Search Results - "Kumar, Aditi"

Iron Therapy in Inflammatory Bowel Disease by Kumar, Aditi, Brookes, Matthew J

“…The most common complication seen in inflammatory bowel disease (IBD) patients is iron deficiency anaemia (IDA). Symptoms such as chronic fatigue can be as…”
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Iron deficiency anaemia: pathophysiology, assessment, practical management by Kumar, Aditi, Sharma, Esha, Marley, Alexandra, Samaan, Mark A, Brookes, Matthew James

“…The WHO has recognised iron deficiency anaemia (IDA) as the most common nutritional deficiency in the world, with 30% of the population being affected with…”
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Horizon scanning: new and future therapies in the management of inflammatory bowel disease by Philip J Smith, Aditi Kumar

“…The current mainstay treatment modalities for inflammatory bowel disease (IBD) include immunomodulators (methotrexate and thiopurines), biologics (antitumour…”
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A review of the therapeutic management of Crohn’s disease by Kumar, Aditi, Cole, Alexander, Segal, Jonathan, Smith, Philip, Limdi, Jimmy K.

“…Crohn’s disease is a chronic inflammatory, relapsing-remitting, and progressive gastrointestinal disorder with an often-negative impact on the physical,…”
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Influence of Iron on the Gut Microbiota in Colorectal Cancer by Phipps, Oliver, Al-Hassi, Hafid O, Quraishi, Mohammed N, Kumar, Aditi, Brookes, Matthew J

“…Perturbations of the colonic microbiota can contribute to the initiation and progression of colorectal cancer, leading to an increase in pathogenic bacteria at…”
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The UPTAKE study: a cross-sectional survey examining the insights and beliefs of the UK population on COVID-19 vaccine uptake and hesitancy by Sethi, Sonika, Kumar, Aditi, Mandal, Anandadeep, Shaikh, Mohammed, Hall, Claire A, Kirk, Jeremy M W, Moss, Paul, Brookes, Matthew J, Basu, Supratik

“…ObjectiveA key challenge towards a successful COVID-19 vaccine uptake is vaccine hesitancy. We examine and provide novel insights on the key drivers and…”
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Bile Acids and the Microbiome: Making Sense of This Dynamic Relationship in Their Role and Management in Crohn’s Disease by Kumar, Aditi, Al-Hassi, Hafid O., Steed, Helen, Phipps, Oliver, Brookes, Matthew J.

“…Background. Bile acids help maintain the physiological balance of the gut microbiome and the integrity of the intestinal epithelial barrier. Similarly,…”
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A single faecal bile acid stool test demonstrates potential efficacy in replacing SeHCAT testing for bile acid diarrhoea in selected patients by Kumar, Aditi, Al-Hassi, Hafid O., Jain, Manushri, Phipps, Oliver, Ford, Clare, Gama, Rousseau, Steed, Helen, Butterworth, Jeffrey, McLaughlin, John, Galbraith, Niall, Brookes, Matthew J., Hughes, Lauren E.

“…This study examines the validity of measuring faecal bile acids (FBA) in a single stool sample as a diagnostic tool for bile acid diarrhoea (BAD) by direct…”
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COVID-19 Diagnostics, Tools, and Prevention by Allam, Mayar, Cai, Shuangyi, Ganesh, Shambavi, Venkatesan, Mythreye, Doodhwala, Saurabh, Song, Zexing, Hu, Thomas, Kumar, Aditi, Heit, Jeremy, Study Group, Covid, Coskun, Ahmet F

“…The Coronavirus Disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), outbreak from Wuhan City, Hubei province,…”
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Efficacy and safety of medical therapies in microscopic colitis: a systematic review and network meta-analysis by Kumar, Aditi, Hiner, George, Brookes, Matthew J., Segal, Jonathan P.

