Search Results - "Kumamoto, Takuya"

Palladium-Catalyzed Reductive Heck Hydroarylation of Unactivated Alkenes Using Hydrosilane at Room Temperature by Shirai, Takahiro, Migitera, Yusuke, Nakajima, Ryo, Kumamoto, Takuya

“…The reductive Heck hydroarylation of unactivated alkenes has emerged as an essential reaction for regioselective hydroarylation. Herein, we report a…”
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Asymmetric Total Synthesis of Brasiliquinones B and C via Oxidative Cyclization of a Hydroquinone-Silyl Enol Ether Hybrid by Miyake, Hiroki, Nakajima, Ryo, Kumamoto, Takuya

“…The asymmetric total synthesis of angucycline antibiotics (S)-brasiliquinones B and C was accomplished. The benz­[a]­anthraquinone core was constructed via…”
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Palladium-Catalyzed Site-Selective Hydrogenation of Unactivated Alkenes Directed by 8-Aminoquinoline Amides by Shirai, Takahiro, Tani, Shinnosuke, Nakajima, Ryo, Kumamoto, Takuya

“…We have developed a method for the site-selective hydrogenation of unactivated alkenes using 8-aminoquinoline amide as the directing group. For unactivated…”
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Study of Palladium-Catalyzed Site and Regioselective Reductive Heck Hydroarylation of Unactivated Alkene by Shirai, Takahiro, Nakajima, Ryo, Kumamoto, Takuya

“…We studied the reaction pathway of our reductive Heck hydroarylation using a palladium catalyst and a hydrosilane. A key question to verify the reaction…”
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Chemoselective Hydrogenation of α,β-Unsaturated Anilides Catalyzed by Palladium-Hydrosilane System by Shirai, Takahiro, Tani, Shinnosuke, Nakajima, Ryo, Kumamoto, Takuya

“…We report chemoselective hydrogenation of α,β-unsaturated anilides catalyzed by the palladium-polymethylhydrosiloxane (hydrosilane) system. Under this…”
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Direct N1-Selective Alkylation of Hydantoins Using Potassium Bases by Shintani, Yumi, Kato, Koichi, Kawami, Masashi, Takano, Mikihisa, Kumamoto, Takuya

“…Hydantoins, including the antiepileptic drug phenytoin, contain an amide nitrogen and an imide nitrogen, both of which can be alkylated. However, due to the…”
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Chemistry of Anti-HIV Active Trimeric Pyranonaphthoquinone Conocurvone: Synthetic Studies towards Monomeric Teretifolione B and Related Compounds by Kumamoto, Takuya, Katakawa, Kazuaki

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Total Synthesis of 6-Deoxydihydrokalafungin, a Key Biosynthetic Precursor of Actinorhodin, and Its Epimer by Kumamoto, Takuya, Kainuma, Mika, Takahashi, Azusa, Matsuo, Yoshika, Katakawa, Kazuaki, Taguchi, Takaaki, Ichinose, Koji

“…In this article, we report the total synthesis of 6-deoxydihydrokalafungin (DDHK), a key biosynthetic intermediate of a dimeric benzoisochromanequinone…”
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Total Synthesis of (±)-4-Deoxyblennolide C via Spirochromanone by Kumamoto, Takuya, Hasegawa, Sho, Adachi, Kanna, Katakawa, Kazuaki

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Asymmetric total syntheses of teretifolione B and methylteretifolione B via Diels-Alder reaction of optically active pyranobenzyne and substituted furans by Katakawa, Kazuaki, Kainuma, Mika, Suzuki, Katsuya, Tanaka, Saori, Kumamoto, Takuya

“…We report the asymmetric total syntheses of teretifolione B and methylteretifolione B, which are benzochromenes originally isolated from Conospermum plants…”
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Electrolyte-dependence of the macroscopic textures generated in the colloidal liquid crystals of niobate nanosheets by Zhang, Jie, Morisaka, Keisuke, Kumamoto, Takuya, Mouri, Emiko, Nakato, Teruyuki

