Search Results - "Kulsuptrakul, Jessie"
-
1
XaaP-ing DPP8/9 for CARD8 activation
Published in Nature chemical biology (01-05-2022)“…Inflammasomes are cytosolic immune complexes that initiate inflammatory signaling upon pathogen recognition. A new paper reveals that inhibition of M24B…”
Get full text
Journal Article -
2
A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection
Published in eLife (07-07-2023)“…Inflammasomes are cytosolic innate immune complexes that assemble upon detection of diverse pathogen-associated cues and play a critical role in host defense…”
Get full text
Journal Article -
3
The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins
Published in eLife (13-09-2019)“…Flaviviruses translate their genomes as multi-pass transmembrane proteins at the endoplasmic reticulum (ER) membrane. Here, we show that the ER membrane…”
Get full text
Journal Article -
4
CARD8 Inflammasome Activation Upon HIV-1 Infection
Published 01-01-2024“…Inflammasomes are host cytosolic innate immune complexes that assemble upon detection of diverse pathogen-associated cues and play a crucial role in host…”
Get full text
Dissertation -
5
Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses
Published in Cell (07-01-2021)“…The Coronaviridae are a family of viruses that cause disease in humans ranging from mild respiratory infection to potentially lethal acute respiratory distress…”
Get full text
Journal Article -
6
A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
Published in Cell reports (Cambridge) (16-03-2021)“…Hepatitis A virus (HAV) is a positive-sense RNA virus causing acute inflammation of the liver. Here, using a genome-scale CRISPR screen, we provide a…”
Get full text
Journal Article -
7
The Dihydroquinolizinone Compound RG7834 Inhibits the Polyadenylase Function of PAPD5 and PAPD7 and Accelerates the Degradation of Matured Hepatitis B Virus Surface Protein mRNA
Published in Antimicrobial agents and chemotherapy (16-12-2020)“…Hepatitis B virus (HBV) mRNA metabolism is dependent upon host proteins PAPD5 and PAPD7 (PAPD5/7). PAPD5/7 are cellular, noncanonical, poly(A) polymerases…”
Get full text
Journal Article -
8
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome
Published in PLoS biology (01-06-2023)“…Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors…”
Get full text
Journal Article -
9
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome
Published in PLoS biology (08-06-2023)“…Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors…”
Get full text
Journal Article -
10
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
Published in PLoS pathogens (28-10-2020)“…About the Authors: Emily D. Crawford Affiliations Chan Zuckerberg Biohub, San Francisco, California, United States of America, University of California San…”
Get full text
Journal Article