“…Background: The mainstay of treatment for microscopic colitis (MC) is budesonide. However, the optimal formulation and dosage of budesonide to induce and…”
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The impact of treatment with bile acid sequestrants on quality of life in patients with bile acid diarrhoea by Kumar, Aditi, Galbraith, Niall, Al-Hassi, Hafid O, Jain, Manushri, Phipps, Oliver, Butterworth, Jeffrey, Steed, Helen, McLaughlin, John, Brookes, Matthew J

“…Abstract Background Bile acid diarrhoea (BAD) can be severely debilitating and negatively affect patients’ quality of life (QoL). We carried out a multi-centre…”
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Paediatric sickle cell disease presenting with hepatobiliary symptoms—a case presentation and brief literature review by Kumar, Aditi, Behera, Rashmi Ranjan, Mahapatro, Samarendra, Patel, Ranjan, Nayak, Hemanta, Satapathy, Amit Kumar

“…Background Sickle hepatopathy is the hepatobiliary dysfunction associated with sickle cell disease. It has a varied spectrum ranging from asymptomatic…”
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Controversies in Venous Thromboembolism Risk Assessment in Inflammatory Bowel Disease: A Narrative Review by Sharma, Nikhil, Tewatia, Pavit, Harvey, Philip R, Kumar, Aditi

“…Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract with increasing rates of incidence and prevalence…”
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Personalised medicine in IBD: don’t dispose of the sledgehammer just yet by Kumar, Aditi, Brookes, Matthew J, Segal, Jonathan P

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The UPTAKE study: implications for the future of COVID-19 vaccination trial recruitment in UK and beyond by Sethi, Sonika, Kumar, Aditi, Mandal, Anandadeep, Shaikh, Mohammed, Hall, Claire A, Kirk, Jeremy M W, Moss, Paul, Brookes, Matthew J, Basu, Supratik

“…Developing a safe and effective vaccine will be the principal way of controlling the COVID-19 pandemic. However, current COVID-19 vaccination trials are not…”
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The analysis of gut microbiota in patients with bile acid diarrhoea treated with colesevelam by Kumar, Aditi, Quraishi, Mohammed Nabil, Al-Hassi, Hafid O, El-Asrag, Mohammed E, Segal, Jonathan P, Jain, Manushri, Steed, Helen, Butterworth, Jeffrey, Farmer, Adam, Mclaughlin, John, Beggs, Andrew, Brookes, Matthew J

“…Bile acid diarrhoea (BAD) is a common disorder that results from an increased loss of primary bile acids and can result in a change in microbiome. The aims of…”
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Clinical and microbiological features of infection in alcoholic hepatitis: an international cohort study by Parker, Richard, Im, Gene, Jones, Fiona, Hernández, Onan Pérez, Nahas, Jonathan, Kumar, Aditi, Wheatley, Daniel, Sinha, Ashish, Gonzalez-Reimers, Emilio, Sanchez-Pérez, María, Ghezzi, Antonella, David, Miruna Delia, Corbett, Christopher, McCune, Anne, Aithal, Guruprasad Padur, Holt, Andrew, Stewart, Stephen

“…Background Previous studies have described the clinical impact of infection in alcoholic hepatitis (AH) but none have comprehensively explored the…”
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Differences in the On- and Off-Tumor Microbiota between Right- and Left-Sided Colorectal Cancer by Phipps, Oliver, Quraishi, Mohammed N., Dickson, Edward A., Steed, Helen, Kumar, Aditi, Acheson, Austin G., Beggs, Andrew D., Brookes, Matthew J., Al-Hassi, Hafid Omar

“…This study aims to determine differences in the on- and off-tumor microbiota between patients with right- and left-sided colorectal cancer. Microbiome…”
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Large-scale neuroanatomy using LASSO: Loop-based Automated Serial Sectioning Operation by Lee, Timothy J, Kumar, Aditi, Balwani, Aishwarya H, Brittain, Derrick, Kinn, Sam, Tovey, Craig A, Dyer, Eva L, da Costa, Nuno M, Reid, R Clay, Forest, Craig R, Bumbarger, Daniel J

“…Serial section transmission electron microscopy (ssTEM) is the most promising tool for investigating the three-dimensional anatomy of the brain with nanometer…”
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Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity by Marsili, Alessandro, Aguayo-Mazzucato, Cristina, Chen, Ting, Kumar, Aditi, Chung, Mirra, Lunsford, Elaine P, Harney, John W, Van-Tran, Thuy, Gianetti, Elena, Ramadan, Waile, Chou, Cyril, Bonner-Weir, Susan, Larsen, Philip Reed, Silva, Jorge Enrique, Zavacki, Ann Marie

“…The type 2 iodothyronine deiodinase (D2) converts the pro-hormone thyroxine into T3 within target tissues. D2 is essential for a full thermogenic response of…”
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