“…[Display omitted] Liquid crystalline aqueous colloids of inorganic nanosheets with thickness of 1 nm and lateral size of several micrometers were prepared from…”
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Unveiling Two Consecutive Hydroxylations: Mechanisms of Aromatic Hydroxylations Catalyzed by Flavin‐Dependent Monooxygenases for the Biosynthesis of Actinorhodin and Related Antibiotics by Hashimoto, Makoto, Taguchi, Takaaki, Ishikawa, Kazuki, Mori, Ryuichiro, Hotta, Akari, Watari, Susumu, Katakawa, Kazuaki, Kumamoto, Takuya, Okamoto, Susumu, Ichinose, Koji

“…Flavin‐dependent monooxygenases are ubiquitous in living systems and are classified into single‐ or two‐component systems. Actinorhodin, produced by…”
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Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells by Noguchi, Soma, Kajimoto, Taketoshi, Kumamoto, Takuya, Shingai, Masashi, Narasaki, Soshi, Urabe, Tomoaki, Imamura, Serika, Harada, Kana, Hide, Izumi, Tanaka, Sigeru, Yanase, Yuhki, Nakamura, Shun-Ichi, Tsutsumi, Yasuo M., Sakai, Norio

“…Background and purpose: In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C…”
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Preparation of Optically Active 2,2-Disubstituted 5-Hydroxychromenes by the Enzymatic Resolution of Racemic Esters by Kumamoto, Takuya, Kainuma, Mika, Yamada, Ai, Katakawa, Kazuaki

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Guanidine-Catalyzed Asymmetric Synthesis of 2,2-Disubstituted Chromane Skeletons by Intramolecular Oxa-Michael Addition by Saito, Noriko, Ryoda, Akemi, Nakanishi, Waka, Kumamoto, Takuya, Ishikawa, Tsutomu

“…The guanidine‐catalyzed 6‐exo‐trig‐type intramolecular asymmetric oxa‐Michael addition of α,β‐unsaturated esters with a 2‐hydroxyaryl moiety at the C‐5 carbon…”
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Enantioselective Construction of a Polyhydroxylated Pyrrolidine Skeleton from 3‑Vinylaziridine-2-carboxylates: Synthesis of (+)-DMDP and a Potential Common Intermediate for (+)-Hyacinthacine A1 and (+)-1-epi-Australine by Kondo, Yukari, Suzuki, Noriyuki, Takahashi, Masato, Kumamoto, Takuya, Masu, Hyuma, Ishikawa, Tsutomu

“…We report an enantioselective synthesis of the polyhydroxylated pyrrolidine alkaloid (+)-DMDP. The key steps in the synthesis were guanidinium ylide mediated…”
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Catalytic Performance of Polystyrene-Bound ChibaG Derivatives as Guanidine Organobases in Asymmetric Michael Additions by Ishikawa, Tsutomu, Heima, Takashi, Yoshida, Makoto, Kumamoto, Takuya

“…The guanidine organocatalyst, ChibaG, was bound via an ether linkage to the phenyl group of the 2‐imino substituent to Merrifield resin. Polystyrene‐bound…”
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Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers by Kumamoto, Takuya, Nakajima, Marie, Uga, Reina, Ihayazaka, Naoko, Kashihara, Haruna, Katakawa, Kazuaki, Ishikawa, Tsutomu, Saiki, Ryotaro, Nishimura, Kazuhiro, Igarashi, Kazuei

“…[Display omitted] N-Methyl-d-aspartate (NMDA) receptors have been implicated in learning and memory, and may also play a central role in various conditions…”
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Optical trapping and orientation manipulation of 2D inorganic materials using a linearly polarized laser beam by Tominaga, Makoto, Higashi, Yuki, Kumamoto, Takuya, Nagashita, Takashi, Nakato, Teruyuki, Suzuki, Yasutaka, Kawamata, Jun

“…Because inorganic nanosheets, such as clay minerals, are anisotropic, the manipulation of nanosheet orientation is an important challenge in order to realize…”
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Synthesis of (−)-benzolactam-V8 by application of asymmetric aziridination by Khantikaew, Itsara, Takahashi, Masato, Kumamoto, Takuya, Suzuki, Noriyuki, Ishikawa, Tsutomu

“…(−)-Benzolactam-V8, an artificially-designed cyclic dipeptide with strong tumor-promoter activity, was synthesized from benzyl ( S)- N-(2-formylphenyl)-…”
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