Search Results - "Kulp, Kristen"

Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array by Lam, Doris, Enright, Heather A., Cadena, Jose, Peters, Sandra K. G., Sales, Ana Paula, Osburn, Joanne J., Soscia, David A., Kulp, Kristen S., Wheeler, Elizabeth K., Fischer, Nicholas O.

“…The brain’s extracellular matrix (ECM) is a macromolecular network composed of glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro…”
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Simultaneous electrical recording of cardiac electrophysiology and contraction on chip by Qian, Fang, Huang, Chao, Lin, Yi-Dong, Ivanovskaya, Anna N, O'Hara, Thomas J, Booth, Ross H, Creek, Cameron J, Enright, Heather A, Soscia, David A, Belle, Anna M, Liao, Ronglih, Lightstone, Felice C, Kulp, Kristen S, Wheeler, Elizabeth K

“…Prevailing commercialized cardiac platforms for in vitro drug development utilize planar microelectrode arrays to map action potentials, or impedance sensing…”
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Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model by Enright, Heather A, Falso, Miranda J S, Malfatti, Michael A, Lao, Victoria, Kuhn, Edward A, Hum, Nicholas, Shi, Yilan, Sales, Ana Paula, Haack, Kurt W, Kulp, Kristen S, Buchholz, Bruce A, Loots, Gabriela G, Bench, Graham, Turteltaub, Kenneth W

“…Triclocarban (TCC) is among the top 10 most commonly detected wastewater contaminants in both concentration and frequency. Its presence in water, as well as…”
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Optimizing cell encapsulation condition in ECM-Collagen I hydrogels to support 3D neuronal cultures by Lam, Doris, Enright, Heather A., Peters, Sandra K.G., Moya, Monica L., Soscia, David A., Cadena, Jose, Alvarado, Javier A., Kulp, Kristen S., Wheeler, Elizabeth K., Fischer, Nicholas O.

“…[Display omitted] •We evaluated the viability and distribution of cells in a 3D neuronal culture.•Culture conditions during collagen fibrillogenesis were…”
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Functional and transcriptional characterization of complex neuronal co-cultures by Enright, Heather A., Lam, Doris, Sebastian, Aimy, Sales, Ana Paula, Cadena, Jose, Hum, Nicholas R., Osburn, Joanne J., Peters, Sandra K. G., Petkus, Bryan, Soscia, David A., Kulp, Kristen S., Loots, Gabriela G., Wheeler, Elizabeth K., Fischer, Nicholas O.

“…Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell culture on an engineered platform. It is a noninvasive tool to…”
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Prostate cancer invasion and metastasis: insights from mining genomic data by Hudson, Bryan D, Kulp, Kristen S, Loots, Gabriela G

“…Prostate cancer (PCa) is the second most commonly diagnosed malignancy in men in the Western world and the second leading cause of cancer-related deaths among…”
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D‐Lactate production as a function of glucose metabolism in Saccharomyces cerevisiae by Stewart, Benjamin J., Navid, Ali, Kulp, Kristen S., Knaack, Jennifer L. S., Bench, Graham

“…Methylglyoxal, a reactive, toxic dicarbonyl, is generated by the spontaneous degradation of glycolytic intermediates. Methylglyoxal can form covalent adducts…”
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Preparation of Single Cells for Imaging/Profiling Mass Spectrometry by Berman, Elena S.F., Fortson, Susan L., Checchi, Kyle D., Wu, Ligang, Felton, James S., Wu, Kuang Jen J., Kulp, Kristen S.

“…Characterizing chemical changes within individual cells is important for determining fundamental mechanisms of biological processes that will lead to new…”
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Chemical and Biological Differentiation of Three Human Breast Cancer Cell Types Using Time-of-Flight Secondary Ion Mass Spectrometry by Kulp, Kristen S, Berman, Elena S. F, Knize, Mark G, Shattuck, David L, Nelson, Erik J, Wu, Ligang, Montgomery, Jennifer L, Felton, James S, Wu, Kuang Jen

“…We use time-of-flight secondary ion mass spectrometry (TOF-SIMS) to image and classify individual cells on the basis of their characteristic mass spectra…”
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Distinguishing Monosaccharide Stereo- and Structural Isomers with TOF-SIMS and Multivariate Statistical Analysis by Berman, Elena S. F., Kulp, Kristen S., Knize, Mark G., Wu, Ligang, Nelson, Erik J., Nelson, David O., Wu, Kuang Jen

