinylated magnetic nanoparticles for tumour imaging by Chauhan, Ram Prakash, Mathur, Rashi, Singh, Gurjaspreet, Bag, Narmada, Singh, Sweta, Chuttani, Krishna, Kumar, B. S. Hemanth, Agrawal, Satyam K., Mishra, Anil K.

“…Target-specific nanoparticles with good stability, dispersibility and targeting properties are very desirable for in vivo applications like diagnosis and…”
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Altered brain metabolism after whole body irradiation in mice: A preliminary in vivo 1H MRS study by Rana, Poonam, Khan, Ahmad Raza, Modi, Shilpi, Hemanth Kumar, B. S., Javed, Salim, Tripathi, Rajendra Prasad, Khushu, Subash

“…Abstract Purpose: In the classical description of acute radiation syndrome, the role of central nervous system (CNS) is underestimated. It is now well…”
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Demyelinating evidences in CMS rat model of depression: A DTI study at 7T by Kumar, Hemanth, Mishra, S K, Trivedi, R, Singh, S, Rana, P, Khushu, S

“…Depression is among the most debilitating diseases worldwide. Long-term exposure to stressors plays a major role in development of human depression. Chronic…”
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Neurodegenerative evidences during early onset of depression in CMS rats as detected by proton magnetic resonance spectroscopy at 7T by Hemanth Kumar, B.S., Mishra, Sushanta Kumar, Rana, Poonam, Singh, Sadhana, Khushu, Subash

“…► A decreasing trend was observed in most of the metabolites in CMS rats as compared to control. ► Significant increase in myo-inositol and taurine was found…”
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Mn(II) based T 1 and T 2 potential MRI contrast agent appended with tryptamine: Recognition moiety for Aβ-plaques by Rastogi, Neeraj, Tyagi, Nidhi, Singh, Ovender, Hemanth Kumar, B S, Singh, Udai P, Ghosh, Kaushik, Roy, Raja

“…We report the synthesis and characterization of manganese(II) complexes having pentadentate ligands L…”
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Altered brain metabolism after whole body irradiation in mice: A preliminary in vivo 1 H MRS study by Rana, Poonam, Khan, Ahmad Raza, Modi, Shilpi, Hemanth Kumar, B. S., Javed, Salim, Tripathi, Rajendra Prasad, Khushu, Subash

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