Search Results - "Kullberg, Bart Jan"
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Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-07-2016)“…Summary Background Antimicrobial stewardship is advocated to improve the quality of antimicrobial use. We did a systematic review and meta-analysis to assess…”
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Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes
Published in Cell host & microbe (16-08-2012)“…Immunological memory in vertebrates is often exclusively attributed to T and B cell function. Recently it was proposed that the enhanced and sustained innate…”
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An Exaggerated Monocyte-Derived Cytokine Response to Candida Hyphae in Patients With Recurrent Vulvovaginal Candidiasis
Published in The Journal of infectious diseases (16-05-2022)“…Abstract Background Recurrent vulvovaginal candidiasis (RVVC) affects up to 8% of women. The immunopathogenesis is poorly understood but it has been suggested…”
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Human TLR10 is an anti-inflammatory pattern-recognition receptor
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2014)“…Toll-like receptor (TLR)10 is the only pattern-recognition receptor without known ligand specificity and biological function. We demonstrate that TLR10 is a…”
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Interplay between Candida albicans and the Mammalian Innate Host Defense
Published in Infection and Immunity (01-04-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America
Published in Clinical infectious diseases (01-03-2009)“…Guidelines for the management of patients with invasive candidiasis and mucosal candidiasis were prepared by an Expert Panel of the Infectious Diseases Society…”
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Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages
Published in Cellular microbiology (01-10-2008)“…The β-glucan receptor dectin-1 and Toll-like receptors TLR2 and TLR4 are the main receptors for recognition of Candida albicans by the innate immune system. It…”
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The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis
Published in European journal of immunology (01-08-2011)“…The Nlrp3 inflammasome has been proposed to play an important role in antifungal host defense. However, studies exploring the role of the inflammasome in…”
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Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors
Published in European journal of immunology (01-02-2008)“…Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others…”
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Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris
Published in Nature microbiology (01-12-2020)“…Candida auris is among the most important emerging fungal pathogens, yet mechanistic insights into its immune recognition and control are lacking. Here, we…”
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A comprehensive genetic map of cytokine responses in Lyme borreliosis
Published in Nature communications (07-05-2024)“…The incidence of Lyme borreliosis has risen, accompanied by persistent symptoms. The innate immune system and related cytokines are crucial in the host…”
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Diagnostic parameters of cellular tests for Lyme borreliosis in Europe (VICTORY study): a case-control study
Published in The Lancet infectious diseases (01-09-2022)“…Cellular tests for Lyme borreliosis might be able to overcome major shortcomings of serological testing, such as its low sensitivity in early stages of…”
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Inflammasome-independent modulation of cytokine response by autophagy in human cells
Published in PloS one (07-04-2011)“…Autophagy is a cell housekeeping mechanism that has recently received attention in relation to its effects on the immune response. Genetic studies have…”
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Recognition and Blocking of Innate Immunity Cells by Candida albicans Chitin
Published in Infection and Immunity (01-05-2011)“…Chitin is a skeletal cell wall polysaccharide of the inner cell wall of fungal pathogens. As yet, little about its role during fungus-host immune cell…”
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Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata
Published in Infection and Immunity (01-03-2014)“…OA Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Early Stop Polymorphism in Human DECTIN-1 Is Associated with Increased Candida Colonization in Hematopoietic Stem Cell Transplant Recipients
Published in Clinical infectious diseases (01-09-2009)“…Background. Intensive treatment of hematological malignancies with hematopoietic stem cell transplantation (HSCT) is accompanied by a high incidence of…”
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A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans
Published in The Journal of infectious diseases (31-07-2019)“…Candidemia, one of the most common causes of fungal bloodstream infection, leads to mortality rates up to 40% in affected patients. Understanding genetic…”
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Dendritic Cell Interaction with Candida albicans Critically Depends on N-Linked Mannan
Published in The Journal of biological chemistry (18-07-2008)“…The fungus Candida albicans is the most common cause of mycotic infections in immunocompromised hosts. Little is known about the initial interactions between…”
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Toll-like Receptor 1 Polymorphisms Increase Susceptibility to Candidemia
Published in The Journal of infectious diseases (15-03-2012)“…Background. Candidemia is a severe invasive fungal infection with high mortality. Recognition of Candida species is mediated through pattern recognition…”
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Classical Borrelia Serology Does Not Aid in the Diagnosis of Persistent Symptoms Attributed to Lyme Borreliosis: A Retrospective Cohort Study
Published in Life (Basel, Switzerland) (06-05-2023)“…The diagnosis of Lyme borreliosis is based on two-tier testing using an ELISA and Western blot. About 5-10% of patients report persistent symptoms of unknown…”
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