“…Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is utilized to examine the mass spectra and fragmentation patterns of seven isomeric monosaccharides…”
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Chemometric and statistical analyses of ToF-SIMS spectra of increasingly complex biological samples by Berman, Elena S. F., Wu, Ligang, Fortson, Susan L., Kulp, Kristen S., Nelson, David O., Wu, Kuang Jen

“…Characterizing and classifying molecular variations within biological samples are critical for determining the fundamental mechanisms of biological processes…”
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An in vitro model system to predict the bioaccessibility of heterocyclic amines from a cooked meat matrix by Kulp, Kristen S., Fortson, Susan L., Knize, Mark G., Felton, James S.

“…To understand the impact of variation in digestion parameters on the release of heterocyclic amines naturally formed during cooking, we developed and…”
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Human exposure to heterocyclic amine food mutagens/carcinogens: Relevance to breast cancer by Felton, James S., Knize, Mark G., Salmon, Cynthia P., Malfatti, Michael A., Kulp, Kristen S.

“…Heterocyclic amines produced from overcooked foods are extremely mutagenic in numerous in vitro and in vivo test systems. One of these mutagens,…”
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Impact of environmental exposures on the mutagenicity/carcinogenicity of heterocyclic amines by Felton, James S., Knize, Mark G., Bennett, L.Michelle, Malfatti, Michael A., Colvin, Michael E., Kulp, Kristen S.

“…Carcinogenic heterocyclic amines are produced from overcooked foods and are highly mutagenic in most short-term test systems. One of the most abundant of these…”
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The identification of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans by Malfatti, Michael A., Kulp, Kristen S., Knize, Mark G., Davis, Cindy, Massengill, Joyce P., Williams, Suzanne, Nowell, Susan, MacLeod, Stewart, Dingley, Karen H., Turteltaub, Kenneth W., Lang, Nicholas P., Felton, James S.

“…[2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine ([14C]PhIP), a putative human carcinogenic heterocyclic amine found in well-done cooked meat, was…”
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Essiac® and Flor-Essence® herbal tonics stimulate the in vitro growth of human breast cancer cells by KULP, Kristen S, MONTGOMERY, Jennifer L, NELSON, David O, CUTTER, Beth, LATHAM, E. Ray, SHATTUCK, David L, KLOTZ, Diane M, BENNETT, L. Michelle

“…People diagnosed with cancer often self-administer complementary and alternative medicines (CAMs) to supplement their conventional treatments, improve health,…”
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PhIP Carcinogenicity in Breast Cancer:  Computational and Experimental Evidence for Competitive Interactions with Human Estrogen Receptor by Bennion, Brian J, Cosman, Monique, Lightstone, Felice C, Knize, Mark G, Montgomery, Jennifer L, Bennett, L. Michelle, Felton, James S, Kulp, Kristen S

“…Many carcinogens have been shown to cause tissue specific tumors in animal models. The mechanism for this specificity has not been fully elucidated and is…”
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Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans by Kulp, Kristen S., Knize, Mark G., Malfatti, Michael A., Salmon, Cynthia P., Felton, James S.

“…Many studies suggest that mutagenic/carcinogenic chemicals in the diet, like 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), may play a role in human…”
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Imaging and differentiation of mouse embryo tissues by ToF-SIMS by Wu, Ligang, Lu, Xiaochen, Kulp, Kristen S., Knize, Mark G., Berman, Elena S.F., Nelson, Erik J., Felton, James S., Wu, Kuang Jen J.

“…Time-of-flight secondary ion mass spectrometry (ToF-SIMS) equipped with a gold ion gun was used to image mouse embryo sections and differentiate tissue types…”
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Herbal tonic does not inhibit estrogen receptor negative mammary tumor development in a transgenic mouse model by Bennett, L Michelle, Montgomery, Jennifer L, Collins, N Keith, Steinberg, Seth M, Kulp, Kristen S

“…Women who are diagnosed with breast cancer often self-administer complementary and alternative medicines to augment their conventional treatments, improve…”
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